Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production

por Bennett, Neal K., Lee, Megan, Orr, Adam L., Nakamura, Ken
Publicado 2023

Adenosine A(2A) receptor mediates microglial process retraction

por Orr, Anna G, Orr, Adam L, Li, Xiao-Jiang, Gross, Robert E, Traynelis, Stephen F
Publicado 2009

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates()

por Quinlan, Casey L., Perevoshchikova, Irina V., Hey-Mogensen, Martin, Orr, Adam L., Brand, Martin D.
Publicado 2013

The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production

por Goncalves, Renata L.S., Watson, Mark A., Wong, Hoi-Shan, Orr, Adam L., Brand, Martin D.
Publicado 2019

Novel Inhibitors of Mitochondrial sn-Glycerol 3-phosphate Dehydrogenase

por Orr, Adam L., Ashok, Deepthi, Sarantos, Melissa R., Ng, Ryan, Shi, Tong, Gerencser, Akos A., Hughes, Robert E., Brand, Martin D.
Publicado 2014

Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function

por Orr, Adam L., Kim, Chaeyoung, Jimenez-Morales, David, Newton, Billy W., Johnson, Jeffrey R., Krogan, Nevan J., Swaney, Danielle L., Mahley, Robert W.
Publicado 2019

Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons

por Pathak, Divya, Berthet, Amandine, Bendor, Jacob T., Yu, Katharine, Sellnow, Rhyomi C., Orr, Adam L., Nguyen, Mai K, Edwards, Robert H., Manfredsson, Fredric P., Nakamura, Ken
Publicado 2017

Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling

por Pranski, Elaine L, Dalal, Nirjari V, Herskowitz, Jeremy H, Orr, Adam L, Roesch, Leah A, Fritz, Jason J, Heilman, Craig, Lah, James J, Levey, Allan I, Betarbet, Ranjita S
Publicado 2012

Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

por Licht-Murava, Avital, Meadows, Samantha M., Palaguachi, Fernando, Song, Soomin C., Jackvony, Stephanie, Bram, Yaron, Zhou, Constance, Schwartz, Robert E., Froemke, Robert C., Orr, Adam L., Orr, Anna G.
Publicado 2023

To be or not to be pink(1): contradictory findings in an animal model for Parkinson’s disease

por de Haas, Ria, Heltzel, Lisa C M W, Tax, Denise, van den Broek, Petra, Steenbreker, Hilbert, Verheij, Michel M M, Russel, Frans G M, Orr, Adam L, Nakamura, Ken, Smeitink, Jan A M
Publicado 2019

Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP

por Cakir, Zeynep, Lord, Samuel J., Zhou, Yuan, Jang, Gwendolyn M., Polacco, Benjamin J., Eckhardt, Manon, Jimenez-Morales, David, Newton, Billy W., Orr, Adam L., Johnson, Jeffrey R., da Cruz, Alexandre, Mullins, R. Dyche, Krogan, Nevan J., Mahley, Robert W., Swaney, Danielle L.
Publicado 2023

Suppressors of superoxide production from mitochondrial complex III

por Orr, Adam L., Vargas, Leonardo, Turk, Carolina N., Baaten, Janine E., Matzen, Jason T., Dardov, Victoria J., Attle, Stephen J., Li, Jing, Quackenbush, Douglas C., Goncalves, Renata L. S., Perevoshchikova, Irina V., Petrassi, H. Michael, Meeusen, Shelly L., Ainscow, Edward K., Brand, Martin D.
Publicado 2015