New Pharmacological Approaches for Rare Diseases

por Ortega-Gutiérrez, Silvia
Publicado 2023

Small-Molecule Therapeutic Perspectives for the Treatment of Progeria

por Macicior, Jon, Marcos-Ramiro, Beatriz, Ortega-Gutiérrez, Silvia
Publicado 2021

Targeted Disruption of the PME-1 Gene Causes Loss of Demethylated PP2A and Perinatal Lethality in Mice

por Ortega-Gutiérrez, Silvia, Leung, Donmienne, Ficarro, Scott, Peters, Eric C., Cravatt, Benjamin F.
Publicado 2008

New Trends in Aging Drug Discovery

por Benhamú, Bellinda, Martín-Fontecha, Mar, Vázquez-Villa, Henar, López-Rodríguez, María L., Ortega-Gutiérrez, Silvia
Publicado 2022

Early Endogenous Activation of CB1 and CB2 Receptors after Spinal Cord Injury Is a Protective Response Involved in Spontaneous Recovery

por Arevalo-Martin, Angel, Garcia-Ovejero, Daniel, Sierra-Palomares, Yolanda, Paniagua-Torija, Beatriz, Gonzalez-Gil, Ines, Ortega-Gutierrez, Silvia, Molina-Holgado, Eduardo
Publicado 2012

Ligand chain length drives activation of lipid G protein-coupled receptors

por Troupiotis-Tsaïlaki, Anastassia, Zachmann, Julian, González-Gil, Inés, Gonzalez, Angel, Ortega-Gutiérrez, Silvia, López-Rodríguez, Maria L., Pardo, Leonardo, Govaerts, Cedric
Publicado 2017

A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines

por Puig, Teresa, Aguilar, Helena, Cufí, Sílvia, Oliveras, Glòria, Turrado, Carlos, Ortega-Gutiérrez, Sílvia, Benhamú, Bellinda, López-Rodríguez, María Luz, Urruticoechea, Ander, Colomer, Ramon
Publicado 2011

Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes

por Camicia, Federico, Celentano, Ana M., Johns, Malcolm E., Chan, John D., Maldonado, Lucas, Vaca, Hugo, Di Siervi, Nicolás, Kamentezky, Laura, Gamo, Ana M., Ortega-Gutierrez, Silvia, Martin-Fontecha, Mar, Davio, Carlos, Marchant, Jonathan S., Rosenzvit, Mara C.
Publicado 2018

Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson–Gilford Progeria Syndrome

por Marcos-Ramiro, Beatriz, Gil-Ordóñez, Ana, Marín-Ramos, Nagore I., Ortega-Nogales, Francisco J., Balabasquer, Moisés, Gonzalo, Pilar, Khiar-Fernández, Nora, Rolas, Loïc, Barkaway, Anna, Nourshargh, Sussan, Andrés, Vicente, Martín-Fontecha, Mar, López-Rodríguez, María L., Ortega-Gutiérrez, Silvia
Publicado 2021

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA(2)), UCM-14216, Ameliorates Spinal Cord Injury in Mice

por Khiar-Fernández, Nora, Zian, Debora, Vázquez-Villa, Henar, Martínez, R. Fernando, Escobar-Peña, Andrea, Foronda-Sainz, Román, Ray, Manisha, Puigdomenech-Poch, Maria, Cincilla, Giovanni, Sánchez-Martínez, Melchor, Kihara, Yasuyuki, Chun, Jerold, López-Vales, Rubèn, López-Rodríguez, María L., Ortega-Gutiérrez, Silvia
Publicado 2022