The genetics of breast cancer risk in the post-genome era: thoughts on study design to move past BRCA and towards clinical relevance

por Skol, Andrew D., Sasaki, Mark M., Onel, Kenan
Publicado 2016

The Functional Hallmarks of Cancer Predisposition Genes

por Capellini, Alexandra, Williams, Matthew, Onel, Kenan, Huang, Kuan-Lin
Publicado 2021

Precision oncology: lessons learned and challenges for the future

por Yang, Hsih-Te, Shah, Ronak H, Tegay, David, Onel, Kenan
Publicado 2019

Integrative genetic analysis suggests that skin color modifies the genetic architecture of melanoma

por Hulur, Imge, Skol, Andrew D., Gamazon, Eric R., Cox, Nancy J., Onel, Kenan
Publicado 2017

Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristics

por Esai Selvan, Myvizhi, Onel, Kenan, Gnjatic, Sacha, Klein, Robert J., Gümüş, Zeynep H.
Publicado 2023

ExScalibur: A High-Performance Cloud-Enabled Suite for Whole Exome Germline and Somatic Mutation Identification

por Bao, Riyue, Hernandez, Kyle, Huang, Lei, Kang, Wenjun, Bartom, Elizabeth, Onel, Kenan, Volchenboum, Samuel, Andrade, Jorge
Publicado 2015

Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci

por Hulur, Imge, Gamazon, Eric R, Skol, Andrew D, Xicola, Rosa M, Llor, Xavier, Onel, Kenan, Ellis, Nathan A, Kupfer, Sonia S
Publicado 2015

Identification and Utilization of Donor and Recipient Genetic Variants to Predict Survival After HCT: Are We Ready for Primetime?

por Sucheston-Campbell, Lara E., Clay, Alyssa, McCarthy, Philip L., Zhu, Qianqian, Preus, Leah, Pasquini, Marcelo, Onel, Kenan, Hahn, Theresa
Publicado 2015

Prediction of breast cancer risk based on flow variant analysis of circulating peripheral blood mononuclear cells

por Loke, Johnny, Alim, Ishraq, Yam, Sarah, Klugman, Susan, Xia, Li C., Gruber, Dorota, Tegay, David, LaBella, Andrea, Onel, Kenan, Ostrer, Harry
Publicado 2022

Systematic computation with functional gene-sets among leukemic and hematopoietic stem cells reveals a favorable prognostic signature for acute myeloid leukemia

por Yang, Xinan Holly, Li, Meiyi, Wang, Bin, Zhu, Wanqi, Desgardin, Aurelie, Onel, Kenan, de Jong, Jill, Chen, Jianjun, Chen, Luonan, Cunningham, John M
Publicado 2015

Next generation sequencing reveals clinically actionable molecular markers in myeloid sarcoma

por Li, Zejuan, Stölzel, Friedrich, Onel, Kenan, Sukhanova, Madina, Mirza, M. Kamran, Yap, Kai Lee, Borinets, Olesya, Larson, Richard A., Stock, Wendy, Sasaki, Mark M., Joseph, Loren, Raca, Gordana
Publicado 2015

A p53-regulated apoptotic gene signature predicts treatment response and outcome in pediatric acute lymphoblastic leukemia

por Bainer, Russell O, Trendowski, Matthew R, Cheng, Cheng, Pei, Deqing, Yang, Wenjian, Paugh, Steven W, Goss, Kathleen H, Skol, Andrew D, Pavlidis, Paul, Pui, Ching-Hon, Gilliam, T Conrad, Evans, William E, Onel, Kenan
Publicado 2017

Patient similarity network of newly diagnosed multiple myeloma identifies patient subgroups with distinct genetic features and clinical implications

por Bhalla, Sherry, Melnekoff, David T., Aleman, Adolfo, Leshchenko, Violetta, Restrepo, Paula, Keats, Jonathan, Onel, Kenan, Sawyer, Jeffrey R., Madduri, Deepu, Richter, Joshua, Richard, Shambavi, Chari, Ajai, Cho, Hearn Jay, Dudley, Joel T., Jagannath, Sundar, Laganà, Alessandro, Parekh, Samir
Publicado 2021

Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor

por Voce, David J., Schmitt, Adam M., Uppal, Abhineet, McNerney, Megan E., Bernal, Giovanna M., Cahill, Kirk E., Wahlstrom, Joshua S., Nassiri, Ashley, Yu, Xiaohong, Crawley, Clayton D., White, Kevin P., Onel, Kenan, Weichselbaum, Ralph R., Yamini, Bakhtiar
Publicado 2014

CBL Is Frequently Altered in Lung Cancers: Its Relationship to Mutations in MET and EGFR Tyrosine Kinases

por Tan, Yi-Hung Carol, Krishnaswamy, Soundararajan, Nandi, Suvobroto, Kanteti, Rajani, Vora, Sapana, Onel, Kenan, Hasina, Rifat, Lo, Fang-Yi, El-Hashani, Essam, Cervantes, Gustavo, Robinson, Matthew, Kales, Stephen C., Lipkowitz, Stanley, Karrison, Theodore, Sattler, Martin, Vokes, Everett E., Wang, Yi-Ching, Salgia, Ravi
Publicado 2010

Ethnic Variation of TET2 SNP rs2454206 and Association with Clinical Outcome in Childhood AML: A Report from the Children’s Oncology Group

por Kutny, Matthew A., Alonzo, Todd A., Gamazon, Eric R., Gerbing, Robert B., Geraghty, Daniel, Lange, Beverly, Heerema, Nyla A., Sung, Lillian, Aplenc, Richard, Franklin, Janet, Raimondi, Susana C., Hirsch, Betsy A., Konkashbaev, Anuar, Cox, Nancy J., Onel, Kenan, Gamis, Alan S., Meshinchi, Soheil
Publicado 2015

Genetically Raised Circulating Bilirubin Levels and Risk of Ten Cancers: A Mendelian Randomization Study

por Seyed Khoei, Nazlisadat, Carreras-Torres, Robert, Murphy, Neil, Gunter, Marc J., Brennan, Paul, Smith-Byrne, Karl, Mariosa, Daniela, Mckay, James, O’Mara, Tracy A., Jarrett, Ruth, Hjalgrim, Henrik, Smedby, Karin E., Cozen, Wendy, Onel, Kenan, Diepstra, Arjan, Wagner, Karl-Heinz, Freisling, Heinz
Publicado 2021

Correction: CBL Is Frequently Altered in Lung Cancers: Its Relationship to Mutations in MET and EGFR Tyrosine Kinases

por Tan, Yi-Hung Carol, Krishnaswamy, Soundararajan, Nandi, Suvobroto, Kanteti, Rajani, Vora, Sapana, Onel, Kenan, Hasina, Rifat, Lo, Fang-Yi, El-Hashani, Essam, Cervantes, Gustavo, Robinson, Matthew, Hsu, Han-Shui, Kales, Stephen C., Lipkowitz, Stanley, Karrison, Theodore, Sattler, Martin, Vokes, Everett E., Wang, Yi-Ching, Salgia, Ravi
Publicado 2011

A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology

por Hungate, Eric A., Vora, Sapana R., Gamazon, Eric R., Moriyama, Takaya, Best, Timothy, Hulur, Imge, Lee, Younghee, Evans, Tiffany-Jane, Ellinghaus, Eva, Stanulla, Martin, Rudant, Jéremie, Orsi, Laurent, Clavel, Jacqueline, Milne, Elizabeth, Scott, Rodney J., Pui, Ching-Hon, Cox, Nancy J., Loh, Mignon L., Yang, Jun J., Skol, Andrew D., Onel, Kenan
Publicado 2016

Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)

por Gruber, Conor, Patel, Roosheel, Trachman, Rebecca, Lepow, Lauren, Amanat, Fatima, Krammer, Florian, Wilson, Karen M., Onel, Kenan, Geanon, Daniel, Tuballes, Kevin, Patel, Manishkumar, Mouskas, Konstantinos, Simons, Nicole, Barcessat, Vanessa, Valle, Diane Del, Udondem, Samantha, Kang, Gurpawan, Gangadharan, Sandeep, Ofori-Amanfo, George, Rahman, Adeeb, Kim-Schulze, Seunghee, Charney, Alexander, Gnjatic, Sacha, Gelb, Bruce D., Merad, Miriam, Bogunovic, Dusan
Publicado 2020