Voltage-Gated Ca(2+) Channels in Dopaminergic Substantia Nigra Neurons: Therapeutic Targets for Neuroprotection in Parkinson's Disease?

por Ortner, Nadine J.
Publicado 2021

L-type calcium channels as drug targets in CNS disorders

por Ortner, Nadine J, Striessnig, Jörg
Publicado 2015

Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?

por Striessnig, Jörg, Ortner, Nadine J., Pinggera, Alexandra
Publicado 2015

De novo CACAN1D Ca(2+) channelopathies: clinical phenotypes and molecular mechanism

por Ortner, Nadine J., Kaserer, Teresa, Copeland, J. Nathan, Striessnig, Jörg
Publicado 2020

STAC proteins associate to the IQ domain of Ca(V)1.2 and inhibit calcium-dependent inactivation

por Campiglio, Marta, Costé de Bagneaux, Pierre, Ortner, Nadine J., Tuluc, Petronel, Van Petegem, Filip, Flucher, Bernhard E.
Publicado 2018

Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca(2+) channel activators

por Ortner, Nadine J., Bock, Gabriella, Vandael, David H.F., Mauersberger, Robert, Draheim, Henning J., Gust, Ronald, Carbone, Emilio, Tuluc, Petronel, Striessnig, Jörg
Publicado 2014

Germline de novo variant F747S extends the phenotypic spectrum of CACNA1D Ca(2+) channelopathies

por Török, Ferenc, Tezcan, Kamer, Filippini, Ludovica, Fernández-Quintero, Monica L, Zanetti, Lucia, Liedl, Klaus R, Drexel, Raphaela S, Striessnig, Jörg, Ortner, Nadine J
Publicado 2022

A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated Ca(V)1.2 Calcium Channel Function

por Kaur, Gurjot, Pinggera, Alexandra, Ortner, Nadine J., Lieb, Andreas, Sinnegger-Brauns, Martina J., Yarov-Yarovoy, Vladimir, Obermair, Gerald J., Flucher, Bernhard E., Striessnig, Jörg
Publicado 2015

Biophysical classification of a CACNA1D de novo mutation as a high-risk mutation for a severe neurodevelopmental disorder

por Hofer, Nadja T., Tuluc, Petronel, Ortner, Nadine J., Nikonishyna, Yuliia V., Fernándes-Quintero, Monica L., Liedl, Klaus R., Flucher, Bernhard E., Cox, Helen, Striessnig, Jörg
Publicado 2020

RBP2 stabilizes slow Cav1.3 Ca(2+) channel inactivation properties of cochlear inner hair cells

por Ortner, Nadine J., Pinggera, Alexandra, Hofer, Nadja T., Siller, Anita, Brandt, Niels, Raffeiner, Andrea, Vilusic, Kristina, Lang, Isabelle, Blum, Kerstin, Obermair, Gerald J., Stefan, Eduard, Engel, Jutta, Striessnig, Jörg
Publicado 2019

Calcium current modulation by the γ(1) subunit depends on alternative splicing of Ca(V)1.1

por El Ghaleb, Yousra, Ortner, Nadine J., Posch, Wilfried, Fernández-Quintero, Monica L., Tuinte, Wietske E., Monteleone, Stefania, Draheim, Henning J., Liedl, Klaus R., Wilflingseder, Doris, Striessnig, Jörg, Tuluc, Petronel, Flucher, Bernhard E., Campiglio, Marta
Publicado 2022

The human channel gating–modifying A749G CACNA1D (Cav1.3) variant induces a neurodevelopmental syndrome–like phenotype in mice

por Ortner, Nadine J., Sah, Anupam, Paradiso, Enrica, Shin, Josef, Stojanovic, Strahinja, Hammer, Niklas, Haritonova, Maria, Hofer, Nadja T., Marcantoni, Andrea, Guarina, Laura, Tuluc, Petronel, Theiner, Tamara, Pitterl, Florian, Ebner, Karl, Oberacher, Herbert, Carbone, Emilio, Stefanova, Nadia, Ferraguti, Francesco, Singewald, Nicolas, Roeper, Jochen, Striessnig, Jörg
Publicado 2023