Metabolomic, proteomic and single cell proteomic analysis of cancer cells treated with the KRAS(G12D) inhibitor MRTX1133

por Orsburn, Benjamin C.
Publicado 2023

Acetic acid is a superior acidifier for sub-nanogram and single cell proteomic studies

por Orsburn, Benjamin C.
Publicado 2023

Time-of-Flight Fragmentation Spectra Generated by the Proteomic Analysis of Single Human Cells Do Not Exhibit Atypical Fragmentation Patterns

por Orsburn, Benjamin C.
Publicado 2023

An integrated method for single cell proteomics with simultaneous measurements of intracellular drug concentration implicates new mechanisms for adaptation to KRAS(G12D) inhibitors

por Orsburn, Benjamin C.
Publicado 2023

Metabolomic, Proteomic, and Single-Cell Proteomic Analysis of Cancer Cells Treated with the KRAS(G12D) Inhibitor MRTX1133

por Orsburn, Benjamin C.
Publicado 2023

Proteome Discoverer—A Community Enhanced Data Processing Suite for Protein Informatics

por Orsburn, Benjamin C.
Publicado 2021

Evaluation of the Sensitivity of Proteomics Methods Using the Absolute Copy Number of Proteins in a Single Cell as a Metric

por Orsburn, Benjamin C.
Publicado 2021

The Cannabis Proteome Draft Map Project

por Jenkins, Conor, Orsburn, Benjamin
Publicado 2020

SCP Viz – A universal graphical user interface for single protein analysis in single cell proteomics datasets

por Warshanna, Ahmed, Orsburn, Benjamin C.
Publicado 2023

Cloud Computing Based Immunopeptidomics Utilizing Community Curated Variant Libraries Simplifies and Improves Neo-Antigen Discovery in Metastatic Melanoma

por Prakash, Amol, Mahoney, Keira E., Orsburn, Benjamin C.
Publicado 2021

Insights into protein post-translational modification landscapes of individual human cells by trapped ion mobility time-of-flight mass spectrometry

por Orsburn, Benjamin C., Yuan, Yuting, Bumpus, Namandjé N.
Publicado 2022

Biotransformation of Efavirenz and Proteomic Analysis of Cytochrome P450s and UDP-Glucuronosyltransferases in Mouse, Macaque, and Human Brain-Derived In Vitro Systems

por Wheeler, Abigail M., Orsburn, Benjamin C., Bumpus, Namandjé N.
Publicado 2023

Standard Flow Multiplexed Proteomics (SFloMPro)—An Accessible Alternative to NanoFlow Based Shotgun Proteomics

por Orsburn, Benjamin C., Miller, Sierra D., Jenkins, Conor J.
Publicado 2022

Tenofovir Activation is Diminished in the Brain and Liver of Creatine Kinase Brain-Type Knockout Mice

por Eberhard, Colten D., Mosher, Eric P., Bumpus, Namandjé N., Orsburn, Benjamin C.
Publicado 2023

The SAGA HAT module is tethered by its SWIRM domain and modulates activity of the SAGA DUB module

por Haile, Sara T., Rahman, Sanim, Fields, James K., Orsburn, Benjamin C., Bumpus, Namandjé N., Wolberger, Cynthia
Publicado 2023

Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies

por Wheeler, Abigail M., Eberhard, Colten D., Mosher, Eric P., Yuan, Yuting, Wilkins, Hannah N., Seneviratne, Herana Kamal, Orsburn, Benjamin C., Bumpus, Namandjé N.
Publicado 2023

Characterization of a novel AraC/XylS-regulated family of N-acyltransferases in pathogens of the order Enterobacterales

por Belmont-Monroy, Laura, Saitz-Rojas, Waleska, Soria-Bustos, Jorge, Mickey, Abigail S., Sherman, Nicholas E., Orsburn, Benjamin C., Ruiz-Perez, Fernando, Santiago, Araceli E.
Publicado 2020

Cocaine Regulates Antiretroviral Therapy CNS Access Through Pregnane-X Receptor-Mediated Drug Transporter and Metabolizing Enzyme Modulation at the Blood Brain Barrier

por Fridman, Lisa B., Knerler, Stephen, Price, Amira-Storm, Ortiz, Rodnie Colón, Mercado, Alicia, Wilkins, Hannah, Flores, Bianca R., Orsburn, Benjamin C., Williams, Dionna W.
Publicado 2023

Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer’s disease

por Gonzalez-Gil, Anabel, Porell, Ryan N., Fernandes, Steve M., Maenpaa, Eila, Li, T. August, Li, Tong, Wong, Philip C., Aoki, Kazuhiro, Tiemeyer, Michael, Yu, Zaikuan J., Orsburn, Benjamin C., Bumpus, Namandjé N., Matthews, Russell T., Schnaar, Ronald L.
Publicado 2022

Chorioamnionitis disrupts erythropoietin and melatonin homeostasis through the placental-fetal-brain axis during critical developmental periods

por Kitase, Yuma, Madurai, Nethra K., Hamimi, Sarah, Hellinger, Ryan L., Odukoya, O. Angel, Ramachandra, Sindhu, Muthukumar, Sankar, Vasan, Vikram, Sevensky, Riley, Kirk, Shannon E., Gall, Alexander, Heck, Timothy, Ozen, Maide, Orsburn, Benjamin C., Robinson, Shenandoah, Jantzie, Lauren L.
Publicado 2023