Negative Regulators of Insulin Signaling Revealed in a Genome-Wide Functional Screen

por Huang, Shih-Min A., Hancock, Michael K., Pitman, Jeffrey L., Orth, Anthony P., Gekakis, Nicholas
Publicado 2009

Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening

por Zhou, Zongxiang, Patel, Manishha, Ng, Nicholas, Hsieh, Mindy H, Orth, Anthony P, Walker, John R, Batalov, Serge, Harris, Jennifer L, Liu, Jun
Publicado 2014

Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets

por Horman, Shane R., To, Jeremy, Lamb, John, Zoll, Jocelyn H., Leonetti, Nicole, Tu, Buu, Moran, Rita, Newlin, Robbin, Walker, John R., Orth, Anthony P.
Publicado 2017

EndoBind detects endogenous protein-protein interactions in real time

por Bill, Anke, Espinola, Sheryll, Guthy, Daniel, Haling, Jacob R., Lanter, Mylene, Lu, Min, Marelli, Anthony, Mendiola, Angelica, Miraglia, Loren, Taylor, Brandon L., Vargas, Leonardo, Orth, Anthony P., King, Frederick J.
Publicado 2021

FGFR2 Promotes Breast Tumorigenicity through Maintenance of Breast Tumor-Initiating Cells

por Kim, Sungeun, Dubrovska, Anna, Salamone, Richard J., Walker, John R., Grandinetti, Kathryn B., Bonamy, Ghislain M. C., Orth, Anthony P., Elliott, Jimmy, Porta, Diana Graus, Garcia-Echeverria, Carlos, Reddy, Venkateshwar A.
Publicado 2013

High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor

por Groot-Kormelink, Paul J., Ferrand, Sandrine, Kelley, Nicholas, Bill, Anke, Freuler, Felix, Imbert, Pierre-Eloi, Marelli, Anthony, Gerwin, Nicole, Sivilotti, Lucia G., Miraglia, Loren, Orth, Anthony P., Oakeley, Edward J., Schopfer, Ulrich, Siehler, Sandra
Publicado 2016

A proteomic analysis of atrial fibrillation in a prospective longitudinal cohort (AGES-Reykjavik study)

por Jonmundsson, Thorarinn, Steindorsdottir, Anna E, Austin, Thomas R, Frick, Elisabet A, Axelsson, Gisli T, Launer, Lenore, Psaty, Bruce M, Loureiro, Joseph, Orth, Anthony P, Aspelund, Thor, Emilsson, Valur, Floyd, James S, Jennings, Lori, Gudnason, Vilmundur, Gudmundsdottir, Valborg
Publicado 2023

Cellular Ser/Thr-Kinase Assays Using Generic Peptide Substrates

por Adams, Deanna G, Wang, Yu, Mak, Puiying A, Chyba, Jason, Shalizi, Orzala, Matzen, Jason, Anderson, Paul, Smith, Tim R, Garcia, Michael, Welch, Genevieve L, Claret, Emmanuel J, Fink, Michel, Orth, Anthony P, Caldwell, Jeremy S, Brinker, Achim
Publicado 2008

High Throughput Mutagenesis for Identification of Residues Regulating Human Prostacyclin (hIP) Receptor Expression and Function

por Bill, Anke, Rosethorne, Elizabeth M., Kent, Toby C., Fawcett, Lindsay, Burchell, Lynn, van Diepen, Michiel T., Marelli, Anthony, Batalov, Sergey, Miraglia, Loren, Orth, Anthony P., Renaud, Nicole A., Charlton, Steven J., Gosling, Martin, Gaither, L. Alex, Groot-Kormelink, Paul J.
Publicado 2014

Gene Set Enrichment in eQTL Data Identifies Novel Annotations and Pathway Regulators

por Wu, Chunlei, Delano, David L., Mitro, Nico, Su, Stephen V., Janes, Jeff, McClurg, Phillip, Batalov, Serge, Welch, Genevieve L., Zhang, Jie, Orth, Anthony P., Walker, John R., Glynne, Richard J., Cooke, Michael P., Takahashi, Joseph S., Shimomura, Kazuhiro, Kohsaka, Akira, Bass, Joseph, Saez, Enrique, Wiltshire, Tim, Su, Andrew I.
Publicado 2008

Structure-guided combination therapy to potently improve the function of mutant CFTRs

por Veit, Guido, Xu, Haijin, Dreano, Elise, Avramescu, Radu G, Bagdany, Miklos, Beitel, Lenore K, Roldan, Ariel, Hancock, Mark A, Lay, Cecilia, Li, Wei, Morin, Katelin, Gao, Sandra, Mak, Puiying A, Ainscow, Edward, Orth, Anthony P, McNamara, Peter, Edelman, Aleksander, Frenkiel, Saul, Matouk, Elias, Sermet-Gaudelus, Isabelle, Barnes, William G, Lukacs, Gergely L
Publicado 2018

Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer’s disease

por Frick, Elisabet A., Emilsson, Valur, Jonmundsson, Thorarinn, Steindorsdottir, Anna E., Johnson, Erik C. B., Puerta, Raquel, Dammer, Eric B., Shantaraman, Anantharaman, Cano, Amanda, Boada, Mercè, Valero, Sergi, García-González, Pablo, Gudmundsson, Elias F., Gudjonsson, Alexander, Loureiro, Joseph J., Orth, Anthony P., Seyfried, Nicholas T., Levey, Allan I., Ruiz, Agustin, Aspelund, Thor, Jennings, Lori L., Launer, Lenore J., Gudmundsdottir, Valborg, Gudnason, Vilmundur
Publicado 2023