SIRT1 Is Necessary for Proficient Telomere Elongation and Genomic Stability of Induced Pluripotent Stem Cells

por De Bonis, Maria Luigia, Ortega, Sagrario, Blasco, Maria A.
Publicado 2014

Suv4-20h Abrogation Enhances Telomere Elongation during Reprogramming and Confers a Higher Tumorigenic Potential to iPS Cells

por Marión, Rosa M., Schotta, Gunnar, Ortega, Sagrario, Blasco, Maria A.
Publicado 2011

Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations

por Varela, Elisa, Muñoz-Lorente, Miguel A., Tejera, Agueda M., Ortega, Sagrario, Blasco, Maria A.
Publicado 2016

The Meiotic Nuclear Lamina Regulates Chromosome Dynamics and Promotes Efficient Homologous Recombination in the Mouse

por Link, Jana, Jahn, Daniel, Schmitt, Johannes, Göb, Eva, Baar, Johannes, Ortega, Sagrario, Benavente, Ricardo, Alsheimer, Manfred
Publicado 2013

A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells

por Olbrich, Teresa, Vega-Sendino, Maria, Murga, Matilde, de Carcer, Guillermo, Malumbres, Marcos, Ortega, Sagrario, Ruiz, Sergio, Fernandez-Capetillo, Oscar
Publicado 2019

Lockdown, Emotional Intelligence, Academic Engagement and Burnout in Pharmacy Students during the Quarantine

por Moreno-Fernandez, Jorge, Ochoa, Julio J., Lopez-Aliaga, Inmaculada, Alferez, Maria Jose M., Gomez-Guzman, Manuel, Lopez-Ortega, Sagrario, Diaz-Castro, Javier
Publicado 2020

ERF deletion rescues RAS deficiency in mouse embryonic stem cells

por Mayor-Ruiz, Cristina, Olbrich, Teresa, Drosten, Matthias, Lecona, Emilio, Vega-Sendino, Maria, Ortega, Sagrario, Dominguez, Orlando, Barbacid, Mariano, Ruiz, Sergio, Fernandez-Capetillo, Oscar
Publicado 2018

A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells

por Ahuja, Akshay K., Jodkowska, Karolina, Teloni, Federico, Bizard, Anna H., Zellweger, Ralph, Herrador, Raquel, Ortega, Sagrario, Hickson, Ian D., Altmeyer, Matthias, Mendez, Juan, Lopes, Massimo
Publicado 2016

A knockin mouse model for human ATP4a(R703C) mutation identified in familial gastric neuroendocrine tumors recapitulates the premalignant condition of the human disease and suggest...

por Calvete, Oriol, Varro, Andrea, Pritchard, D. Mark, Barroso, Alicia, Oteo, Marta, Morcillo, Miguel Ángel, Vargiu, Pierfrancesco, Dodd, Steven, Garcia, Miriam, Reyes, José, Ortega, Sagrario, Benitez, Javier
Publicado 2016

Lymph Node Transplantation Decreases Swelling and Restores Immune Responses in a Transgenic Model of Lymphedema

por Huang, Jung-Ju, Gardenier, Jason C., Hespe, Geoffrey E., García Nores, Gabriela D., Kataru, Raghu P., Ly, Catherine L., Martínez-Corral, Inés, Ortega, Sagrario, Mehrara, Babak J.
Publicado 2016

Decoding protein methylation function with thermal stability analysis

por Sayago, Cristina, Sánchez-Wandelmer, Jana, García, Fernando, Hurtado, Begoña, Lafarga, Vanesa, Prieto, Patricia, Zarzuela, Eduardo, Ximénez-Embún, Pilar, Ortega, Sagrario, Megías, Diego, Fernández-Capetillo, Oscar, Malumbres, Marcos, Munoz, Javier
Publicado 2023

Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging

por Vilas, Jéssica M., Carneiro, Carmen, Da Silva‐Álvarez, Sabela, Ferreirós, Alba, González, Patricia, Gómez, María, Ortega, Sagrario, Serrano, Manuel, García‐Caballero, Tomás, González‐Barcia, Miguel, Vidal, Anxo, Collado, Manuel
Publicado 2018

Conditional deletion of Rcan1 predisposes to hypertension-mediated intramural hematoma and subsequent aneurysm and aortic rupture

por Villahoz, Silvia, Yunes-Leites, Paula Sofía, Méndez-Barbero, Nerea, Urso, Katia, Bonzon-Kulichenko, Elena, Ortega, Sagrario, Nistal, J. Francisco, Vazquez, Jesus, Offermanns, Stefan, Redondo, Juan Miguel, Campanero, Miguel R.
Publicado 2018

Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia–reperfusion injury

por Tan, Can, Norden, Pieter R, Yu, Wei, Liu, Ting, Ujiie, Naoto, Lee, Sun Kyong, Yan, Xiaocai, Dyakiv, Yaryna, Aoto, Kazushi, Ortega, Sagrario, De Plaen, Isabelle G, Sampath, Venkatesh, Kume, Tsutomu
Publicado 2023

Live imaging of neolymphangiogenesis identifies acute antimetastatic roles of dsRNA mimics

por Olmeda, David, Cerezo‐Wallis, Daniela, Mucientes, Cynthia, Calvo, Tonantzin G, Cañón, Estela, Alonso‐Curbelo, Direna, Ibarz, Nuria, Muñoz, Javier, Rodriguez‐Peralto, José L, Ortiz‐Romero, Pablo, Ortega, Sagrario, Soengas, María S
Publicado 2021

The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A

por Beucher, Anthony, Miguel-Escalada, Irene, Balboa, Diego, De Vas, Matías G., Maestro, Miguel Angel, Garcia-Hurtado, Javier, Bernal, Aina, Gonzalez-Franco, Roser, Vargiu, Pierfrancesco, Heyn, Holger, Ravassard, Philippe, Ortega, Sagrario, Ferrer, Jorge
Publicado 2022

Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias

por González-Martínez, José, Cwetsch, Andrzej W., Martínez-Alonso, Diego, López-Sainz, Luis R., Almagro, Jorge, Melati, Anna, Gómez, Jesús, Pérez-Martínez, Manuel, Megías, Diego, Boskovic, Jasminka, Gilabert-Juan, Javier, Graña-Castro, Osvaldo, Pierani, Alessandra, Behrens, Axel, Ortega, Sagrario, Malumbres, Marcos
Publicado 2021

The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity

por Lynch, Cian J., Bernad, Raquel, Calvo, Isabel, Nóbrega-Pereira, Sandrina, Ruiz, Sergio, Ibarz, Nuria, Martinez-Val, Ana, Graña-Castro, Osvaldo, Gómez-López, Gonzalo, Andrés-León, Eduardo, Espinosa Angarica, Vladimir, del Sol, Antonio, Ortega, Sagrario, Fernandez-Capetillo, Oscar, Rojo, Enrique, Munoz, Javier, Serrano, Manuel
Publicado 2018

HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer

por Kalisz, Mark, Bernardo, Edgar, Beucher, Anthony, Maestro, Miguel Angel, del Pozo, Natalia, Millán, Irene, Haeberle, Lena, Schlensog, Martin, Safi, Sami Alexander, Knoefel, Wolfram Trudo, Grau, Vanessa, de Vas, Matías, Shpargel, Karl B, Vaquero, Eva, Magnuson, Terry, Ortega, Sagrario, Esposito, Irene, Real, Francisco X, Ferrer, Jorge
Publicado 2020

Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region

por Fernández, Lara P., Deleyto-Seldas, Nerea, Colmenarejo, Gonzalo, Sanz, Alba, Wagner, Sonia, Plata-Gómez, Ana Belén, Gómez-Patiño, Mónica, Molina, Susana, Espinosa-Salinas, Isabel, Aguilar-Aguilar, Elena, Ortega, Sagrario, Graña-Castro, Osvaldo, Loria-Kohen, Viviana, Fernández-Marcos, Pablo J., Efeyan, Alejo, Ramírez de Molina, Ana
Publicado 2022