Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Count...

por Oroujeni, Maryam, Abouzayed, Ayman, Lundmark, Fanny, Mitran, Bogdan, Orlova, Anna, Tolmachev, Vladimir, Rosenström, Ulrika
Publicado 2019

Drug Conjugates Based on a Monovalent Affibody Targeting Vector Can Efficiently Eradicate HER2 Positive Human Tumors in an Experimental Mouse Model

por Xu, Tianqi, Ding, Haozhong, Vorobyeva, Anzhelika, Oroujeni, Maryam, Orlova, Anna, Tolmachev, Vladimir, Gräslund, Torbjörn
Publicado 2020

Preclinical Evaluation of [(68)Ga]Ga-DFO-ZEGFR:2377: A Promising Affibody-Based Probe for Noninvasive PET Imaging of EGFR Expression in Tumors

por Oroujeni, Maryam, Garousi, Javad, Andersson, Ken G., Löfblom, John, Mitran, Bogdan, Orlova, Anna, Tolmachev, Vladimir
Publicado 2018

(177)Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry

por Abouzayed, Ayman, Seitova, Kamila, Lundmark, Fanny, Bodenko, Vitalina, Oroujeni, Maryam, Tolmachev, Vladimir, Rosenström, Ulrika, Orlova, Anna
Publicado 2023

Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein

por Vorobyeva, Anzhelika, Oroujeni, Maryam, Lindbo, Sarah, Hober, Sophia, Xu, Tianqi, Liu, Yongsheng, Rinne, Sara S., Garousi, Javad
Publicado 2020

Affibody-Derived Drug Conjugates Targeting HER2: Effect of Drug Load on Cytotoxicity and Biodistribution

por Ding, Haozhong, Xu, Tianqi, Zhang, Jie, Tolmachev, Vladimir, Oroujeni, Maryam, Orlova, Anna, Gräslund, Torbjörn, Vorobyeva, Anzhelika
Publicado 2021

Feasibility of imaging of epidermal growth factor receptor expression with ZEGFR:2377 affibody molecule labeled with (99m)Tc using a peptide-based cysteine-containing chelator

por Andersson, Ken G., Oroujeni, Maryam, Garousi, Javad, Mitran, Bogdan, Ståhl, Stefan, Orlova, Anna, Löfblom, John, Tolmachev, Vladimir
Publicado 2016

Preclinical Evaluation of a New Format of (68)Ga- and (111)In-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and...

por Liu, Yongsheng, Yu, Shengze, Xu, Tianqi, Bodenko, Vitalina, Orlova, Anna, Oroujeni, Maryam, Rinne, Sara S., Tolmachev, Vladimir, Vorobyeva, Anzhelika, Gräslund, Torbjörn
Publicado 2022

Cyclic versus Noncyclic Chelating Scaffold for (89)Zr-Labeled ZEGFR:2377 Affibody Bioconjugates Targeting Epidermal Growth Factor Receptor Overexpression

por Summer, Dominik, Garousi, Javad, Oroujeni, Maryam, Mitran, Bogdan, Andersson, Ken G., Vorobyeva, Anzhelika, Löfblom, John, Orlova, Anna, Tolmachev, Vladimir, Decristoforo, Clemens
Publicado 2017

Influence of composition of cysteine-containing peptide-based chelators on biodistribution of (99m)Tc-labeled anti-EGFR affibody molecules

por Oroujeni, Maryam, Andersson, Ken G., Steinhardt, Xenia, Altai, Mohamed, Orlova, Anna, Mitran, Bogdan, Vorobyeva, Anzhelika, Garousi, Javad, Tolmachev, Vladimir, Löfblom, John
Publicado 2018

Comparative Evaluation of Novel (177)Lu-Labeled PNA Probes for Affibody-Mediated PNA-Based Pretargeting

por Tano, Hanna, Oroujeni, Maryam, Vorobyeva, Anzhelika, Westerlund, Kristina, Liu, Yongsheng, Xu, Tianqi, Vasconcelos, Daniel, Orlova, Anna, Karlström, Amelie Eriksson, Tolmachev, Vladimir
Publicado 2021

The Use of a Non-Conventional Long-Lived Gallium Radioisotope (66)Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR:2377 Affibody Molecule

por Oroujeni, Maryam, Xu, Tianqi, Gagnon, Katherine, Rinne, Sara S., Weis, Jan, Garousi, Javad, Andersson, Ken G., Löfblom, John, Orlova, Anna, Tolmachev, Vladimir
Publicado 2021

Preclinical Evaluation of (99m)Tc-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake

por Oroujeni, Maryam, Rinne, Sara S., Vorobyeva, Anzhelika, Loftenius, Annika, Feldwisch, Joachim, Jonasson, Per, Chernov, Vladimir, Orlova, Anna, Frejd, Fredrik Y., Tolmachev, Vladimir
Publicado 2021

Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein

por Garousi, Javad, Ding, Haozhong, von Witting, Emma, Xu, Tianqi, Vorobyeva, Anzhelika, Oroujeni, Maryam, Orlova, Anna, Hober, Sophia, Gräslund, Torbjörn, Tolmachev, Vladimir
Publicado 2021

Effect of Inter-Domain Linker Composition on Biodistribution of ABD-Fused Affibody-Drug Conjugates Targeting HER2

por Xu, Tianqi, Zhang, Jie, Oroujeni, Maryam, Tretyakova, Maria S., Bodenko, Vitalina, Belousov, Mikhail V., Orlova, Anna, Tolmachev, Vladimir, Vorobyeva, Anzhelika, Gräslund, Torbjörn
Publicado 2022

Direct In Vivo Comparison of (99m)Tc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy

por Tolmachev, Vladimir, Bodenko, Vitalina, Oroujeni, Maryam, Deyev, Sergey, Konovalova, Elena, Schulga, Alexey, Lindbo, Sarah, Hober, Sophia, Bragina, Olga, Orlova, Anna, Vorobyeva, Anzhelika
Publicado 2022

The Influence of Domain Permutations of an Albumin-Binding Domain-Fused HER2-Targeting Affibody-Based Drug Conjugate on Tumor Cell Proliferation and Therapy Efficacy

por Yin, Wen, Xu, Tianqi, Altai, Mohamed, Oroujeni, Maryam, Zhang, Jie, Vorobyeva, Anzhelika, Vorontsova, Olga, Vtorushin, Sergey V., Tolmachev, Vladimir, Gräslund, Torbjörn, Orlova, Anna
Publicado 2021

Evaluation of an Affibody-Based Binder for Imaging of Immune Check-Point Molecule B7-H3

por Oroujeni, Maryam, Bezverkhniaia, Ekaterina A., Xu, Tianqi, Liu, Yongsheng, Plotnikov, Evgenii V., Karlberg, Ida, Ryer, Eva, Orlova, Anna, Tolmachev, Vladimir, Frejd, Fredrik Y.
Publicado 2022

Phase I clinical evaluation of (99m)Tc-labeled Affibody molecule for imaging HER2 expression in breast cancer

por Bragina, Olga, Chernov, Vladimir, Larkina, Mariia, Rybina, Anstasiya, Zelchan, Roman, Garbukov, Eugeniy, Oroujeni, Maryam, Loftenius, Annika, Orlova, Anna, Sörensen, Jens, Frejd, Fredrik Y., Tolmachev, Vladimir
Publicado 2023