Cytoskeletal Remodelling as an Achilles’ Heel for Therapy Resistance in Melanoma

por Barreno, Adrian, Orgaz, Jose L.
Publicado 2022

What does not kill you makes you stronger: surviving anti-cancer therapies by cytoskeletal remodeling and Myosin II reactivation

por Orgaz, Jose L, Sanz-Moreno, Victoria
Publicado 2020

Modes of invasion during tumour dissemination

por Pandya, Pahini, Orgaz, Jose L., Sanz‐Moreno, Victoria
Publicado 2016

Actomyosin contractility and collective migration: may the force be with you

por Pandya, Pahini, Orgaz, Jose L, Sanz-Moreno, Victoria
Publicado 2017

CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion

por Farrugia, Aaron J., Rodríguez, Javier, Orgaz, Jose L., Lucas, María, Sanz-Moreno, Victoria, Calvo, Fernando
Publicado 2020

Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination

por Herraiz, Cecilia, Calvo, Fernando, Pandya, Pahini, Cantelli, Gaia, Rodriguez-Hernandez, Irene, Orgaz, Jose L., Kang, NaRa, Chu, Tinghine, Sahai, Erik, Sanz-Moreno, Victoria
Publicado 2015

TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination

por Cantelli, Gaia, Orgaz, Jose L., Rodriguez-Hernandez, Irene, Karagiannis, Panagiotis, Maiques, Oscar, Matias-Guiu, Xavier, Nestle, Frank O., Marti, Rosa M., Karagiannis, Sophia N., Sanz-Moreno, Victoria
Publicado 2015

A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma

por Maiques, Oscar, Fanshawe, Bruce, Crosas-Molist, Eva, Rodriguez-Hernandez, Irene, Volpe, Alessia, Cantelli, Gaia, Boehme, Lena, Orgaz, Jose L., Mardakheh, Faraz K., Sanz-Moreno, Victoria, Fruhwirth, Gilbert O.
Publicado 2021

Diverse matrix metalloproteinase functions regulate cancer amoeboid migration

por Orgaz, Jose L., Pandya, Pahini, Dalmeida, Rimple, Karagiannis, Panagiotis, Sanchez-Laorden, Berta, Viros, Amaya, Albrengues, Jean, Nestle, Frank O., Ridley, Anne J., Gaggioli, Cedric, Marais, Richard, Karagiannis, Sophia N., Sanz-Moreno, Victoria
Publicado 2014

Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance

por Orgaz, Jose L., Crosas-Molist, Eva, Sadok, Amine, Perdrix-Rosell, Anna, Maiques, Oscar, Rodriguez-Hernandez, Irene, Monger, Jo, Mele, Silvia, Georgouli, Mirella, Bridgeman, Victoria, Karagiannis, Panagiotis, Lee, Rebecca, Pandya, Pahini, Boehme, Lena, Wallberg, Fredrik, Tape, Chris, Karagiannis, Sophia N., Malanchi, Ilaria, Sanz-Moreno, Victoria
Publicado 2020

WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion

por Rodriguez-Hernandez, Irene, Maiques, Oscar, Kohlhammer, Leonie, Cantelli, Gaia, Perdrix-Rosell, Anna, Monger, Joanne, Fanshawe, Bruce, Bridgeman, Victoria L., Karagiannis, Sophia N., Penin, Rosa M., Marcolval, Joaquim, Marti, Rosa M., Matias-Guiu, Xavier, Fruhwirth, Gilbert O., Orgaz, Jose L., Malanchi, Ilaria, Sanz-Moreno, Victoria
Publicado 2020

CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells

por Samain, Remi, Maiques, Oscar, Monger, Joanne, Lam, Hoyin, Candido, Juliana, George, Samantha, Ferrari, Nicola, KohIhammer, Leonie, Lunetto, Sophia, Varela, Adrian, Orgaz, Jose L., Vilardell, Felip, Olsina, Jorge Juan, Matias-Guiu, Xavier, Sarker, Debashis, Biddle, Adrian, Balkwill, Frances R., Eyles, Jim, Wilkinson, Robert W., Kocher, Hemant M., Calvo, Fernando, Wells, Claire M., Sanz-Moreno, Victoria
Publicado 2023

Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment

por Georgouli, Mirella, Herraiz, Cecilia, Crosas-Molist, Eva, Fanshawe, Bruce, Maiques, Oscar, Perdrix, Anna, Pandya, Pahini, Rodriguez-Hernandez, Irene, Ilieva, Kristina M., Cantelli, Gaia, Karagiannis, Panagiotis, Mele, Silvia, Lam, Hoyin, Josephs, Debra H., Matias-Guiu, Xavier, Marti, Rosa M., Nestle, Frank O., Orgaz, Jose L., Malanchi, Ilaria, Fruhwirth, Gilbert O., Karagiannis, Sophia N., Sanz-Moreno, Victoria
Publicado 2019

Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer

por Aguilera, Óscar, González-Sancho, José Manuel, Zazo, Sandra, Rincón, Raúl, Fernández, Agustín F., Tapia, Olga, Canals, Francesc, Morte, Beatriz, Calvanese, Vincenzo, Orgaz, José L., Niell, Núria, Aguilar, Susana, Freije, José M., Graña, Osvaldo, Pisano, David G., Borrero, Aurea, Martínez-Useros, Javier, Jiménez, Benilde, Fraga, Mario F., García-Foncillas, Jesús, López-Otín, Carlos, Lafarga, Miguel, Rojo, Federico, Muñoz, Alberto
Publicado 2015