Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses

por Zvornicanin, Sarah N., Shaqra, Ala M., Huang, Qiuyu J., Ornelas, Elizabeth, Moghe, Mallika, Knapp, Mark, Moquin, Stephanie, Dovala, Dustin, Schiffer, Celia A., Kurt Yilmaz, Nese
Publicado 2023

A polyomavirus peptide binds to the capsid VP1 pore and has potent antiviral activity against BK and JC polyomaviruses

por Kane, Joshua R, Fong, Susan, Shaul, Jacob, Frommlet, Alexandra, Frank, Andreas O, Knapp, Mark, Bussiere, Dirksen E, Kim, Peter, Ornelas, Elizabeth, Cuellar, Carlos, Hyrina, Anastasia, Abend, Johanna R, Wartchow, Charles A
Publicado 2020

Harnessing the Anti-Cancer Natural Product Nimbolide for Targeted Protein Degradation

por Spradlin, Jessica N., Hu, Xirui, Ward, Carl C., Brittain, Scott M., Jones, Michael D., Ou, Lisha, To, Milton, Proudfoot, Andrew, Ornelas, Elizabeth, Woldegiorgis, Mikias, Olzmann, James A., Bussiere, Dirksen E., Thomas, Jason R., Tallarico, John A., McKenna, Jeffrey M., Schirle, Markus, Maimone, Thomas J., Nomura, Daniel K.
Publicado 2019

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

por Saldivia, Manuel, Fang, Eric, Ma, Xiaolei, Myburgh, Elmarie, Carnielli, Juliana B. T., Bower-Lepts, Christopher, Brown, Elaine, Ritchie, Ryan, Lakshminarayana, Suresh B., Chen, Yen-Liang, Patra, Debjani, Ornelas, Elizabeth, Koh, Hazel X. Y., Williams, Sarah, Supek, Frantisek, Paape, Daniel, McCulloch, Richard, Kaiser, Marcel, Barrett, Michael P., Jiricek, Jan, Diagana, Thierry T., Mottram, Jeremy C., Rao, Srinivasa P.S.
Publicado 2020