Transcriptomic Analysis of Respiratory Tissue and Cell Line Models to Examine Glycosylation Machinery during SARS-CoV-2 Infection

por Oommen, Anup, Cunningham, Stephen, Joshi, Lokesh
Publicado 2021

Transcriptomic Analysis of Glycosylation and Neuroregulatory Pathways in Rodent Models in Response to Psychedelic Molecules

por Oommen, Anup M., Roberts, Katherine J., Joshi, Lokesh, Cunningham, Stephen
Publicado 2023

An integrative network analysis framework for identifying molecular functions in complex disorders examining major depressive disorder as a test case

por Oommen, Anup Mammen, Cunningham, Stephen, O’Súilleabháin, Páraic S., Hughes, Brian M., Joshi, Lokesh
Publicado 2021

Sphingolipid Metabolic Pathway: An Overview of Major Roles Played in Human Diseases

por Pralhada Rao, Raghavendra, Vaidyanathan, Nanditha, Rengasamy, Mathiyazhagan, Mammen Oommen, Anup, Somaiya, Neeti, Jagannath, M. R.
Publicado 2013

A novel GPR40 agonist, CNX-011-67, suppresses glucagon secretion in pancreatic islets under chronic glucolipotoxic conditions in vitro

por Verma, Mahesh Kumar, Biswas, Sanghamitra, Chandravanshi, Bhawna, Neelima, Korrapati, Oommen, Anup M, Jagannath, Madanahalli R, Somesh, Baggavalli P
Publicado 2014

Modulation of de novo purine biosynthesis leads to activation of AMPK and results in improved glucose handling and insulin sensitivity

por Sadasivan, Satish Kumar, Vasamsetti, Balamuralikrishna, Singh, Jaideep, Siddaraju, Nethra, Khan, Khaiser Mehdi, Oommen, Anup Mammen, Jagannath, Madanalli R, Rao, Raghavendra Pralhada
Publicado 2014

Fast food diet with CCl4 micro-dose induced hepatic-fibrosis –a novel animal model

por Chheda, Tarak K, Shivakumar, Pratibha, Sadasivan, Satish Kumar, Chanderasekharan, Harish, Moolemath, Yogananda, Oommen, Anup M, Madanahalli, Jagannath R, Marikunte, Venkataranganna V
Publicado 2014

Integrated analysis of chronic lipotoxicity on muscle metabolism and stress and its reversal by antioxidants

por Verma, Mahesh Kumar, Yateesh, Aggunda Nagaraju, Smitha, Rachapalli, Neelima, Korrapati, Pallavi, Puttrevana M, Reddy, Madhusudhan, Poornima, Jayaram, Oommen, Anup M, Jagannath, Madanahalli R, Somesh, Baggavalli P
Publicado 2014

Developing an in vitro screening assay platform for evaluation of antifibrotic drugs using precision-cut liver slices

por Sadasivan, Satish Kumar, Siddaraju, Nethra, Khan, Khaiser Mehdi, Vasamsetti, Balamuralikrishna, Kumar, Nimisha R, Haridas, Vibha, Reddy, Madhusudhan B, Baggavalli, Somesh, Oommen, Anup M, Pralhada Rao, Raghavendra
Publicado 2014

Blood Metabolite Signature of Metabolic Syndrome Implicates Alterations in Amino Acid Metabolism: Findings from the Baltimore Longitudinal Study of Aging (BLSA) and the Tsuruoka Me...

por Roberts, Jackson A., Varma, Vijay R., Huang, Chiung-Wei, An, Yang, Oommen, Anup, Tanaka, Toshiko, Ferrucci, Luigi, Elango, Palchamy, Takebayashi, Toru, Harada, Sei, Iida, Miho, Thambisetty, Madhav
Publicado 2020

Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress

por Verma, Mahesh Kumar, Yateesh, Aggunda Nagaraju, Neelima, Korrapati, Pawar, Niketa, Sandhya, Kandoor, Poornima, Jayaram, Lakshmi, Mudigere N, Yogeshwari, Sivakumaran, Pallavi, Puttrevana M, Oommen, Anup M, Somesh, Baggavalli P, Jagannath, Madanahalli R
Publicado 2014

Activation of GPR40 attenuates chronic inflammation induced impact on pancreatic β-cells health and function

por Verma, Mahesh Kumar, Sadasivuni, Manoj Kumar, Yateesh, Aggunda N, Neelima, Korrapati, Mrudula, Srikanth, Reddy, Madhusudhan, Smitha, Rachapalli, Biswas, Sanghamitra, Chandravanshi, Bhawna, Pallavi, Puttrevana M, Oommen, Anup M, Jagannath, Madanahalli R, Somesh, Baggavalli B
Publicado 2014

Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study

por Mahajan, Uma V., Varma, Vijay R., Griswold, Michael E., Blackshear, Chad T., An, Yang, Oommen, Anup M., Varma, Sudhir, Troncoso, Juan C., Pletnikova, Olga, O’Brien, Richard, Hohman, Timothy J., Legido-Quigley, Cristina, Thambisetty, Madhav
Publicado 2020

Correction: Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic st...

por Mahajan, Uma V., Varma, Vijay R., Griswold, Michael E., Blackshear, Chad T., An, Yang, Oommen, Anup M., Varma, Sudhir, Troncoso, Juan C., Pletnikova, Olga, O’Brien, Richard, Hohman, Timothy J., Legido-Quigley, Cristina, Thambisetty, Madhav
Publicado 2020

CNX-011-67, a novel GPR40 agonist, enhances glucose responsiveness, insulin secretion and islet insulin content in n-STZ rats and in islets from type 2 diabetic patients

por Sunil, Venkategowda, Verma, Mahesh Kumar, Oommen, Anup M, Sadasivuni, Manojkumar, Singh, Jaideep, Vijayraghav, Dasarahalli N, Chandravanshi, Bhawna, Shetty, Jayalaxmi, Biswas, Sanghamitra, Dandu, Anilkumar, Moolemath, Yoganand, Venkataranganna, Marikunte V, Somesh, Baggavalli P, Jagannath, Madanahalli R
Publicado 2014

Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity

por Somesh, Baggavalli P, Verma, Mahesh Kumar, Sadasivuni, Manoj Kumar, Mammen-Oommen, Anup, Biswas, Sanghamitra, Shilpa, Pavagada C, Reddy, Ashok Kumar, Yateesh, Aggunda N, Pallavi, Puttrevana M, Nethra, Siddaraju, Smitha, Rachapalli, Neelima, Korrapati, Narayanan, Usha, Jagannath, Madanahalli R
Publicado 2013

Abnormal brain cholesterol homeostasis in Alzheimer’s disease—a targeted metabolomic and transcriptomic study

por Varma, Vijay R., Büşra Lüleci, H., Oommen, Anup M., Varma, Sudhir, Blackshear, Chad T., Griswold, Michael E., An, Yang, Roberts, Jackson A., O’Brien, Richard, Pletnikova, Olga, Troncoso, Juan C., Bennett, David A., Çakır, Tunahan, Legido-Quigley, Cristina, Thambisetty, Madhav
Publicado 2021

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

por Logue, Susan E., McGrath, Eoghan P., Cleary, Patricia, Greene, Stephanie, Mnich, Katarzyna, Almanza, Aitor, Chevet, Eric, Dwyer, Róisín M., Oommen, Anup, Legembre, Patrick, Godey, Florence, Madden, Emma C., Leuzzi, Brian, Obacz, Joanna, Zeng, Qingping, Patterson, John B., Jäger, Richard, Gorman, Adrienne M., Samali, Afshin
Publicado 2018

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study

por Varma, Vijay R., Oommen, Anup M., Varma, Sudhir, Casanova, Ramon, An, Yang, Andrews, Ryan M., O’Brien, Richard, Pletnikova, Olga, Troncoso, Juan C., Toledo, Jon, Baillie, Rebecca, Arnold, Matthias, Kastenmueller, Gabi, Nho, Kwangsik, Doraiswamy, P. Murali, Saykin, Andrew J., Kaddurah-Daouk, Rima, Legido-Quigley, Cristina, Thambisetty, Madhav
Publicado 2018

Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study

por Varma, Vijay R., Wang, Youjin, An, Yang, Varma, Sudhir, Bilgel, Murat, Doshi, Jimit, Legido-Quigley, Cristina, Delgado, João C., Oommen, Anup M., Roberts, Jackson A., Wong, Dean F., Davatzikos, Christos, Resnick, Susan M., Troncoso, Juan C., Pletnikova, Olga, O’Brien, Richard, Hak, Eelko, Baak, Brenda N., Pfeiffer, Ruth, Baloni, Priyanka, Mohmoudiandehkordi, Siamak, Nho, Kwangsik, Kaddurah-Daouk, Rima, Bennett, David A., Gadalla, Shahinaz M., Thambisetty, Madhav
Publicado 2021