Restoration of fitness lost due to dysregulation of the pyruvate dehydrogenase complex is triggered by ribosomal binding site modifications

por Anand, Amitesh, Olson, Connor A., Sastry, Anand V., Patel, Arjun, Szubin, Richard, Yang, Laurence, Feist, Adam M., Palsson, Bernhard O.
Publicado 2021

Laboratory evolution of synthetic electron transport system variants reveals a larger metabolic respiratory system and its plasticity

por Anand, Amitesh, Patel, Arjun, Chen, Ke, Olson, Connor A., Phaneuf, Patrick V., Lamoureux, Cameron, Hefner, Ying, Szubin, Richard, Feist, Adam M., Palsson, Bernhard O.
Publicado 2022

Reframing gene essentiality in terms of adaptive flexibility

por Guzmán, Gabriela I., Olson, Connor A., Hefner, Ying, Phaneuf, Patrick V., Catoiu, Edward, Crepaldi, Lais B., Micas, Lucas Goldschmidt, Palsson, Bernhard O., Feist, Adam M.
Publicado 2018

Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus

por Machado, Henrique, Seif, Yara, Sakoulas, George, Olson, Connor A., Hefner, Ying, Anand, Amitesh, Jones, Ying Z., Szubin, Richard, Palsson, Bernhard O., Nizet, Victor, Feist, Adam M.
Publicado 2021

Revealing 29 sets of independently modulated genes in Staphylococcus aureus, their regulators, and role in key physiological response

por Poudel, Saugat, Tsunemoto, Hannah, Seif, Yara, Sastry, Anand V., Szubin, Richard, Xu, Sibei, Machado, Henrique, Olson, Connor A., Anand, Amitesh, Pogliano, Joe, Nizet, Victor, Palsson, Bernhard O.
Publicado 2020

OxyR Is a Convergent Target for Mutations Acquired during Adaptation to Oxidative Stress-Prone Metabolic States

por Anand, Amitesh, Chen, Ke, Catoiu, Edward, Sastry, Anand V, Olson, Connor A, Sandberg, Troy E, Seif, Yara, Xu, Sibei, Szubin, Richard, Yang, Laurence, Feist, Adam M, Palsson, Bernhard O
Publicado 2020

Adaptive evolution reveals a tradeoff between growth rate and oxidative stress during naphthoquinone-based aerobic respiration

por Anand, Amitesh, Chen, Ke, Yang, Laurence, Sastry, Anand V., Olson, Connor A., Poudel, Saugat, Seif, Yara, Hefner, Ying, Phaneuf, Patrick V., Xu, Sibei, Szubin, Richard, Feist, Adam M., Palsson, Bernhard O.
Publicado 2019

The genetic basis for adaptation of model-designed syntrophic co-cultures

por Lloyd, Colton J., King, Zachary A., Sandberg, Troy E., Hefner, Ying, Olson, Connor A., Phaneuf, Patrick V., O’Brien, Edward J., Sanders, Jon G., Salido, Rodolfo A., Sanders, Karenina, Brennan, Caitriona, Humphrey, Gregory, Knight, Rob, Feist, Adam M.
Publicado 2019

Characterization of CA-MRSA TCH1516 exposed to nafcillin in bacteriological and physiological media

por Poudel, Saugat, Tsunemoto, Hannah, Meehan, Michael, Szubin, Richard, Olson, Connor A., Lamsa, Anne, Seif, Yara, Dillon, Nicholas, Vrbanac, Alison, Sugie, Joseph, Dahesh, Samira, Monk, Jonathan M., Dorrestein, Pieter C., Pogliano, Joseph, Knight, Rob, Nizet, Victor, Palsson, Bernhard O., Feist, Adam M.
Publicado 2019

Profiling the effect of nafcillin on HA-MRSA D712 using bacteriological and physiological media

por Rajput, Akanksha, Poudel, Saugat, Tsunemoto, Hannah, Meehan, Michael, Szubin, Richard, Olson, Connor A., Lamsa, Anne, Seif, Yara, Dillon, Nicholas, Vrbanac, Alison, Sugie, Joseph, Dahesh, Samira, Monk, Jonathan M., Dorrestein, Pieter C., Knight, Rob, Nizet, Victor, Palsson, Bernhard O., Feist, Adam M., Pogliano, Joe
Publicado 2019

Identifying the effect of vancomycin on health care–associated methicillin-resistant Staphylococcus aureus strains using bacteriological and physiological media

por Rajput, Akanksha, Poudel, Saugat, Tsunemoto, Hannah, Meehan, Michael, Szubin, Richard, Olson, Connor A, Seif, Yara, Lamsa, Anne, Dillon, Nicholas, Vrbanac, Alison, Sugie, Joseph, Dahesh, Samira, Monk, Jonathan M, Dorrestein, Pieter C, Knight, Rob, Pogliano, Joe, Nizet, Victor, Feist, Adam M, Palsson, Bernhard O
Publicado 2021