The complex biology of aryl hydrocarbon receptor activation in cancer and beyond

por Opitz, Christiane A., Holfelder, Pauline, Prentzell, Mirja Tamara, Trump, Saskia
Publicado 2023

Isoform Diversity of Giant Proteins in Relation to Passive and Active Contractile Properties of Rabbit Skeletal Muscles

por Prado, Lucas G., Makarenko, Irina, Andresen, Christian, Krüger, Martina, Opitz, Christiane A., Linke, Wolfgang A.
Publicado 2005

Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma

por Mohapatra, Soumya R., Sadik, Ahmed, Tykocinski, Lars-Oliver, Dietze, Jørn, Poschet, Gernot, Heiland, Ines, Opitz, Christiane A.
Publicado 2019

Device-Controlled Microcondensation for Spatially Confined On-Tissue Digests in MALDI Imaging of N-Glycans

por Fülöp, Annabelle, Marsching, Christian, Barka, Frederik, Ucal, Yasemin, Pfänder, Pauline, Opitz, Christiane A., Barka, Günes, Hopf, Carsten
Publicado 2022

The Indoleamine-2,3-Dioxygenase (IDO) Inhibitor 1-Methyl-D-tryptophan Upregulates IDO1 in Human Cancer Cells

por Opitz, Christiane A., Litzenburger, Ulrike M., Opitz, Uta, Sahm, Felix, Ochs, Katharina, Lutz, Christian, Wick, Wolfgang, Platten, Michael
Publicado 2011

The therapeutic potential of targeting tryptophan catabolism in cancer

por Opitz, Christiane A., Somarribas Patterson, Luis F., Mohapatra, Soumya R., Dewi, Dyah L., Sadik, Ahmed, Platten, Michael, Trump, Saskia
Publicado 2019

The TSC Complex-mTORC1 Axis: From Lysosomes to Stress Granules and Back

por Rehbein, Ulrike, Prentzell, Mirja Tamara, Cadena Sandoval, Marti, Heberle, Alexander Martin, Henske, Elizabeth P., Opitz, Christiane A., Thedieck, Kathrin
Publicado 2021

Constitutive Expression of the Immunosuppressive Tryptophan Dioxygenase TDO2 in Glioblastoma Is Driven by the Transcription Factor C/EBPβ

por Kudo, Takumi, Prentzell, Mirja T., Mohapatra, Soumya R., Sahm, Felix, Zhao, Zhongliang, Grummt, Ingrid, Wick, Wolfgang, Opitz, Christiane A., Platten, Michael, Green, Edward W.
Publicado 2020

Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis

por Lercher, Alexander, Popa, Alexandra M., Viczenczova, Csilla, Kosack, Lindsay, Klavins, Kristaps, Agerer, Benedikt, Opitz, Christiane A., Lanz, Tobias V., Platten, Michael, Bergthaler, Andreas
Publicado 2020

Resistance Exercise Reduces Kynurenine Pathway Metabolites in Breast Cancer Patients Undergoing Radiotherapy

por Zimmer, Philipp, Schmidt, Martina E., Prentzell, Mirja Tamara, Berdel, Bianca, Wiskemann, Joachim, Kellner, Karl Heinz, Debus, Jürgen, Ulrich, Cornelia, Opitz, Christiane A., Steindorf, Karen
Publicado 2019

Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production

por Mohapatra, Soumya R., Sadik, Ahmed, Sharma, Suraj, Poschet, Gernot, Gegner, Hagen M., Lanz, Tobias V., Lucarelli, Philippe, Klingmüller, Ursula, Platten, Michael, Heiland, Ines, Opitz, Christiane A.
Publicado 2021

Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies

por Rabe, Jan-Hinrich, A. Sammour, Denis, Schulz, Sandra, Munteanu, Bogdan, Ott, Martina, Ochs, Katharina, Hohenberger, Peter, Marx, Alexander, Platten, Michael, Opitz, Christiane A., Ory, Daniel S., Hopf, Carsten
Publicado 2018

Author Correction: Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies

por Rabe, Jan-Hinrich, Sammour, Denis A., Schulz, Sandra, Munteanu, Bogdan, Ott, Martina, Ochs, Katharina, Hohenberger, Peter, Marx, Alexander, Platten, Michael, Opitz, Christiane A., Ory, Daniel S., Hopf, Carsten
Publicado 2018

Comparative Assessment of Quantification Methods for Tumor Tissue Phosphoproteomics

por Zhang, Yang, Dreyer, Benjamin, Govorukhina, Natalia, Heberle, Alexander M., Končarević, Saša, Krisp, Christoph, Opitz, Christiane A., Pfänder, Pauline, Bischoff, Rainer, Schlüter, Hartmut, Kwiatkowski, Marcel, Thedieck, Kathrin, Horvatovich, Peter L.
Publicado 2022

The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner

por Heberle, Alexander Martin, Razquin Navas, Patricia, Langelaar-Makkinje, Miriam, Kasack, Katharina, Sadik, Ahmed, Faessler, Erik, Hahn, Udo, Marx-Stoelting, Philip, Opitz, Christiane A, Sers, Christine, Heiland, Ines, Schäuble, Sascha, Thedieck, Kathrin
Publicado 2019

Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes

por Solvay, Marie, Holfelder, Pauline, Klaessens, Simon, Pilotte, Luc, Stroobant, Vincent, Lamy, Juliette, Naulaerts, Stefan, Spillier, Quentin, Frédérick, Raphaël, De Plaen, Etienne, Sers, Christine, Opitz, Christiane A, Van den Eynde, Benoit J, Zhu, Jingjing
Publicado 2023

Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation

por Adam, Isabell, Dewi, Dyah L., Mooiweer, Joram, Sadik, Ahmed, Mohapatra, Soumya R., Berdel, Bianca, Keil, Melanie, Sonner, Jana K., Thedieck, Kathrin, Rose, Adam J., Platten, Michael, Heiland, Ines, Trump, Saskia, Opitz, Christiane A.
Publicado 2018

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR

por Litzenburger, Ulrike M., Opitz, Christiane A., Sahm, Felix, Rauschenbach, Katharina J., Trump, Saskia, Winter, Marcus, Ott, Martina, Ochs, Katharina, Lutz, Christian, Liu, Xiangdong, Anastasov, Natasa, Lehmann, Irina, Höfer, Thomas, von Deimling, Andreas, Wick, Wolfgang, Platten, Michael
Publicado 2014

Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis

por Nothdurft, Silke, Thumser-Henner, Clotilde, Breitenbücher, Frank, Okimoto, Ross A., Dorsch, Madeleine, Opitz, Christiane A., Sadik, Ahmed, Esser, Charlotte, Hölzel, Michael, Asthana, Saurabh, Forster, Jan, Beisser, Daniela, Kalmbach, Sophie, Grüner, Barbara M., Bivona, Trever G., Schramm, Alexander, Schuler, Martin
Publicado 2020

ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition

por Bakr, Ali, Hey, Joschka, Sigismondo, Gianluca, Liu, Chun-Shan, Sadik, Ahmed, Goyal, Ashish, Cross, Alice, Iyer, Ramya Lakshmana, Müller, Patrick, Trauernicht, Max, Breuer, Kersten, Lutsik, Pavlo, Opitz, Christiane A, Krijgsveld, Jeroen, Weichenhan, Dieter, Plass, Christoph, Popanda, Odilia, Schmezer, Peter
Publicado 2021