Melanoma response to anti-PD-L1 immunotherapy requires JAK1 signaling, but not JAK2

por Luo, Na, Formisano, Luigi, Gonzalez-Ericsson, Paula I., Sanchez, Violeta, Dean, Phillip T., Opalenik, Susan R., Sanders, Melinda E., Cook, Rebecca S., Arteaga, Carlos L., Johnson, Douglas B., Balko, Justin M.
Publicado 2018

DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer

por Luo, Na, Nixon, Mellissa J., Gonzalez-Ericsson, Paula I., Sanchez, Violeta, Opalenik, Susan R., Li, Huili, Zahnow, Cynthia A., Nickels, Michael L., Liu, Fei, Tantawy, Mohammed N., Sanders, Melinda E., Manning, H. Charles, Balko, Justin M.
Publicado 2018

Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress escape in breast cancer

por Hanna, Ann, Nixon, Mellissa J., Estrada, M. Valeria, Sanchez, Violeta, Sheng, Quanhu, Opalenik, Susan R., Toren, Abigail L., Bauer, Joshua, Owens, Phillip, Mason, Frank M., Cook, Rebecca S., Sanders, Melinda E., Arteaga, Carlos L., Balko, Justin M.
Publicado 2022

MEK activation modulates glycolysis and supports suppressive myeloid cells in TNBC

por Franklin, Derek A., Sharick, Joe T., Ericsson-Gonzalez, Paula I., Sanchez, Violeta, Dean, Phillip T., Opalenik, Susan R., Cairo, Stefano, Judde, Jean-Gabriel, Lewis, Michael T., Chang, Jenny C., Sanders, Melinda E., Cook, Rebecca S., Skala, Melissa C., Bordeaux, Jennifer, Orozco Bender, Jehovana, Vaupel, Christine, Geiss, Gary, Hinerfeld, Douglas, Balko, Justin M.
Publicado 2020

Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy

por Johnson, Douglas B., Estrada, Monica V., Salgado, Roberto, Sanchez, Violeta, Doxie, Deon B., Opalenik, Susan R., Vilgelm, Anna E., Feld, Emily, Johnson, Adam S., Greenplate, Allison R., Sanders, Melinda E., Lovly, Christine M., Frederick, Dennie T., Kelley, Mark C., Richmond, Ann, Irish, Jonathan M., Shyr, Yu, Sullivan, Ryan J., Puzanov, Igor, Sosman, Jeffrey A., Balko, Justin M.
Publicado 2016