Chimeric antigen receptor (CAR)+ T cell selection method affects transgene efficacy

por Rushworth, David, Mi, Tiejuan, Olivares, Simon, Carrero, Rosa Santana, Yang, Ge, Najjar, Amer, Cooper, Laurence
Publicado 2013

Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering

por Zong, Shan, Mi, Tiejuan, Flores, Leo G., Alpert, Amir, Olivares, Simon, Patel, Krina, Maiti, Sourindra, Mcnamara, George, Cooper, Laurence J. N., Torikai, Hiroki
Publicado 2020

Bioengineering cytotoxic T cells to target opportunistic fungal infection

por Kumaresan, Pappanaicken, Manuri, Pallavi R, Albert, Nathaniel, Rabinovich, Brian, Olivares, Simon, Maiti, Sourindra N, Huls, Helen, Lee, Dean A, Kontoyiannis, Dimitrios, Cooper, Laurence J
Publicado 2013

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood

por Huls, M. Helen, Figliola, Matthew J., Dawson, Margaret J., Olivares, Simon, Kebriaei, Partow, Shpall, Elizabeth J., Champlin, Richard E., Singh, Harjeet, Cooper, Laurence J.N.
Publicado 2013

Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of V(L) and V(H) Domains Targeting CD123(+) Tumors

por Thokala, Radhika, Olivares, Simon, Mi, Tiejuan, Maiti, Sourindra, Deniger, Drew, Huls, Helen, Torikai, Hiroki, Singh, Harjeet, Champlin, Richard E., Laskowski, Tamara, McNamara, George, Cooper, Laurence J. N.
Publicado 2016

Manufacture of Clinical-Grade CD19-Specific T Cells Stably Expressing Chimeric Antigen Receptor Using Sleeping Beauty System and Artificial Antigen Presenting Cells

por Singh, Harjeet, Figliola, Matthew J., Dawson, Margaret J., Olivares, Simon, Zhang, Ling, Yang, Ge, Maiti, Sourindra, Manuri, Pallavi, Senyukov, Vladimir, Jena, Bipulendu, Kebriaei, Partow, Champlin, Richard E., Huls, Helen, Cooper, Laurence J. N.
Publicado 2013

Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations

por Deniger, Drew C., Yu, Jianqiang, Huls, M. Helen, Figliola, Matthew J., Mi, Tiejuan, Maiti, Sourindra N., Widhopf, George F., Hurton, Lenka V., Thokala, Radhika, Singh, Harjeet, Olivares, Simon, Champlin, Richard E., Wierda, William G., Kipps, Thomas J., Cooper, Laurence J. N.
Publicado 2015

Sleeping beauty generated CD19 CAR T-Cell therapy for advanced B-Cell hematological malignancies

por Singh, Harjeet, Srour, Samer A., Milton, Denái R., McCarty, Jessica, Dai, Cuiping, Gaballa, Mahmoud R., Ammari, Mariam, Olivares, Simon, Huls, Helen, De Groot, Eleanor, Marin, David, Petropoulos, Demetrios, Olson, Amanda L., Anderlini, Paolo, Im, Jin S., Khouri, Issa, Hosing, Chitra M., Rezvani, Katayoun, Champlin, Richard E., Shpall, Elizabeth J., Cooper, Laurence J. N., Kebriaei, Partow
Publicado 2022