Mighty mouse breakthroughs: a Sox2-driven model for squamous cell lung cancer

por Mukhopadhyay, Anandaroop, Oliver, Trudy G
Publicado 2014

Killing SCLC: insights into how to target a shapeshifting tumor

por Sutherland, Kate D., Ireland, Abbie S., Oliver, Trudy G.
Publicado 2022

A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest

por Tsabar, Michael, Mock, Caroline S., Venkatachalam, Veena, Reyes, Jose, Karhohs, Kyle W., Oliver, Trudy G., Regev, Aviv, Jambhekar, Ashwini, Lahav, Galit
Publicado 2020

Sox2 Cooperates with Lkb1 Loss in a Mouse Model of Squamous Cell Lung Cancer

por Mukhopadhyay, Anandaroop, Berrett, Kristofer C., Kc, Ushma, Clair, Phillip M., Pop, Stelian M., Carr, Shamus R., Witt, Benjamin L., Oliver, Trudy G.
Publicado 2014

GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer

por Masin, Mark, Vazquez, Jessica, Rossi, Simona, Groeneveld, Svenja, Samson, Natasha, Schwalie, Petra C, Deplancke, Bart, Frawley, Laura E, Gouttenoire, Jérôme, Moradpour, Darius, Oliver, Trudy G, Meylan, Etienne
Publicado 2014

Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells

por Melnikova, Margarita, Wauer, Ulrike Sophie, Mendus, Diana, Hilger, Ralf Axel, Oliver, Trudy G., Mercer, Kim, Gohlke, Björn Oliver, Erdmann, Kati, Niederacher, Dieter, Neubauer, Hans, Buderath, Paul, Wimberger, Pauline, Kuhlmann, Jan Dominik, Thomale, Jürgen
Publicado 2020

ASCL1 represses a SOX9(+) neural crest stem-like state in small cell lung cancer

por Olsen, Rachelle R., Ireland, Abbie S., Kastner, David W., Groves, Sarah M., Spainhower, Kyle B., Pozo, Karine, Kelenis, Demetra P., Whitney, Christopher P., Guthrie, Matthew R., Wait, Sarah J., Soltero, Danny, Witt, Benjamin L., Quaranta, Vito, Johnson, Jane E., Oliver, Trudy G.
Publicado 2021

Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer

por Cargill, Kasey R., Stewart, C. Allison, Park, Elizabeth M., Ramkumar, Kavya, Gay, Carl M., Cardnell, Robert J., Wang, Qi, Diao, Lixia, Shen, Li, Fan, You-Hong, Chan, Wai Kin, Lorenzi, Philip L., Oliver, Trudy G., Wang, Jing, Byers, Lauren A.
Publicado 2021

Protein expression of TTF1 and cMYC define distinct molecular subgroups of small cell lung cancer with unique vulnerabilities to aurora kinase inhibition, DLL3 targeting, and other...

por Cardnell, Robert J., Li, Lerong, Sen, Triparna, Bara, Rasha, Tong, Pan, Fujimoto, Junya, Ireland, Abbie S., Guthrie, Matthew R., Bheddah, Sheila, Banerjee, Upasana, Kalu, Nene N., Fan, You-Hong, Dylla, Scott J., Johnson, Faye M., Wistuba, Ignacio I., Oliver, Trudy G., Heymach, John V., Glisson, Bonnie S., Wang, Jing, Byers, Lauren A.
Publicado 2017

Lineage Plasticity in SCLC Generates Non-Neuroendocrine Cells Primed for Vasculogenic Mimicry

por Pearsall, Sarah M., Williamson, Stuart C., Humphrey, Sam, Hughes, Ellyn, Morgan, Derrick, Marqués, Fernando J. García, Awanis, Griselda, Carroll, Rebecca, Burks, Laura, Shue, Yan Ting, Bermudez, Abel, Frese, Kristopher K., Galvin, Melanie, Carter, Mathew, Priest, Lynsey, Kerr, Alastair, Zhou, Cong, Oliver, Trudy G., Humphries, Jonathan D., Humphries, Martin J., Blackhall, Fiona, Cannell, Ian G., Pitteri, Sharon J., Hannon, Gregory J., Sage, Julien, Dive, Caroline, Simpson, Kathryn L.
Publicado 2023

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer

por Dammert, Marcel A., Brägelmann, Johannes, Olsen, Rachelle R., Böhm, Stefanie, Monhasery, Niloufar, Whitney, Christopher P., Chalishazar, Milind D., Tumbrink, Hannah L., Guthrie, Matthew R., Klein, Sebastian, Ireland, Abbie S., Ryan, Jeremy, Schmitt, Anna, Marx, Annika, Ozretić, Luka, Castiglione, Roberta, Lorenz, Carina, Jachimowicz, Ron D., Wolf, Elmar, Thomas, Roman K., Poirier, John T., Büttner, Reinhard, Sen, Triparna, Byers, Lauren A., Reinhardt, H. Christian, Letai, Anthony, Oliver, Trudy G., Sos, Martin L.
Publicado 2019

Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer

por Wagner, Alex H., Devarakonda, Siddhartha, Skidmore, Zachary L., Krysiak, Kilannin, Ramu, Avinash, Trani, Lee, Kunisaki, Jason, Masood, Ashiq, Waqar, Saiama N., Spies, Nicholas C., Morgensztern, Daniel, Waligorski, Jason, Ponce, Jennifer, Fulton, Robert S., Maggi, Leonard B., Weber, Jason D., Watson, Mark A., O’Conor, Christopher J., Ritter, Jon H., Olsen, Rachelle R., Cheng, Haixia, Mukhopadhyay, Anandaroop, Can, Ismail, Cessna, Melissa H., Oliver, Trudy G., Mardis, Elaine R., Wilson, Richard K., Griffith, Malachi, Griffith, Obi L., Govindan, Ramaswamy
Publicado 2018