Computational modeling of stem and progenitor cell kinetics identifies plausible hematopoietic lineage hierarchies

por Bast, Lisa, Buck, Michèle C., Hecker, Judith S., Oostendorp, Robert A.J., Götze, Katharina S., Marr, Carsten
Publicado 2021

In vivo hematopoietic Myc activation directs a transcriptional signature in endothelial cells within the bone marrow microenvironment

por Franke, Katharina, Vilne, Baiba, da Costa, Olivia Prazeres, Rudelius, Martina, Peschel, Christian, Oostendorp, Robert A.J., Keller, Ulrich
Publicado 2015

Corrigendum: Efficient in vitro generation of IL-22-secreting ILC3 from CD34+ hematopoietic progenitors in a human mesenchymal stem cell niche

por Bennstein, Sabrina B., Weinhold, Sandra, Degistirici, Özer, Oostendorp, Robert A. J., Raba, Katharina, Kögler, Gesine, Meisel, Roland, Walter, Lutz, Uhrberg, Markus
Publicado 2023

Efficient In Vitro Generation of IL-22-Secreting ILC3 From CD34(+) Hematopoietic Progenitors in a Human Mesenchymal Stem Cell Niche

por Bennstein, Sabrina B., Weinhold, Sandra, Degistirici, Özer, Oostendorp, Robert A. J., Raba, Katharina, Kögler, Gesine, Meisel, Roland, Walter, Lutz, Uhrberg, Markus
Publicado 2021

The Hematopoietic Bone Marrow Niche Ecosystem

por Fröbel, Julia, Landspersky, Theresa, Percin, Gülce, Schreck, Christina, Rahmig, Susann, Ori, Alessandro, Nowak, Daniel, Essers, Marieke, Waskow, Claudia, Oostendorp, Robert A. J.
Publicado 2021

Kindlin-3–mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells

por Ruppert, Raphael, Moser, Markus, Sperandio, Markus, Rognoni, Emanuel, Orban, Martin, Liu, Wen-Hsin, Schulz, Ansgar S., Oostendorp, Robert A.J., Massberg, Steffen, Fässler, Reinhard
Publicado 2015

Inferring Gene Networks in Bone Marrow Hematopoietic Stem Cell-Supporting Stromal Niche Populations

por Desterke, Christophe, Petit, Laurence, Sella, Nadir, Chevallier, Nathalie, Cabeli, Vincent, Coquelin, Laura, Durand, Charles, Oostendorp, Robert A.J., Isambert, Hervé, Jaffredo, Thierry, Charbord, Pierre
Publicado 2020

Murine Oncostatin M Has Opposing Effects on the Proliferation of OP9 Bone Marrow Stromal Cells and NIH/3T3 Fibroblasts Signaling through the OSMR

por Jakob, Lena, Müller, Tony Andreas, Rassner, Michael, Kleinfelder, Helen, Veratti, Pia, Mitschke, Jan, Miething, Cornelius, Oostendorp, Robert A. J., Pfeifer, Dietmar, Waterhouse, Miguel, Duyster, Justus
Publicado 2021

Bone marrow stromal cells from MDS and AML patients show increased adipogenic potential with reduced Delta-like-1 expression

por Weickert, Marie-Theresa, Hecker, Judith S., Buck, Michèle C., Schreck, Christina, Rivière, Jennifer, Schiemann, Matthias, Schallmoser, Katharina, Bassermann, Florian, Strunk, Dirk, Oostendorp, Robert A. J., Götze, Katharina S.
Publicado 2021

Distinct Stromal Cell Factor Combinations Can Separately Control Hematopoietic Stem Cell Survival, Proliferation, and Self-Renewal

por Wohrer, Stefan, Knapp, David J.H.F., Copley, Michael R., Benz, Claudia, Kent, David G., Rowe, Keegan, Babovic, Sonja, Mader, Heidi, Oostendorp, Robert A.J., Eaves, Connie J.
Publicado 2014

Cathepsin K maintains the compartment of bone marrow T lymphocytes in vivo

por Hausinger, Renate, Hackl, Marianne, Jardon Alvarez, Ana, Kehr, Miriam, Romero Marquez, Sandra, Hettler, Franziska, Kehr, Christian, Grziwok, Sandra, Schreck, Christina, Peschel, Christian, Istvánffy, Rouzanna, Oostendorp, Robert A. J.
Publicado 2021

Comparative analysis of extracellular vesicle isolation methods from human AML bone marrow cells and AML cell lines

por Lang, Jonas B., Buck, Michèle C., Rivière, Jennifer, Stambouli, Oumaima, Sachenbacher, Ken, Choudhary, Purva, Dietz, Hendrik, Giebel, Bernd, Bassermann, Florian, Oostendorp, Robert A. J., Götze, Katharina S., Hecker, Judith S.
Publicado 2022

Secreted factors from mouse embryonic fibroblasts maintain repopulating function of single cultured hematopoietic stem cells

por Marquez, Romero, Hettler, Franziska, Hausinger, Renate, Schreck, Christina, Landspersky, Theresa, Henkel, Lynette, Angerpointner, Corinne, Demir, Ihsan E., Schiemann, Matthias, Bassermann, Florian, Götze, Katharina S., Istvánffy, Rouzanna, Oostendorp, Robert A.J.
Publicado 2020

Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression

por Klein, Claudius, Zwick, Anabel, Kissel, Sandra, Forster, Christine Ulrike, Pfeifer, Dietmar, Follo, Marie, Illert, Anna Lena, Decker, Sarah, Benkler, Thomas, Pahl, Heike, Oostendorp, Robert A.J., Aumann, Konrad, Duyster, Justus, Dierks, Christine
Publicado 2016

Progressive disruption of hematopoietic architecture from clonal hematopoiesis to MDS

por Buck, Michèle C., Bast, Lisa, Hecker, Judith S., Rivière, Jennifer, Rothenberg-Thurley, Maja, Vogel, Luisa, Wang, Dantong, Andrä, Immanuel, Theis, Fabian J., Bassermann, Florian, Metzeler, Klaus H., Oostendorp, Robert A.J., Marr, Carsten, Götze, Katharina S.
Publicado 2023

Stroma-Derived Connective Tissue Growth Factor Maintains Cell Cycle Progression and Repopulation Activity of Hematopoietic Stem Cells In Vitro

por Istvánffy, Rouzanna, Vilne, Baiba, Schreck, Christina, Ruf, Franziska, Pagel, Charlotta, Grziwok, Sandra, Henkel, Lynette, Prazeres da Costa, Olivia, Berndt, Johannes, Stümpflen, Volker, Götze, Katharina S., Schiemann, Matthias, Peschel, Christian, Mewes, Hans-Werner, Oostendorp, Robert A.J.
Publicado 2015

Extra-hematopoietic immunomodulatory role of the guanine-exchange factor DOCK2

por Scharler, Cornelia, Poupardin, Rodolphe, Ebner-Peking, Patricia, Wolf, Martin, Schreck, Christina, Brachtl, Gabriele, Cronemberger Andrade, Andre, Krisch, Linda, Daheron, Laurence, Schallmoser, Katharina, Jürchott, Karsten, Küchler, Judit, Stachelscheid, Harald, Volk, Hans-Dieter, Oostendorp, Robert A. J., Strunk, Dirk
Publicado 2022

Osteoprogenitor SFRP1 prevents exhaustion of hematopoietic stem cells via PP2A-PR72/130-mediated regulation of p300

por Hettler, Franziska, Schreck, Christina, Marquez, Sandra Romero, Engleitner, Thomas, Vilne, Baiba, Landspersky, Theresa, Weidner, Heike, Hausinger, Renate, Mishra, Ritu, Oellinger, Rupert, Rauner, Martina, Naumann, Ronald, Peschel, Christian, Bassermann, Florian, Rad, Roland, Istvanffy, Rouzanna, Oostendorp, Robert A.J.
Publicado 2022

Ly6D(+)Siglec-H(+) precursors contribute to conventional dendritic cells via a Zbtb46(+)Ly6D(+) intermediary stage

por Lutz, Konstantin, Musumeci, Andrea, Sie, Christopher, Dursun, Ezgi, Winheim, Elena, Bagnoli, Johannes, Ziegenhain, Christoph, Rausch, Lisa, Bergen, Volker, Luecken, Malte D., Oostendorp, Robert A. J., Schraml, Barbara U., Theis, Fabian J., Enard, Wolfgang, Korn, Thomas, Krug, Anne B.
Publicado 2022

Azacitidine combined with the selective FLT3 kinase inhibitor crenolanib disrupts stromal protection and inhibits expansion of residual leukemia-initiating cells in FLT3-ITD AML wi...

por Garz, Anne-Kathrin, Wolf, Saskia, Grath, Sonja, Gaidzik, Verena, Habringer, Stefan, Vick, Binje, Rudelius, Martina, Ziegenhain, Christoph, Herold, Sylvia, Weickert, Marie-Theresa, Smets, Martha, Peschel, Christian, Oostendorp, Robert A.J., Bultmann, Sebastian, Jeremias, Irmela, Thiede, Christian, Döhner, Konstanze, Keller, Ulrich, Götze, Katharina S.
Publicado 2017