Rational Design of Antirheumatic Prodrugs Specific for Sites of Inflammation

por Onuoha, Shimobi C., Ferrari, Mathieu, Sblattero, Daniele, Pitzalis, Costantino
Publicado 2015

A Rapamycin-Activated Caspase 9-Based Suicide Gene

por Stavrou, Maria, Philip, Brian, Traynor-White, Charlotte, Davis, Christopher G., Onuoha, Shimobi, Cordoba, Shaun, Thomas, Simon, Pule, Martin
Publicado 2018

A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency

por Leach, Adam, Ilca, F. Tudor, Akbar, Zulaikha, Ferrari, Mathieu, Bentley, Emma M., Mattiuzzo, Giada, Onuoha, Shimobi, Miller, Ami, Ali, Hanif, Rabbitts, Terence H.
Publicado 2021

Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis

por Ferrari, Mathieu, Onuoha, Shimobi C., Fossati-Jimack, Liliane, Nerviani, Alessandra, Alves, Pedro L., Pagani, Sara, Deantonio, Cecilia, Colombo, Federico, Santoro, Claudio, Sblattero, Daniele, Pitzalis, Costantino
Publicado 2021

A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats

por Nannini, Francesco, Parekh, Farhaan, Wawrzyniecka, Patrycja, Mekkaoui, Leila, Righi, Matteo, Dastjerdi, Fatemeh V., Yeung, Jenny, Roddie, Claire, Bai, Yuchen, Ma, Biao, Ferrari, Mathieu, Onuoha, Shimobi, Chester, Kerry, Pule, Martin
Publicado 2020

Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments

por Nannini, Francesco, Senicar, Lenart, Parekh, Farhaan, Kong, Khai J., Kinna, Alexander, Bughda, Reyisa, Sillibourne, James, Hu, Xihao, Ma, Biao, Bai, Yuchen, Ferrari, Mathieu, Pule, Martin A., Onuoha, Shimobi C.
Publicado 2020

Tunable control of CAR T cell activity through tetracycline mediated disruption of protein–protein interaction

por Hotblack, Alastair, Kokalaki, Evangelia K., Palton, Morgan J., Cheung, Gordon Weng-Kit, Williams, Iwan P., Manzoor, Somayya, Grothier, Thomas I., Piapi, Alice, Fiaccadori, Valeria, Wawrzyniecka, Patrycja, Roddy, Harriet A., Agliardi, Giulia, Roddie, Claire, Onuoha, Shimobi, Thomas, Simon, Cordoba, Shaun, Pule, Martin
Publicado 2021

AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies

por Meyer, Steffen, Woodward, Martin, Hertel, Christina, Vlaicu, Philip, Haque, Yasmin, Kärner, Jaanika, Macagno, Annalisa, Onuoha, Shimobi C., Fishman, Dmytro, Peterson, Hedi, Metsküla, Kaja, Uibo, Raivo, Jäntti, Kirsi, Hokynar, Kati, Wolff, Anette S.B., Krohn, Kai, Ranki, Annamari, Peterson, Pärt, Kisand, Kai, Hayday, Adrian
Publicado 2016

Characterization of a Novel ACE2-Based Therapeutic with Enhanced Rather than Reduced Activity against SARS-CoV-2 Variants

por Ferrari, Mathieu, Mekkaoui, Leila, Ilca, F. Tudor, Akbar, Zulaikha, Bughda, Reyisa, Lamb, Katarina, Ward, Katarzyna, Parekh, Farhaan, Karattil, Rajeev, Allen, Christopher, Wu, Philip, Baldan, Vania, Mattiuzzo, Giada, Bentley, Emma M., Takeuchi, Yasuhiro, Sillibourne, James, Datta, Preeta, Kinna, Alexander, Pule, Martin, Onuoha, Shimobi C.
Publicado 2021

Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy

por Lee, Lydia, Lim, Wen Chean, Galas-Filipowicz, Daria, Fung, Kent, Taylor, Julia, Patel, Dominic, Akbar, Zulaikha, Alvarez Mediavilla, Elena, Wawrzyniecka, Patrycja, Shome, Debarati, Reijmers, Rogier M, Gregg, Trillian, Wood, Leigh, Day, William, Cerec, Virginie, Ferrari, Mathieu, Thomas, Simon, Cordoba, Shaun, Onuoha, Shimobi, Khokhar, Nushmia, Peddareddigari, Vijay, Al-Hajj, Muhammad, Cavet, Jim, Zweegman, Sonja, Rodriguez-Justo, Manuel, Yong, Kwee, Pule, Martin, Popat, Rakesh
Publicado 2023

CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial

por Cordoba, Shaun, Onuoha, Shimobi, Thomas, Simon, Pignataro, Daniela Soriano, Hough, Rachael, Ghorashian, Sara, Vora, Ajay, Bonney, Denise, Veys, Paul, Rao, Kanchan, Lucchini, Giovanna, Chiesa, Robert, Chu, Jan, Clark, Liz, Fung, Mei Mei, Smith, Koval, Peticone, Carlotta, Al-Hajj, Muhammad, Baldan, Vania, Ferrari, Mathieu, Srivastava, Saket, Jha, Ram, Arce Vargas, Frederick, Duffy, Kevin, Day, William, Virgo, Paul, Wheeler, Lucy, Hancock, Jeremy, Farzaneh, Farzin, Domning, Sabine, Zhang, Yiyun, Khokhar, Nushmia Z., Peddareddigari, Vijay G. R., Wynn, Robert, Pule, Martin, Amrolia, Persis J.
Publicado 2021