Comparative analysis of dCas9-VP64 variants and multiplexed guide RNAs mediating CRISPR activation

por Omachi, Kohei, Miner, Jeffrey H.
Publicado 2022

NanoLuc reporters identify COL4A5 nonsense mutations susceptible to drug-induced stop codon readthrough

por Omachi, Kohei, Kai, Hirofumi, Roberge, Michel, Miner, Jeffrey H.
Publicado 2022

A single-cell multiomic analysis of kidney organoid differentiation

por Yoshimura, Yasuhiro, Muto, Yoshiharu, Ledru, Nicolas, Wu, Haojia, Omachi, Kohei, Miner, Jeffrey H., Humphreys, Benjamin D.
Publicado 2023

Bromide supplementation exacerbated the renal dysfunction, injury and fibrosis in a mouse model of Alport syndrome

por Yokota, Tsubasa, Omachi, Kohei, Suico, Mary Ann, Kojima, Haruka, Kamura, Misato, Teramoto, Keisuke, Kaseda, Shota, Kuwazuru, Jun, Shuto, Tsuyoshi, Kai, Hirofumi
Publicado 2017

Trimerization and Genotype–Phenotype Correlation of COL4A5 Mutants in Alport Syndrome

por Kamura, Misato, Yamamura, Tomohiko, Omachi, Kohei, Suico, Mary Ann, Nozu, Kandai, Kaseda, Shota, Kuwazuru, Jun, Shuto, Tsuyoshi, Iijima, Kazumoto, Kai, Hirofumi
Publicado 2020

Mild electrical stimulation with heat shock attenuates renal pathology in adriamycin-induced nephrotic syndrome mouse model

por Teramoto, Keisuke, Tsurekawa, Yu, Suico, Mary Ann, Kaseda, Shota, Omachi, Kohei, Yokota, Tsubasa, Kamura, Misato, Piruzyan, Mariam, Kondo, Tatsuya, Shuto, Tsuyoshi, Araki, Eiichi, Kai, Hirofumi
Publicado 2020

Combined effects of cisplatin and photon or proton irradiation in cultured cells: radiosensitization, patterns of cell death and cell cycle distribution

por Iwata, Hiromitsu, Shuto, Tsuyoshi, Kamei, Shunsuke, Omachi, Kohei, Moriuchi, Masataka, Omachi, Chihiro, Toshito, Toshiyuki, Hashimoto, Shingo, Nakajima, Koichiro, Sugie, Chikao, Ogino, Hiroyuki, Kai, Hirofumi, Shibamoto, Yuta
Publicado 2020

Creation of Philadelphia chromosome by CRISPR/Cas9-mediated double cleavages on BCR and ABL1 genes as a model for initial event in leukemogenesis

por Tamai, Minori, Fujisawa, Shinichi, Nguyen, Thao T. T., Komatsu, Chiaki, Kagami, Keiko, Kamimoto, Kenji, Omachi, Kohei, Kasai, Shin, Harama, Daisuke, Watanabe, Atsushi, Akahane, Koshi, Goi, Kumiko, Naka, Kazuhito, Kaname, Tadashi, Teshima, Takanori, Inukai, Takeshi
Publicado 2022

Metformin ameliorates the severity of experimental Alport syndrome

por Omachi, Kohei, Kaseda, Shota, Yokota, Tsubasa, Kamura, Misato, Teramoto, Keisuke, Kuwazuru, Jun, Kojima, Haruka, Nohara, Hirofumi, Koyama, Kosuke, Ohtsuki, Sumio, Misumi, Shogo, Takeo, Toru, Nakagata, Naomi, Li, Jian-Dong, Shuto, Tsuyoshi, Suico, Mary Ann, Miner, Jeffrey H., Kai, Hirofumi
Publicado 2021

CyclosporinA Derivative as Therapeutic Candidate for Alport Syndrome by Inducing Mutant Type IV Collagen Secretion

por Kuwazuru, Jun, Suico, Mary Ann, Omachi, Kohei, Kojima, Haruka, Kamura, Misato, Kaseda, Shota, Kawahara, Teppei, Hitora, Yuki, Kato, Hikaru, Tsukamoto, Sachiko, Wada, Mikiyo, Asano, Toshifumi, Kotani, Shunsuke, Nakajima, Makoto, Misumi, Shogo, Sannomiya, Yuya, Horizono, Jun, Koyama, Yuimi, Owaki, Aimi, Shuto, Tsuyoshi, Kai, Hirofumi
Publicado 2023

Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis

por Muto, Yoshiharu, Dixon, Eryn E., Yoshimura, Yasuhiro, Wu, Haojia, Omachi, Kohei, Ledru, Nicolas, Wilson, Parker C., King, Andrew J., Eric Olson, N., Gunawan, Marvin G., Kuo, Jay J., Cox, Jennifer H., Miner, Jeffrey H., Seliger, Stephen L., Woodward, Owen M., Welling, Paul A., Watnick, Terry J., Humphreys, Benjamin D.
Publicado 2022

Development of an exon skipping therapy for X-linked Alport syndrome with truncating variants in COL4A5

por Yamamura, Tomohiko, Horinouchi, Tomoko, Adachi, Tomomi, Terakawa, Maki, Takaoka, Yutaka, Omachi, Kohei, Takasato, Minoru, Takaishi, Kiyosumi, Shoji, Takao, Onishi, Yoshiyuki, Kanazawa, Yoshito, Koizumi, Makoto, Tomono, Yasuko, Sugano, Aki, Shono, Akemi, Minamikawa, Shogo, Nagano, China, Sakakibara, Nana, Ishiko, Shinya, Aoto, Yuya, Kamura, Misato, Harita, Yutaka, Miura, Kenichiro, Kanda, Shoichiro, Morisada, Naoya, Rossanti, Rini, Ye, Ming Juan, Nozu, Yoshimi, Matsuo, Masafumi, Kai, Hirofumi, Iijima, Kazumoto, Nozu, Kandai
Publicado 2020