Targeting TNFR2 as a Novel Therapeutic Strategy for Alzheimer’s Disease

por Ortí-Casañ, Natalia, Wu, Yingying, Naudé, Petrus J. W., De Deyn, Peter P., Zuhorn, Inge S., Eisel, Ulrich L. M.
Publicado 2019

A TNF receptor 2 agonist ameliorates neuropathology and improves cognition in an Alzheimer’s disease mouse model

por Ortí-Casañ, Natalia, Zuhorn, Inge S., Naudé, Petrus J. W., De Deyn, Peter P., van Schaik, Pauline E. M., Wajant, Harald, Eisel, Ulrich L. M.
Publicado 2022

The TNFR1 antagonist Atrosimab reduces neuronal loss, glial activation and memory deficits in an acute mouse model of neurodegeneration

por Ortí-Casañ, Natalia, Boerema, Ate S., Köpke, Karina, Ebskamp, Amber, Keijser, Jan, Zhang, Yuequ, Chen, Tingting, Dolga, Amalia M., Broersen, Kerensa, Fischer, Roman, Pfizenmaier, Klaus, Kontermann, Roland E., Eisel, Ulrich L. M.
Publicado 2023

Activation of TNF Receptor 2 Improves Synaptic Plasticity and Enhances Amyloid-β Clearance in an Alzheimer’s Disease Mouse Model with Humanized TNF Receptor 2

por Ortí-Casañ, Natalia, Wajant, Harald, Kuiperij, H. Bea, Hooijsma, Annelien, Tromp, Leon, Poortman, Isabelle L., Tadema, Norick, de Lange, Julia H.E., Verbeek, Marcel M., De Deyn, Peter P., Naudé, Petrus J.W., Eisel, Ulrich L.M.
Publicado 2023