FGF21 increases water intake, urine output and blood pressure in rats

por Turner, Tod, Chen, Xian, Zahner, Matthew, Opsahl, Alan, DeMarco, George, Boucher, Magalie, Goodwin, Bryan, Perreault, Mylène
Publicado 2018

A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equival...

por St. Andre, Michael, Johnson, Mark, Bansal, Prashant N., Wellen, Jeremy, Robertson, Andrew, Opsahl, Alan, Burch, Peter M., Bialek, Peter, Morris, Carl, Owens, Jane
Publicado 2017

Postnatal PPARδ Activation and Myostatin Inhibition Exert Distinct yet Complimentary Effects on the Metabolic Profile of Obese Insulin-Resistant Mice

por Bernardo, Barbara L., Wachtmann, Timothy S., Cosgrove, Patricia G., Kuhn, Max, Opsahl, Alan C., Judkins, Kyle M., Freeman, Thomas B., Hadcock, John R., LeBrasseur, Nathan K.
Publicado 2010

Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition

por Roth Flach, Rachel J., Su, Chunyan, Bollinger, Eliza, Cortes, Christian, Robertson, Andrew W., Opsahl, Alan C., Coskran, Timothy M., Maresca, Kevin P., Keliher, Edmund J., Yates, Phillip D., Kim, Albert M., Kalgutkar, Amit S., Buckbinder, Leonard
Publicado 2019

Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems

por Ross, Trenton T., Crowley, Collin, Kelly, Kenneth L., Rinaldi, Anthony, Beebe, David A., Lech, Matthew P., Martinez, Robert V., Carvajal-Gonzalez, Santos, Boucher, Magalie, Hirenallur-Shanthappa, Dinesh, Morin, Jeffrey, Opsahl, Alan C., Vargas, Sarah R., Bence, Kendra K., Pfefferkorn, Jeffrey A., Esler, William P.
Publicado 2020

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

por Esquejo, Ryan M., Salatto, Christopher T., Delmore, Jake, Albuquerque, Bina, Reyes, Allan, Shi, Yuji, Moccia, Rob, Cokorinos, Emily, Peloquin, Matthew, Monetti, Mara, Barricklow, Jason, Bollinger, Eliza, Smith, Brennan K., Day, Emily A., Nguyen, Chuong, Geoghegan, Kieran F., Kreeger, John M., Opsahl, Alan, Ward, Jessica, Kalgutkar, Amit S., Tess, David, Butler, Lynne, Shirai, Norimitsu, Osborne, Timothy F., Steinberg, Gregory R., Birnbaum, Morris J., Cameron, Kimberly O., Miller, Russell A.
Publicado 2018