Genetic Determinants of Breast Cancer Risk in Childhood Cancer Survivors

por Meier, Magda, Orr, Nick
Publicado 2017

The topology of data: opportunities for cancer research

por Loughrey, Ciara F, Fitzpatrick, Padraig, Orr, Nick, Jurek-Loughrey, Anna
Publicado 2021

Neovascular Age-Related Macular Degeneration Risk Based on CFH, LOC387715/HTRA1, and Smoking

por Hughes, Anne E, Orr, Nick, Patterson, Chris, Esfandiary, Hossein, Hogg, Ruth, McConnell, Vivienne, Silvestri, Giuliana, Chakravarthy, Usha
Publicado 2007

A Genome Scan for Positive Selection in Thoroughbred Horses

por Gu, Jingjing, Orr, Nick, Park, Stephen D., Katz, Lisa M., Sulimova, Galina, MacHugh, David E., Hill, Emmeline W.
Publicado 2009

The SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression

por Naeli, Parisa, Zhang, Xu, Snell, Patric Harris, Chatterjee, Susanta, Kamran, Muhammad, Ladak, Reese Jalal, Orr, Nick, Duchaine, Thomas, Sonenberg, Nahum, Jafarnejad, Seyed Mehdi
Publicado 2023

Genetic Variants at Chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 Influence the Risk of Breast Cancer in Men

por Orr, Nick, Cooke, Rosie, Jones, Michael, Fletcher, Olivia, Dudbridge, Frank, Chilcott-Burns, Sarah, Tomczyk, Katarzyna, Broderick, Peter, Houlston, Richard, Ashworth, Alan, Swerdlow, Anthony
Publicado 2011

A Sequence Polymorphism in MSTN Predicts Sprinting Ability and Racing Stamina in Thoroughbred Horses

por Hill, Emmeline W., Gu, Jingjing, Eivers, Suzanne S., Fonseca, Rita G., McGivney, Beatrice A., Govindarajan, Preethi, Orr, Nick, Katz, Lisa M., MacHugh, David
Publicado 2010

Correction: A Sequence Polymorphism in MSTN Predicts Sprinting Ability and Racing Stamina in Thoroughbred Horses

por Hill, Emmeline W., Gu, Jingjing, Eivers, Suzanne S., Fonseca, Rita G., McGivney, Beatrice A., Govindarajan, Preethi, Orr, Nick, Katz, Lisa M., MacHugh, David E.
Publicado 2010

Population-based estimates of the prevalence of FMR1 expansion mutations in women with early menopause and primary ovarian insufficiency

por Murray, Anna, Schoemaker, Minouk J., Bennett, Claire E., Ennis, Sarah, Macpherson, James N., Jones, Michael, Morris, Danielle H., Orr, Nick, Ashworth, Alan, Jacobs, Patricia A., Swerdlow, Anthony J.
Publicado 2014

Capture Hi-C identifies putative target genes at 33 breast cancer risk loci

por Baxter, Joseph S., Leavy, Olivia C., Dryden, Nicola H., Maguire, Sarah, Johnson, Nichola, Fedele, Vita, Simigdala, Nikiana, Martin, Lesley-Ann, Andrews, Simon, Wingett, Steven W., Assiotis, Ioannis, Fenwick, Kerry, Chauhan, Ritika, Rust, Alistair G., Orr, Nick, Dudbridge, Frank, Haider, Syed, Fletcher, Olivia
Publicado 2018

Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer

por Loveday, Chey, Litchfield, Kevin, Levy, Max, Holroyd, Amy, Broderick, Peter, Kote-Jarai, Zsofia, Dunning, Alison M, Muir, Kenneth, Peto, Julian, Eeles, Rosalind, Easton, Douglas F, Dudakia, Darshna, Orr, Nick, Pashayan, Nora, Reid, Alison, Huddart, Robert A, Houlston, Richard S, Turnbull, Clare
Publicado 2017

Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C

por Dryden, Nicola H., Broome, Laura R., Dudbridge, Frank, Johnson, Nichola, Orr, Nick, Schoenfelder, Stefan, Nagano, Takashi, Andrews, Simon, Wingett, Steven, Kozarewa, Iwanka, Assiotis, Ioannis, Fenwick, Kerry, Maguire, Sarah L., Campbell, James, Natrajan, Rachael, Lambros, Maryou, Perrakis, Eleni, Ashworth, Alan, Fraser, Peter, Fletcher, Olivia
Publicado 2014

Comprehensive resequence analysis of a 136 kb region of human chromosome 8q24 associated with prostate and colon cancers

por Yeager, Meredith, Xiao, Nianqing, Hayes, Richard B., Bouffard, Pascal, Desany, Brian, Burdett, Laura, Orr, Nick, Matthews, Casey, Qi, Liqun, Crenshaw, Andrew, Markovic, Zdenek, Fredrikson, Karin M., Jacobs, Kevin B., Amundadottir, Laufey, Jarvie, Thomas P., Hunter, David J., Hoover, Robert, Thomas, Gilles, Harkins, Timothy T., Chanock, Stephen J.
Publicado 2008

Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk

por Johansson, Annelie, Palli, Domenico, Masala, Giovanna, Grioni, Sara, Agnoli, Claudia, Tumino, Rosario, Giurdanella, Maria Concetta, Fasanelli, Francesca, Sacerdote, Carlotta, Panico, Salvatore, Mattiello, Amalia, Polidoro, Silvia, Jones, Michael E., Schoemaker, Minouk J., Orr, Nick, Tomczyk, Katarzyna, Johnson, Nichola, Fletcher, Olivia, Perduca, Vittorio, Baglietto, Laura, Dugué, Pierre-Antoine, Southey, Melissa C., Giles, Graham G., English, Dallas R., Milne, Roger L., Severi, Gianluca, Ambatipudi, Srikant, Cuenin, Cyrille, Chajès, Veronique, Romieu, Isabelle, Herceg, Zdenko, Swerdlow, Anthony J., Vineis, Paolo, Flanagan, James M.
Publicado 2019

Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

por Sud, Amit, Thomsen, Hauke, Law, Philip J., Försti, Asta, Filho, Miguel Inacio da Silva, Holroyd, Amy, Broderick, Peter, Orlando, Giulia, Lenive, Oleg, Wright, Lauren, Cooke, Rosie, Easton, Douglas, Pharoah, Paul, Dunning, Alison, Peto, Julian, Canzian, Federico, Eeles, Rosalind, Kote-Jarai, ZSofia, Muir, Kenneth, Pashayan, Nora, Hoffmann, Per, Nöthen, Markus M., Jöckel, Karl-Heinz, Strandmann, Elke Pogge von, Lightfoot, Tracy, Kane, Eleanor, Roman, Eve, Lake, Annette, Montgomery, Dorothy, Jarrett, Ruth F., Swerdlow, Anthony J., Engert, Andreas, Orr, Nick, Hemminki, Kari, Houlston, Richard S.
Publicado 2017

Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

por Sud, Amit, Thomsen, Hauke, Law, Philip J., Försti, Asta, da Silva Filho, Miguel Inacio, Holroyd, Amy, Broderick, Peter, Orlando, Giulia, Lenive, Oleg, Wright, Lauren, Cooke, Rosie, Easton, Douglas, Pharoah, Paul, Dunning, Alison, Peto, Julian, Canzian, Federico, Eeles, Rosalind, Kote-Jarai, Zsofia, Muir, Kenneth, Pashayan, Nora, Hoffmann, Per, Nöthen, Markus M., Jöckel, Karl-Heinz, von Strandmann, Elke Pogge, Lightfoot, Tracy, Kane, Eleanor, Roman, Eve, Lake, Annette, Montgomery, Dorothy, Jarrett, Ruth F., Swerdlow, Anthony J., Engert, Andreas, Orr, Nick, Hemminki, Kari, Houlston, Richard S.
Publicado 2019

Common Susceptibility Loci for Male Breast Cancer

por Maguire, Sarah, Perraki, Eleni, Tomczyk, Katarzyna, Jones, Michael E, Fletcher, Olivia, Pugh, Matthew, Winter, Timothy, Thompson, Kyle, Cooke, Rosie, Trainer, Alison, James, Paul, Bojesen, Stig, Flyger, Henrik, Nevanlinna, Heli, Mattson, Johanna, Friedman, Eitan, Laitman, Yael, Palli, Domenico, Masala, Giovanna, Zanna, Ines, Ottini, Laura, Silvestri, Valentina, Hollestelle, Antoinette, Hooning, Maartje J, Novaković, Srdjan, Krajc, Mateja, Gago-Dominguez, Manuela, Castelao, Jose Esteban, Olsson, Hakan, Hedenfalk, Ingrid, Saloustros, Emmanouil, Georgoulias, Vasilios, Easton, Douglas F, Pharoah, Paul, Dunning, Alison M, Bishop, D Timothy, Neuhausen, Susan L, Steele, Linda, Ashworth, Alan, Garcia Closas, Montserrat, Houlston, Richard, Swerdlow, Anthony, Orr, Nick
Publicado 2020

Genome-wide association study identifies a novel variant in RAD51B associated with male breast cancer risk

por Orr, Nick, Lemnrau, Alina, Cooke, Rosie, Fletcher, Olivia, Tomczyk, Katarzyna, Jones, Michael, Johnson, Nichola, Lord, Christopher J, Mitsopoulos, Costas, Zvelebil, Marketa, McDade, Simon S, Buck, Gemma, Blancher, Christine, Consortium, KConFab, Trainer, Alison H, James, Paul A, Bojesen, Stig E, Bokmand, Susanne, Nevanlinna, Heli, Mattson, Johanna, Friedman, Eitan, Laitman, Yael, Palli, Domenico, Masala, Giovanna, Zanna, Ines, Ottini, Laura, Giannini, Giuseppe, Hollestelle, Antoinette, van den Ouweland, Ans M.W., Novaković, Srdjan, Krajc, Mateja, Gago-Dominguez, Manuela, Castelao, Jose Esteban, Olsson, Håkan, Hedenfalk, Ingrid, Easton, Douglas F, Pharoah, Paul DP, Dunning, Alison M, Bishop, D Timothy, Neuhausen, Susan L, Steele, Linda, Houlston, Richard S, Garcia-Closas, Montserrat, Ashworth, Alan, Swerdlow, Anthony J
Publicado 2012

High‐throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium

por Abubakar, Mustapha, Howat, William J, Daley, Frances, Zabaglo, Lila, McDuffus, Leigh‐Anne, Blows, Fiona, Coulson, Penny, Raza Ali, H, Benitez, Javier, Milne, Roger, Brenner, Herman, Stegmaier, Christa, Mannermaa, Arto, Chang‐Claude, Jenny, Rudolph, Anja, Sinn, Peter, Couch, Fergus J, Tollenaar, Rob A.E.M., Devilee, Peter, Figueroa, Jonine, Sherman, Mark E, Lissowska, Jolanta, Hewitt, Stephen, Eccles, Diana, Hooning, Maartje J, Hollestelle, Antoinette, WM Martens, John, HM van Deurzen, Carolien, Investigators, kConFab, Bolla, Manjeet K, Wang, Qin, Jones, Michael, Schoemaker, Minouk, Broeks, Annegien, van Leeuwen, Flora E, Van't Veer, Laura, Swerdlow, Anthony J, Orr, Nick, Dowsett, Mitch, Easton, Douglas, Schmidt, Marjanka K, Pharoah, Paul D, Garcia‐Closas, Montserrat
Publicado 2016

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

por Abubakar, Mustapha, Orr, Nick, Daley, Frances, Coulson, Penny, Ali, H. Raza, Blows, Fiona, Benitez, Javier, Milne, Roger, Brenner, Herman, Stegmaier, Christa, Mannermaa, Arto, Chang-Claude, Jenny, Rudolph, Anja, Sinn, Peter, Couch, Fergus J., Devilee, Peter, Tollenaar, Rob A. E. M., Seynaeve, Caroline, Figueroa, Jonine, Sherman, Mark E., Lissowska, Jolanta, Hewitt, Stephen, Eccles, Diana, Hooning, Maartje J., Hollestelle, Antoinette, Martens, John W. M., van Deurzen, Carolien H. M., Investigators, kConFab, Bolla, Manjeet K., Wang, Qin, Jones, Michael, Schoemaker, Minouk, Wesseling, Jelle, van Leeuwen, Flora E., Van ‘t Veer, Laura, Easton, Douglas, Swerdlow, Anthony J., Dowsett, Mitch, Pharoah, Paul D., Schmidt, Marjanka K., Garcia-Closas, Montserrat
Publicado 2016