Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis

por Oiwa, Kotaro, Watanabe, Seiji, Onodera, Kazunari, Iguchi, Yohei, Kinoshita, Yukako, Komine, Okiru, Sobue, Akira, Okada, Yohei, Katsuno, Masahisa, Yamanaka, Koji
Publicado 2023

Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells

por Shimojo, Daisuke, Onodera, Kazunari, Doi-Torii, Yukiko, Ishihara, Yasuharu, Hattori, Chinatsu, Miwa, Yukino, Tanaka, Satoshi, Okada, Rina, Ohyama, Manabu, Shoji, Masanobu, Nakanishi, Atsushi, Doyu, Manabu, Okano, Hideyuki, Okada, Yohei
Publicado 2015

Selective suppression of polyglutamine-expanded protein by lipid nanoparticle-delivered siRNA targeting CAG expansions in the mouse CNS

por Hirunagi, Tomoki, Sahashi, Kentaro, Tachikawa, Kiyoshi, Leu, Angel I., Nguyen, Michelle, Mukthavaram, Rajesh, Karmali, Priya P., Chivukula, Padmanabh, Tohnai, Genki, Iida, Madoka, Onodera, Kazunari, Ohyama, Manabu, Okada, Yohei, Okano, Hideyuki, Katsuno, Masahisa
Publicado 2021

Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy

por Iida, Madoka, Sahashi, Kentaro, Kondo, Naohide, Nakatsuji, Hideaki, Tohnai, Genki, Tsutsumi, Yutaka, Noda, Seiya, Murakami, Ayuka, Onodera, Kazunari, Okada, Yohei, Nakatochi, Masahiro, Tsukagoshi Okabe, Yuka, Shimizu, Shinobu, Mizuno, Masaaki, Adachi, Hiroaki, Okano, Hideyuki, Sobue, Gen, Katsuno, Masahisa
Publicado 2019

Unveiling synapse pathology in spinal bulbar muscular atrophy by genome-wide transcriptome analysis of purified motor neurons derived from disease specific iPSCs

por Onodera, Kazunari, Shimojo, Daisuke, Ishihara, Yasuharu, Yano, Masato, Miya, Fuyuki, Banno, Haruhiko, Kuzumaki, Naoko, Ito, Takuji, Okada, Rina, de Araújo Herculano, Bruno, Ohyama, Manabu, Yoshida, Mari, Tsunoda, Tatsuhiko, Katsuno, Masahisa, Doyu, Manabu, Sobue, Gen, Okano, Hideyuki, Okada, Yohei
Publicado 2020

Simple and efficient differentiation of human iPSCs into contractible skeletal muscles for muscular disease modeling

por Rashid, Muhammad Irfanur, Ito, Takuji, Miya, Fuyuki, Shimojo, Daisuke, Arimoto, Kanae, Onodera, Kazunari, Okada, Rina, Nagashima, Takunori, Yamamoto, Kazuki, Khatun, Zohora, Shimul, Rayhanul Islam, Niwa, Jun-ichi, Katsuno, Masahisa, Sobue, Gen, Okano, Hideyuki, Sakurai, Hidetoshi, Shimizu, Kazunori, Doyu, Manabu, Okada, Yohei
Publicado 2023