IL-1-driven cartilage and bone destruction are dependent on Toll-like receptor (TLR) 4, but not TLR2

por Abdollahi-Roodsaz, S, Joosten, LAB, Roelofs, MF, Helsen, MMA, Oppers-Walgreen, B, Arndtz, CHM, Radstake, TRDJ, van den Berg, WB
Publicado 2005

IL-18 expression in synovial biopsies of patients with active rheumatoid arthritis is associated with enhanced levels of both IL-1 and TNFα

por Joosten, LAB, Barrera, P, Lubberts, E, Blom, AB, Oppers-Walgreen, B, van den Bersselaa, LAM, van den Berg, WB
Publicado 2002

Local IL-18 gene transfer prevents severe joint destruction in murine collagen-induced arthritis by induction of IL-4 and osteoprotegerin

por Joosten, LAB, Smeets, RL, Koenders, MI, Helsen, MMA, Oppers-Walgreen, B, van de Loo, FAJ, Lubberts, E, van den Berg, WB
Publicado 2005

Neutralizing synovial RANKL by local OPG gene therapy in collagen-induced arthritis prevents cartilage erosion through induction of a non-destructive type 2 synovitis

por Lubberts, E, Koenders, MI, Oppers-Walgreen, B, Wagenmans, M, van den Bersselaar, L, Joosten, LAB, Schurr, J, Kolls, JK, van den Berg, WB
Publicado 2004