Characterisation of putative class 1A DHODH-like proteins from Mucorales and dematiaceous mould species

por Pinder, Corinne, Lebedinec, Ressa, Levine, Tim P., Birch, Mike, Oliver, Jason D.
Publicado 2023

Characterisation of the Candida albicans Phosphopantetheinyl Transferase Ppt2 as a Potential Antifungal Drug Target

por Dobb, Katharine S., Kaye, Sarah J., Beckmann, Nicola, Thain, John L., Stateva, Lubomira, Birch, Mike, Oliver, Jason D.
Publicado 2015

Madurella mycetomatis, the main causative agent of eumycetoma, is highly susceptible to olorofim

por Lim, Wilson, Eadie, Kimberly, Konings, Mickey, Rijnders, Bart, Fahal, Ahmed H, Oliver, Jason D, Birch, Mike, Verbon, Annelies, van de Sande, Wendy
Publicado 2020

The Dynamic Influence of Olorofim (F901318) on the Cell Morphology and Organization of Living Cells of Aspergillus fumigatus

por du Pré, Saskia, Birch, Mike, Law, Derek, Beckmann, Nicola, Sibley, Graham E. M., Bromley, Michael J., Read, Nick D., Oliver, Jason D.
Publicado 2020

The Aspergillus fumigatus Dihydroxyacid Dehydratase Ilv3A/IlvC Is Required for Full Virulence

por Oliver, Jason D., Kaye, Sarah J., Tuckwell, Danny, Johns, Anna E., Macdonald, Darel A., Livermore, Joanne, Warn, Peter A., Birch, Mike, Bromley, Michael J.
Publicado 2012

Resistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistance

por Buil, Jochem B., Oliver, Jason D., Law, Derek, Baltussen, Tim, Zoll, Jan, Hokken, Margriet W. J., Tehupeiory-Kooreman, Marlou, Melchers, Willem J. G., Birch, Mike, Verweij, Paul E.
Publicado 2022

A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus...

por Johns, Anna, Scharf, Daniel H., Gsaller, Fabio, Schmidt, Hella, Heinekamp, Thorsten, Straßburger, Maria, Oliver, Jason D., Birch, Mike, Beckmann, Nicola, Dobb, Katharine S., Gilsenan, Jane, Rash, Bharatkumar, Bignell, Elaine, Brakhage, Axel A., Bromley, Michael J.
Publicado 2017

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance

por Hope, William, Stone, Neil R. H., Johnson, Adam, McEntee, Laura, Farrington, Nicola, Santoro-Castelazo, Anahi, Liu, Xuan, Lucaci, Anita, Hughes, Margaret, Oliver, Jason D., Giamberardino, Charles, Mfinanga, Sayoki, Harrison, Thomas S., Perfect, John R., Bicanic, Tihana
Publicado 2019