Absence of SARM1 Rescues Development and Survival of NMNAT2-Deficient Axons

por Gilley, Jonathan, Orsomando, Giuseppe, Nascimento-Ferreira, Isabel, Coleman, Michael P.
Publicado 2015

Crystal structure of human nicotinic acid phosphoribosyltransferase

por Marletta, Ada Serena, Massarotti, Alberto, Orsomando, Giuseppe, Magni, Giulio, Rizzi, Menico, Garavaglia, Silvia
Publicado 2015

Genomics-Guided Analysis of NAD Recycling Yields Functional Elucidation of COG1058 as a New Family of Pyrophosphatases

por Cialabrini, Lucia, Ruggieri, Silverio, Kazanov, Marat D., Sorci, Leonardo, Mazzola, Francesca, Orsomando, Giuseppe, Osterman, Andrei L., Raffaelli, Nadia
Publicado 2013

Simultaneous Single-Sample Determination of NMNAT Isozyme Activities in Mouse Tissues

por Orsomando, Giuseppe, Cialabrini, Lucia, Amici, Adolfo, Mazzola, Francesca, Ruggieri, Silverio, Conforti, Laura, Janeckova, Lucie, Coleman, Michael P., Magni, Giulio
Publicado 2012

Metabolic Profiling of Alternative NAD Biosynthetic Routes in Mouse Tissues

por Mori, Valerio, Amici, Adolfo, Mazzola, Francesca, Di Stefano, Michele, Conforti, Laura, Magni, Giulio, Ruggieri, Silverio, Raffaelli, Nadia, Orsomando, Giuseppe
Publicado 2014

SARM1 is a multi-functional NAD(P)ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites

por Angeletti, Carlo, Amici, Adolfo, Gilley, Jonathan, Loreto, Andrea, Trapanotto, Antonio G., Antoniou, Christina, Merlini, Elisa, Coleman, Michael P., Orsomando, Giuseppe
Publicado 2022

Biological Activities of the Essential Oil from Erigeron floribundus

por Petrelli, Riccardo, Orsomando, Giuseppe, Sorci, Leonardo, Maggi, Filippo, Ranjbarian, Farahnaz, Biapa Nya, Prosper C., Petrelli, Dezemona, Vitali, Luca A., Lupidi, Giulio, Quassinti, Luana, Bramucci, Massimo, Hofer, Anders, Cappellacci, Loredana
Publicado 2016

Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration

por Loreto, Andrea, Hill, Ciaran S., Hewitt, Victoria L., Orsomando, Giuseppe, Angeletti, Carlo, Gilley, Jonathan, Lucci, Cristiano, Sanchez-Martinez, Alvaro, Whitworth, Alexander J., Conforti, Laura, Dajas-Bailador, Federico, Colemana, Michael P.
Publicado 2020

The NAD(+) precursor NMN activates dSarm to trigger axon degeneration in Drosophila

por Llobet Rosell, Arnau, Paglione, Maria, Gilley, Jonathan, Kocia, Magdalena, Perillo, Giulia, Gasparrini, Massimiliano, Cialabrini, Lucia, Raffaelli, Nadia, Angeletti, Carlo, Orsomando, Giuseppe, Wu, Pei-Hsuan, Coleman, Michael P, Loreto, Andrea, Neukomm, Lukas Jakob
Publicado 2022

Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1

por Loreto, Andrea, Angeletti, Carlo, Gu, Weixi, Osborne, Andrew, Nieuwenhuis, Bart, Gilley, Jonathan, Merlini, Elisa, Arthur-Farraj, Peter, Amici, Adolfo, Luo, Zhenyao, Hartley-Tassell, Lauren, Ve, Thomas, Desrochers, Laura M, Wang, Qi, Kobe, Bostjan, Orsomando, Giuseppe, Coleman, Michael P
Publicado 2021