Generation and ex vivo culture of murine and human pancreatic ductal adenocarcinoma tissue slice explants

por Decker-Farrell, Amanda R., Ma, Alice, Li, Fangda, Muir, Alexander, Olive, Kenneth P.
Publicado 2023

Generation of orthotopic patient-derived xenograft models for pancreatic cancer using tumor slices

por Curiel-Garcia, Alvaro, Decker-Farrell, Amanda R., Sastra, Stephen A., Olive, Kenneth P.
Publicado 2022

Alternative polyadenylation drives oncogenic gene expression in pancreatic ductal adenocarcinoma

por Venkat, Swati, Tisdale, Arwen A., Schwarz, Johann R., Alahmari, Abdulrahman A., Maurer, H. Carlo, Olive, Kenneth P., Eng, Kevin H., Feigin, Michael E.
Publicado 2020

Differential Expression of Polyamine Pathways in Human Pancreatic Tumor Progression and Effects of Polyamine Blockade on Tumor Microenvironment

por Nakkina, Sai Preethi, Gitto, Sarah B., Pandey, Veethika, Parikh, Jignesh G., Geerts, Dirk, Maurer, Hans Carlo, Olive, Kenneth P., Phanstiel, Otto, Altomare, Deborah A.
Publicado 2021

Enteroendocrine Cell Formation Is an Early Event in Pancreatic Tumorigenesis

por Caplan, Leah R., Vavinskaya, Vera, Gelikman, David G., Jyotsana, Nidhi, Trinh, Vincent Q., Olive, Kenneth P., Tan, Marcus C. B., DelGiorno, Kathleen E.
Publicado 2022

Pervasiveness of HLA allele-specific expression loss across tumor types

por Filip, Ioan, Wang, Anqi, Kravets, Oleksandr, Orenbuch, Rose, Zhao, Junfei, Perea-Chamblee, Tomin E., Manji, Gulam A., López de Maturana, Evangelina, Malats, Núria, Olive, Kenneth P., Rabadan, Raul
Publicado 2023

A novel method for quantification of gemcitabine and its metabolites 2′,2′-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC–MS/MS: comparison with (19)F NMR...

por Bapiro, Tashinga E., Richards, Frances M., Goldgraben, Mae A., Olive, Kenneth P., Madhu, Basetti, Frese, Kristopher K., Cook, Natalie, Jacobetz, Michael A., Smith, Donna-Michelle, Tuveson, David A., Griffiths, John R., Jodrell, Duncan I.
Publicado 2011

Proteomic analysis of gemcitabine-resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment

por Le Large, Tessa Ya Sung, El Hassouni, Btissame, Funel, Niccola, Kok, Bart, Piersma, Sander R., Pham, Thang V., Olive, Kenneth P., Kazemier, Geert, van Laarhoven, Hanneke W.M., Jimenez, Connie R., Bijlsma, Maarten F., Giovannetti, Elisa
Publicado 2019

Amyloid Precursor-like Protein 2 Expression Increases during Pancreatic Cancer Development and Shortens the Survival of a Spontaneous Mouse Model of Pancreatic Cancer

por Poelaert, Brittany J., Knoche, Shelby M., Larson, Alaina C., Pandey, Poomy, Seshacharyulu, Parthasarathy, Khan, Nuzhat, Maurer, H. Carlo, Olive, Kenneth P., Sheinin, Yuri, Ahmad, Rizwan, Singh, Amar B., Batra, Surinder K., Rachagani, Satyanarayana, Solheim, Joyce C.
Publicado 2021

Noninvasive Young's modulus visualization of fibrosis progression and delineation of pancreatic ductal adenocarcinoma (PDAC) tumors using Harmonic Motion Elastography (HME) in vivo

por Nabavizadeh, Alireza, Payen, Thomas, Iuga, Alina C., Sagalovskiy, Irina R., Desrouilleres, Deborah, Saharkhiz, Niloufar, Palermo, Carmine F., Sastra, Stephen A., Oberstein, Paul E., Rosario, Vilma, Kluger, Michael D., Schrope, Beth A., Chabot, John A., Olive, Kenneth P., Konofagou, Elisa E.
Publicado 2020

The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer

por Michaelis, Katherine A., Norgard, Mason A., Zhu, Xinxia, Levasseur, Peter R., Sivagnanam, Shamilene, Liudahl, Shannon M., Burfeind, Kevin G., Olson, Brennan, Pelz, Katherine R., Angeles Ramos, Diana M., Maurer, H. Carlo, Olive, Kenneth P., Coussens, Lisa M., Morgan, Terry K., Marks, Daniel L.
Publicado 2019

Publisher Correction: The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer

por Michaelis, Katherine A., Norgard, Mason A., Zhu, Xinxia, Levasseur, Peter R., Sivagnanam, Shamilene, Liudahl, Shannon M., Burfeind, Kevin G., Olson, Brennan, Pelz, Katherine R., Ramos, Diana M. Angeles, Maurer, H. Carlo, Olive, Kenneth P., Coussens, Lisa M., Morgan, Terry K., Marks, Daniel L.
Publicado 2019

PALLD mutation in a European family conveys a stromal predisposition for familial pancreatic cancer

por Liotta, Lucia, Lange, Sebastian, Maurer, H. Carlo, Olive, Kenneth P., Braren, Rickmer, Pfarr, Nicole, Burger, Sebastian, Muckenhuber, Alexander, Jesinghaus, Moritz, Steiger, Katja, Weichert, Wilko, Friess, Helmut, Schmid, Roland, Algül, Hana, Jost, Philipp J., Ramser, Juliane, Fischer, Christine, Quante, Anne S., Reichert, Maximilian, Quante, Michael
Publicado 2021

Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer

por Scales, Michael K., Velez-Delgado, Ashley, Steele, Nina G., Schrader, Hannah E., Stabnick, Anna M., Yan, Wei, Mercado Soto, Nayanna M., Nwosu, Zeribe C., Johnson, Craig, Zhang, Yaqing, Salas-Escabillas, Daniel J., Menjivar, Rosa E., Maurer, H. Carlo, Crawford, Howard C., Bednar, Filip, Olive, Kenneth P., Pasca di Magliano, Marina, Allen, Benjamin L.
Publicado 2022

Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer

por Maurer, H. Carlo, Curiel-Garcia, Alvaro, Holmstrom, Sam, Laise, Pasquale, Palermo, Carmine F., Sastra, Steven A., Andren, Anthony, Li, Zhang, LeLarge, Tessa, Sagalovskiy, Irina, Ross, Daniel R., Rosario, Vilma, Lu, Kate, Ferraiuolo, Ethan, Spinosa, Nicholas, Wong, Winston, Shaw, Kaitlin, Chabot, John A., Genkinger, Jeanine, Hibshoosh, Hanina, Manji, Gulam A., Iuga, Alina, Schmid, Roland M., Badgley, Michael A., Johnson, Kristen, Califano, Andrea, Lyssiotis, Costas, Olive, Kenneth P.
Publicado 2023

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

por Kremer, Daniel M., Nelson, Barbara S., Lin, Lin, Yarosz, Emily L., Halbrook, Christopher J., Kerk, Samuel A., Sajjakulnukit, Peter, Myers, Amy, Thurston, Galloway, Hou, Sean W., Carpenter, Eileen S., Andren, Anthony C., Nwosu, Zeribe C., Cusmano, Nicholas, Wisner, Stephanie, Mbah, Nneka E., Shan, Mengrou, Das, Nupur K., Magnuson, Brian, Little, Andrew C., Savani, Milan R., Ramos, Johanna, Gao, Tina, Sastra, Stephen A., Palermo, Carmine F., Badgley, Michael A., Zhang, Li, Asara, John M., McBrayer, Samuel K., di Magliano, Marina Pasca, Crawford, Howard C., Shah, Yatrik M., Olive, Kenneth P., Lyssiotis, Costas A.
Publicado 2021