Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics

por Orris, Benjamin, Huynh, Kevin W, Ammirati, Mark, Han, Seungil, Bolaños, Ben, Carmody, Jason, Petroski, Matthew D, Bosbach, Benedikt, Shields, David J, Stivers, James T
Publicado 2022

Guanine-containing ssDNA and RNA induce dimeric and tetrameric SAMHD1 in cryo-EM and binding studies

por Orris, Benjamin, Sung, Min Woo, Bhat, Shridhar, Xu, Yingrong, Huynh, Kevin W., Han, Seungil, Johnson, Darren C., Bosbach, Benedikt, Shields, David J., Stivers, James T.
Publicado 2023