Pasteurella multocida Toxin Activates Various Heterotrimeric G Proteins by Deamidation

por Orth, Joachim H. C., Aktories, Klaus
Publicado 2010

Auranofin Inhibits the Enzyme Activity of Pasteurella multocida Toxin PMT in Human Cells and Protects Cells from Intoxication

por Carle, Stefan, Brink, Thorsten, Orth, Joachim H. C., Aktories, Klaus, Barth, Holger
Publicado 2017

Involvement of Osteocytes in the Action of Pasteurella multocida Toxin

por Heni, Hannah, Ebner, Julia K., Schmidt, Gudula, Aktories, Klaus, Orth, Joachim H. C.
Publicado 2018

Pasteurella Multocida Toxin Prevents Osteoblast Differentiation by Transactivation of the MAP-Kinase Cascade via the Gα(q/11) - p63RhoGEF - RhoA Axis

por Siegert, Peter, Schmidt, Gudula, Papatheodorou, Panagiotis, Wieland, Thomas, Aktories, Klaus, Orth, Joachim H. C.
Publicado 2013

Noncanonical G-Protein-Dependent Modulation of Osteoclast Differentiation and Bone Resorption Mediated by Pasteurella multocida Toxin

por Strack, Julia, Heni, Hannah, Gilsbach, Ralf, Hein, Lutz, Aktories, Klaus, Orth, Joachim H. C.
Publicado 2014

Genome wide CRISPR screen for Pasteurella multocida toxin (PMT) binding proteins reveals LDL Receptor Related Protein 1 (LRP1) as crucial cellular receptor

por Schoellkopf, Julian, Mueller, Thomas, Hippchen, Lena, Mueller, Teresa, Reuten, Raphael, Backofen, Rolf, Orth, Joachim, Schmidt, Gudula
Publicado 2022

The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes

por Castonguay, Jan, Orth, Joachim H. C., Müller, Thomas, Sleman, Faten, Grimm, Christian, Wahl-Schott, Christian, Biel, Martin, Mallmann, Robert Theodor, Bildl, Wolfgang, Schulte, Uwe, Klugbauer, Norbert
Publicado 2017

Salmonella Typhimurium effector SseI inhibits chemotaxis and increases host cell survival by deamidation of heterotrimeric G(i) proteins

por Brink, Thorsten, Leiss, Veronika, Siegert, Peter, Jehle, Doris, Ebner, Julia K., Schwan, Carsten, Shymanets, Aliaksei, Wiese, Sebastian, Nürnberg, Bernd, Hensel, Michael, Aktories, Klaus, Orth, Joachim H. C.
Publicado 2018

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles

por Eisenhardt, Anja E., Sprenger, Adrian, Röring, Michael, Herr, Ricarda, Weinberg, Florian, Köhler, Martin, Braun, Sandra, Orth, Joachim, Diedrich, Britta, Lanner, Ulrike, Tscherwinski, Natalja, Schuster, Simon, Dumaz, Nicolas, Schmidt, Enrico, Baumeister, Ralf, Schlosser, Andreas, Dengjel, Jörn, Brummer, Tilman
Publicado 2016

Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure

por Mayer, Sandra C., Gilsbach, Ralf, Preissl, Sebastian, Monroy Ordonez, Elsa Beatriz, Schnick, Tilman, Beetz, Nadine, Lother, Achim, Rommel, Carolin, Ihle, Hannah, Bugger, Heiko, Rühle, Frank, Schrepper, Andrea, Schwarzer, Michael, Heilmann, Claudia, Bönisch, Ulrike, Gupta, Shashi Kumar, Wilpert, Jochen, Kretz, Oliver, von Elverfeldt, Dominik, Orth, Joachim, Aktories, Klaus, Beyersdorf, Friedhelm, Bode, Christoph, Stiller, Brigitte, Krüger, Markus, Thum, Thomas, Doenst, Torsten, Stoll, Monika, Hein, Lutz
Publicado 2015