Introducing the Stem Cell ASCL2 Reporter STAR into Intestinal Organoids

por Heinz, Maria C., Oost, Koen C., Snippert, Hugo J.G.
Publicado 2020

Integrative multi‐omics analysis of intestinal organoid differentiation

por Lindeboom, Rik GH, van Voorthuijsen, Lisa, Oost, Koen C, Rodríguez‐Colman, Maria J, Luna‐Velez, Maria V, Furlan, Cristina, Baraille, Floriane, Jansen, Pascal WTC, Ribeiro, Agnès, Burgering, Boudewijn MT, Snippert, Hugo J, Vermeulen, Michiel
Publicado 2018

Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity

por Melhem, Hassan, Kaya, Berna, Kaymak, Tanay, Wuggenig, Philipp, Flint, Emilio, Roux, Julien, Oost, Koen C., Cavelti-Weder, Claudia, Balmer, Maria L., Walser, Jean-Claude, Morales, Rodrigo A., Riedel, Christian U., Liberali, Prisca, Villablanca, Eduardo J., Niess, Jan Hendrik
Publicado 2022

Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene

por Oost, Koen C., van Voorthuijsen, Lisa, Fumagalli, Arianna, Lindeboom, Rik G.H., Sprangers, Joep, Omerzu, Manja, Rodriguez-Colman, Maria J., Heinz, Maria C., Verlaan-Klink, Ingrid, Maurice, Madelon M., Burgering, Boudewijn M.T., van Rheenen, Jacco, Vermeulen, Michiel, Snippert, Hugo J.G.
Publicado 2018

Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage

por Heinz, Maria C., Peters, Niek A., Oost, Koen C., Lindeboom, Rik G.H., van Voorthuijsen, Lisa, Fumagalli, Arianna, van der Net, Mirjam C., de Medeiros, Gustavo, Hageman, Joris H., Verlaan-Klink, Ingrid, Borel Rinkes, Inne H.M., Liberali, Prisca, Gloerich, Martijn, van Rheenen, Jacco, Vermeulen, Michiel, Kranenburg, Onno, Snippert, Hugo J.G.
Publicado 2022

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer

por Fumagalli, Arianna, Oost, Koen C., Kester, Lennart, Morgner, Jessica, Bornes, Laura, Bruens, Lotte, Spaargaren, Lisa, Azkanaz, Maria, Schelfhorst, Tim, Beerling, Evelyne, Heinz, Maria C., Postrach, Daniel, Seinstra, Danielle, Sieuwerts, Anieta M., Martens, John W.M., van der Elst, Stefan, van Baalen, Martijn, Bhowmick, Debajit, Vrisekoop, Nienke, Ellenbroek, Saskia I.J., Suijkerbuijk, Saskia J.E., Snippert, Hugo J., van Rheenen, Jacco
Publicado 2020

Retrograde movements determine effective stem cell numbers in the intestine

por Azkanaz, Maria, Corominas-Murtra, Bernat, Ellenbroek, Saskia I.J., Bruens, Lotte, Webb, Anna T., Laskaris, Dimitrios, Oost, Koen C., Lafirenze, Simona J.A., Annusver, Karl, Messal, Hendrik A., Iqbal, Sharif, Flanagan, Dustin J., Huels, David J., Rojas-Rodríguez, Felipe, Vizoso, Miguel, Kasper, Maria, Sansom, Owen J., Snippert, Hugo J., Liberali, Prisca, Simons, Benjamin D., Katajisto, Pekka, Hannezo, Edouard, van Rheenen, Jacco
Publicado 2022

Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns

por Bollen, Yannik, Stelloo, Ellen, van Leenen, Petra, van den Bos, Myrna, Ponsioen, Bas, Lu, Bingxin, van Roosmalen, Markus J., Bolhaqueiro, Ana C. F., Kimberley, Christopher, Mossner, Maximilian, Cross, William C. H., Besselink, Nicolle J. M., van der Roest, Bastiaan, Boymans, Sander, Oost, Koen C., de Vries, Sippe G., Rehmann, Holger, Cuppen, Edwin, Lens, Susanne M. A., Kops, Geert J. P. L., Kloosterman, Wigard P., Terstappen, Leon W. M. M., Barnes, Chris P., Sottoriva, Andrea, Graham, Trevor A., Snippert, Hugo J. G.
Publicado 2021