Real-Time Quaking- Induced Conversion Assays for Prion Diseases, Synucleinopathies, and Tauopathies

por Vascellari, Sarah, Orrù, Christina D., Caughey, Byron
Publicado 2022

Rapid and Sensitive RT-QuIC Detection of Human Creutzfeldt-Jakob Disease Using Cerebrospinal Fluid

por Orrú, Christina D., Groveman, Bradley R., Hughson, Andrew G., Zanusso, Gianluigi, Coulthart, Michael B., Caughey, Byron
Publicado 2015

Prion Disease Blood Test Using Immunoprecipitation and Improved Quaking-Induced Conversion

por Orrú, Christina D., Wilham, Jason M., Raymond, Lynne D., Kuhn, Franziska, Schroeder, Björn, Raeber, Alex J., Caughey, Byron
Publicado 2011

Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids

por Groveman, Bradley R., Foliaki, Simote T., Orru, Christina D., Zanusso, Gianluigi, Carroll, James A., Race, Brent, Haigh, Cathryn L.
Publicado 2019

Creutzfeldt–Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues

por Luk, Collin C., Mathiason, Candace K., Orrù, Christina D., Jansen, Gerard H., Thiele, Allison, Caughey, Byron, Sim, Valerie L.
Publicado 2021

Factors That Improve RT-QuIC Detection of Prion Seeding Activity

por Orrú, Christina D., Hughson, Andrew G., Groveman, Bradley R., Campbell, Katrina J., Anson, Kelsie J., Manca, Matteo, Kraus, Allison, Caughey, Byron
Publicado 2016

Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains

por Orrú, Christina D., Groveman, Bradley R., Raymond, Lynne D., Hughson, Andrew G., Nonno, Romolo, Zou, Wenquan, Ghetti, Bernardino, Gambetti, Pierluigi, Caughey, Byron
Publicado 2015

Correction: Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains

por Orrú, Christina D., Groveman, Bradley R., Raymond, Lynne D., Hughson, Andrew G., Nonno, Romolo, Zou, Wenquan, Ghetti, Bernardino, Gambetti, Pierluigi, Caughey, Byron
Publicado 2015

Prion Seeding Activities of Mouse Scrapie Strains with Divergent PrP(Sc) Protease Sensitivities and Amyloid Plaque Content Using RT-QuIC and eQuIC

por Vascellari, Sarah, Orrù, Christina D., Hughson, Andrew G., King, Declan, Barron, Rona, Wilham, Jason M., Baron, Gerald S., Race, Brent, Pani, Alessandra, Caughey, Byron
Publicado 2012

Extended and direct evaluation of RT‐QuIC assays for Creutzfeldt‐Jakob disease diagnosis

por Groveman, Bradley R., Orrú, Christina D., Hughson, Andrew G., Bongianni, Matilde, Fiorini, Michele, Imperiale, Daniele, Ladogana, Anna, Pocchiari, Maurizio, Zanusso, Gianluigi, Caughey, Byron
Publicado 2016

Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction

por Foliaki, Simote T., Smith, Anna, Schwarz, Benjamin, Bohrnsen, Eric, Bosio, Catharine M., Williams, Katie, Orrú, Christina D., Lachenauer, Hailey, Groveman, Bradley R., Haigh, Cathryn L.
Publicado 2023

Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

por Groveman, Bradley R., Orrù, Christina D., Hughson, Andrew G., Raymond, Lynne D., Zanusso, Gianluigi, Ghetti, Bernardino, Campbell, Katrina J., Safar, Jiri, Galasko, Douglas, Caughey, Byron
Publicado 2018

Correction to: Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

por Groveman, Bradley R., Orrù, Christina D., Hughson, Andrew G., Raymond, Lynne D., Zanusso, Gianluigi, Ghetti, Bernardino, Campbell, Katrina J., Safar, Jiri, Galasko, Douglas, Caughey, Byron
Publicado 2020

Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays

por Wilham, Jason M., Orrú, Christina D., Bessen, Richard A., Atarashi, Ryuichiro, Sano, Kazunori, Race, Brent, Meade-White, Kimberly D., Taubner, Lara M., Timmes, Andrew, Caughey, Byron
Publicado 2010

Role of the central lysine cluster and scrapie templating in the transmissibility of synthetic prion protein aggregates

por Groveman, Bradley R., Raymond, Gregory J., Campbell, Katrina J., Race, Brent, Raymond, Lynne D., Hughson, Andrew G., Orrú, Christina D., Kraus, Allison, Phillips, Katie, Caughey, Byron
Publicado 2017

Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease

por Hall, Sara, Orrù, Christina D., Serrano, Geidy E., Galasko, Douglas, Hughson, Andrew G., Groveman, Bradley R., Adler, Charles H., Beach, Thomas G., Caughey, Byron, Hansson, Oskar
Publicado 2022

A rapid α‐synuclein seed assay of Parkinson’s disease CSF panel shows high diagnostic accuracy

por Orrù, Christina D., Ma, Thong C., Hughson, Andrew G., Groveman, Bradley R., Srivastava, Ankit, Galasko, Douglas, Angers, Rachel, Downey, Patrick, Crawford, Karen, Hutten, Samantha J., Kang, Un Jung, Caughey, Byron
Publicado 2020

Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies

por Rossi, Marcello, Candelise, Niccolò, Baiardi, Simone, Capellari, Sabina, Giannini, Giulia, Orrù, Christina D., Antelmi, Elena, Mammana, Angela, Hughson, Andrew G., Calandra-Buonaura, Giovanna, Ladogana, Anna, Plazzi, Giuseppe, Cortelli, Pietro, Caughey, Byron, Parchi, Piero
Publicado 2020

Transmission of CJD from nasal brushings but not spinal fluid or RT‐QuIC product

por Raymond, Gregory J., Race, Brent, Orrú, Christina D., Raymond, Lynne D., Bongianni, Matilde, Fiorini, Michele, Groveman, Bradley R., Ferrari, Sergio, Sacchetto, Luca, Hughson, Andrew G., Monaco, Salvatore, Pocchiari, Maurizio, Zanusso, Gianluigi, Caughey, Byron
Publicado 2020

Correction to: Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies

por Rossi, Marcello, Candelise, Niccolò, Baiardi, Simone, Capellari, Sabina, Giannini, Giulia, Orrù, Christina D., Antelmi, Elena, Mammana, Angela, Hughson, Andrew G., Calandra-Buonaura, Giovanna, Ladogana, Anna, Plazzi, Giuseppe, Cortelli, Pietro, Caughey, Byron, Parchi, Piero
Publicado 2020