Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells

por Burke, Russell T., Marcus, Joshua M., Orth, James D.
Publicado 2017

Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction

por Orth, James D., Loewer, Alexander, Lahav, Galit, Mitchison, Timothy J.
Publicado 2012

Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones

por Nahar, Asrafun, Sokolova, Vladyslava, Sekaran, Suganya, Orth, James D., Park, Soyeon
Publicado 2022

Longitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor

por Marcus, Joshua M., Burke, Russell T., DeSisto, John A., Landesman, Yosef, Orth, James D.
Publicado 2015

Regulated Interactions between Dynamin and the Actin-Binding Protein Cortactin Modulate Cell Shape

por McNiven, Mark A., Kim, Leung, Krueger, Eugene W., Orth, James D., Cao, Hong, Wong, Tai Wai
Publicado 2000

An Intermittent Live Cell Imaging Screen for siRNA Enhancers and Suppressors of a Kinesin-5 Inhibitor

por Tsui, Melody, Xie, Tiao, Orth, James D., Carpenter, Anne E., Rudnicki, Stewart, Kim, Suejong, Shamu, Caroline E., Mitchison, Timothy J.
Publicado 2009

In vivo cell cycle profiling in xenograft tumors by quantitative intravital microscopy

por Chittajallu, Deepak R, Florian, Stefan, Kohler, Rainer H, Iwamoto, Yoshiko, Orth, James D, Weissleder, Ralph, Danuser, Gaudenz, Mitchison, Timothy J
Publicado 2015