The impact of immunogenicity on therapeutic antibody pharmacokinetics: A preclinical evaluation of the effect of immune complex formation and antibody effector function on clearanc...

por Opolka-Hoffmann, Eugenia, Jordan, Gregor, Otteneder, Michael, Kieferle, Robin, Lechmann, Martin, Winter, Gerhard, Staack, Roland F.
Publicado 2021

Enhanced immunogenic potential of cancer immunotherapy antibodies in human IgG1 transgenic mice

por Egli, Jerome, Heiler, Stefan, Weber, Felix, Steiner, Guido, Schwandt, Timo, Bray-French, Katharine, Klein, Christian, Fenn, Sebastian, Lotz, Gregor P., Opolka-Hoffmann, Eugenia, Kraft, Thomas E., Petersen, Laetitia, Moser, Rebecca, DeGeer, Jonathan, Siegel, Michel, Finke, Daniela, Bessa, Juliana, Iglesias, Antonio
Publicado 2022