RNA Interference Mitigates Motor and Neuropathological Deficits in a Cerebellar Mouse Model of Machado-Joseph Disease

por Nóbrega, Clévio, Nascimento-Ferreira, Isabel, Onofre, Isabel, Albuquerque, David, Déglon, Nicole, Pereira de Almeida, Luís
Publicado 2014

Silencing Mutant Ataxin-3 Rescues Motor Deficits and Neuropathology in Machado-Joseph Disease Transgenic Mice

por Nóbrega, Clévio, Nascimento-Ferreira, Isabel, Onofre, Isabel, Albuquerque, David, Hirai, Hirokazu, Déglon, Nicole, de Almeida, Luís Pereira
Publicado 2013

Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment

por Onofre, Isabel, Mendonça, Nuno, Lopes, Sara, Nobre, Rui, de Melo, Joana Barbosa, Carreira, Isabel Marques, Januário, Cristina, Gonçalves, António Freire, de Almeida, Luis Pereira
Publicado 2016

Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting

por Lopes, Carla, Tang, Yang, Anjo, Sandra I., Manadas, Bruno, Onofre, Isabel, de Almeida, Luís P., Daley, George Q., Schlaeger, Thorsten M., Rego, Ana Cristina Carvalho
Publicado 2020

Loss of hierarchical imprinting regulation at the Prader–Willi/Angelman syndrome locus in human iPSCs

por Pólvora-Brandão, Duarte, Joaquim, Mariana, Godinho, Inês, Aprile, Domenico, Álvaro, Ana Rita, Onofre, Isabel, Raposo, Ana Cláudia, Pereira de Almeida, Luís, Duarte, Sofia T, da Rocha, Simão T
Publicado 2018