Adjuvant inhibition of iAPC function in the tumor microenvironment promotes therapeutic immunity in the setting of vaccination-induced T cell anti-tumor response

por Antonios, Joseph, Soto, Horacio, Orpilla, Joey, Shin, Namjo, Everson, Richard, Liau, Linda, Prins, Robert
Publicado 2015

Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma

por Lee, Alexander H., Sun, Lu, Mochizuki, Aaron Y., Reynoso, Jeremy G., Orpilla, Joey, Chow, Frances, Kienzler, Jenny C., Everson, Richard G., Nathanson, David A., Bensinger, Steven J., Liau, Linda M., Cloughesy, Timothy, Hugo, Willy, Prins, Robert M.
Publicado 2021

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

por Cloughesy, Timothy F., Mochizuki, Aaron Y., Orpilla, Joey R., Hugo, Willy, Lee, Alexander H., Davidson, Tom B., Wang, Anthony C., Ellingson, Benjamin M., Rytlewski, Julie A., Sanders, Catherine M., Kawaguchi, Eric S., Du, Lin, Li, Gang, Yong, William H., Gaffey, Sarah C., Cohen, Adam L., Mellinghoff, Ingo K., Lee, Eudocia Q., Reardon, David A., O’Brien, Barbara J., Butowski, Nicholas A., Nghiemphu, Phioanh L., Clarke, Jennifer L., Arrillaga-Romany, Isabel C., Colman, Howard, Kaley, Thomas J., de Groot, John F., Liau, Linda M., Wen, Patrick Y., Prins, Robert M.
Publicado 2019