Evaluation of the Success of High-Throughput Physiologically Based Pharmacokinetic (HT-PBPK) Modeling Predictions to Inform Early Drug Discovery

por Naga, Doha, Parrott, Neil, Ecker, Gerhard F., Olivares-Morales, Andrés
Publicado 2022

A “middle‐out approach” for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models

por Yau, Estelle, Gertz, Michael, Ogungbenro, Kayode, Aarons, Leon, Olivares‐Morales, Andrés
Publicado 2023

Investigation of simplified physiologically‐based pharmacokinetic models in rat and human

por Yau, Estelle, Olivares‐Morales, Andrés, Ogungbenro, Kayode, Aarons, Leon, Gertz, Michael
Publicado 2023

Animal versus human oral drug bioavailability: Do they correlate?

por Musther, Helen, Olivares-Morales, Andrés, Hatley, Oliver J.D., Liu, Bo, Rostami Hodjegan, Amin
Publicado 2014

The Use of ROC Analysis for the Qualitative Prediction of Human Oral Bioavailability from Animal Data

por Olivares-Morales, Andrés, Hatley, Oliver J. D., Turner, David, Galetin, Aleksandra, Aarons, Leon, Rostami-Hodjegan, Amin
Publicado 2013

Pediatric Pharmacokinetics and Dose Predictions: A Report of a Satellite Meeting to the 10th Juvenile Toxicity Symposium

por van Groen, Bianca D., Pilla Reddy, Venkatesh, Badée, Justine, Olivares‐Morales, Andrés, Johnson, Trevor N., Nicolaï, Johan, Annaert, Pieter, Smits, Anne, de Wildt, Saskia N., Knibbe, Catherijne A. J., de Zwart, Loeckie
Publicado 2020

Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective

por Riedmaier, Arian Emami, DeMent, Kevin, Huckle, James, Bransford, Phil, Stillhart, Cordula, Lloyd, Richard, Alluri, Ravindra, Basu, Sumit, Chen, Yuan, Dhamankar, Varsha, Dodd, Stephanie, Kulkarni, Priyanka, Olivares-Morales, Andrés, Peng, Chi-Chi, Pepin, Xavier, Ren, Xiaojun, Tran, Thuy, Tistaert, Christophe, Heimbach, Tycho, Kesisoglou, Filippos, Wagner, Christian, Parrott, Neil
Publicado 2020