BOK-MCL1 transmembrane interactions: a challenging target for cancer therapy

por Sancho, Mónica, Orzáez, Mar
Publicado 2021

Understanding MCL1: from cellular function and regulation to pharmacological inhibition

por Sancho, Mónica, Leiva, Diego, Lucendo, Estefanía, Orzáez, Mar
Publicado 2021

Regioselective Synthesis of a Family of β‐Lactams Bearing a Triazole Moiety as Potential Apoptosis Inhibitors

por Garrido, Maria, Corredor, Miriam, Orzáez, Mar, Alfonso, Ignacio, Messeguer, Angel
Publicado 2016

Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation

por García-Laínez, Guillermo, Sancho, Mónica, García-Bayarri, Vanessa, Orzáez, Mar
Publicado 2017

Apaf1 inhibition promotes cell recovery from apoptosis

por Gortat, Anna, Sancho, Mónica, Mondragón, Laura, Messeguer, Àngel, Pérez-Payá, Enrique, Orzáez, Mar
Publicado 2015

BH3-Mimetics- and Cisplatin-Induced Cell Death Proceeds through Different Pathways Depending on the Availability of Death-Related Cellular Components

por Andreu-Fernández, Vicente, Genovés, Ainhoa, Messeguer, Angel, Orzáez, Mar, Sancho, Mónica, Pérez-Payá, Enrique
Publicado 2013

The past, present, and future of breast cancer models for nanomedicine development

por Boix-Montesinos, Paz, Soriano-Teruel, Paula M., Armiñán, Ana, Orzáez, Mar, Vicent, María J.
Publicado 2021

Polar/Ionizable Residues in Transmembrane Segments: Effects on Helix-Helix Packing

por Bañó-Polo, Manuel, Baeza-Delgado, Carlos, Orzáez, Mar, Marti-Renom, Marc A., Abad, Concepción, Mingarro, Ismael
Publicado 2012

Altered Mitochondria Morphology and Cell Metabolism in Apaf1-Deficient Cells

por Sancho, Mónica, Gortat, Anna, Herrera, Andrés E., Andreu-Fernández, Vicente, Ferraro, Elisabetta, Cecconi, Francesco, Orzáez, Mar, Pérez-Payá, Enrique
Publicado 2014

Horseradish Peroxidase-Functionalized Gold Nanoconjugates for Breast Cancer Treatment Based on Enzyme Prodrug Therapy

por Vivo-Llorca, Gema, Morellá-Aucejo, Ángela, García-Fernández, Alba, Díez, Paula, Llopis-Lorente, Antoni, Orzáez, Mar, Martínez-Máñez, Ramón
Publicado 2022

High-Capacity Mesoporous Silica Nanocarriers of siRNA for Applications in Retinal Delivery

por Ultimo, Amelia, Orzaez, Mar, Santos-Martinez, Maria J., Martínez-Máñez, Ramón, Marcos, María D., Sancenón, Félix, Ruiz-Hernández, Eduardo
Publicado 2023

Gene-Directed Enzyme Prodrug Therapy by Dendrimer-Like Mesoporous Silica Nanoparticles against Tumor Cells

por Candela-Noguera, Vicente, Vivo-Llorca, Gema, Díaz de Greñu, Borja, Alfonso, María, Aznar, Elena, Orzáez, Mar, Marcos, María Dolores, Sancenón, Félix, Martínez-Máñez, Ramón
Publicado 2021

A Polymeric Nanomedicine Diminishes Inflammatory Events in Renal Tubular Cells

por Ucero, Álvaro C., Berzal, Sergio, Ocaña-Salceda, Carlos, Sancho, Mónica, Orzáez, Mar, Messeguer, Angel, Ruiz-Ortega, Marta, Egido, Jesús, Vicent, María J., Ortiz, Alberto, Ramos, Adrián M.
Publicado 2013

Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases

por Soriano-Teruel, Paula M., García‑Laínez, Guillermo, Marco-Salvador, María, Pardo, Julián, Arias, Maykel, DeFord, Christian, Merfort, Irmgard, Vicent, María J., Pelegrín, Pablo, Sancho, Mónica, Orzáez, Mar
Publicado 2021

Nanodevices for the Efficient Codelivery of CRISPR-Cas9 Editing Machinery and an Entrapped Cargo: A Proposal for Dual Anti-Inflammatory Therapy

por García-Fernández, Alba, Vivo-Llorca, Gema, Sancho, Mónica, García-Jareño, Alicia Belén, Ramírez-Jiménez, Laura, Barber-Cano, Eloísa, Murguía, José Ramón, Orzáez, Mar, Sancenón, Félix, Martínez-Máñez, Ramón
Publicado 2022

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition

por Elena-Real, Carlos A., Díaz-Quintana, Antonio, González-Arzola, Katiuska, Velázquez-Campoy, Adrián, Orzáez, Mar, López-Rivas, Abelardo, Gil-Caballero, Sergio, De la Rosa, Miguel Á., Díaz-Moreno, Irene
Publicado 2018

Identification of NLRP3(PYD) Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity

por Moasses Ghafary, Soroush, Soriano-Teruel, Paula M., Lotfollahzadeh, Shima, Sancho, Mónica, Serrano-Candelas, Eva, Karami, Fatemeh, Barigye, Stephen J., Fernández-Pérez, Iván, Gozalbes, Rafael, Nikkhah, Maryam, Orzáez, Mar, Hosseinkhani, Saman
Publicado 2022

Apaf-1 Inhibitors Protect from Unwanted Cell Death in In Vivo Models of Kidney Ischemia and Chemotherapy Induced Ototoxicity

por Orzáez, Mar, Sancho, Mónica, Marchán, Sandra, Mondragón, Laura, Montava, Rebeca, Valero, Juan García, Landeta, Olatz, Basañez, Gorka, Carbajo, Rodrigo J., Pineda-Lucena, Antonio, Bujons, Jordi, Moure, Alejandra, Messeguer, Angel, Lagunas, Carmen, Herrero, Carmen, Pérez-Payá, Enrique
Publicado 2014

A Nanoconjugate Apaf-1 Inhibitor Protects Mesothelial Cells from Cytokine-Induced Injury

por Santamaría, Beatriz, Benito-Martin, Alberto, Ucero, Alvaro Conrado, Aroeira, Luiz Stark, Reyero, Ana, Vicent, María Jesús, Orzáez, Mar, Celdrán, Angel, Esteban, Jaime, Selgas, Rafael, Ruíz-Ortega, Marta, Cabrera, Manuel López, Egido, Jesús, Pérez-Payá, Enrique, Ortiz, Alberto
Publicado 2009

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

por Brennecke, Philip, Rasina, Dace, Aubi, Oscar, Herzog, Katja, Landskron, Johannes, Cautain, Bastien, Vicente, Francisca, Quintana, Jordi, Mestres, Jordi, Stechmann, Bahne, Ellinger, Bernhard, Brea, Jose, Kolanowski, Jacek L., Pilarski, Radosław, Orzaez, Mar, Pineda-Lucena, Antonio, Laraia, Luca, Nami, Faranak, Zielenkiewicz, Piotr, Paruch, Kamil, Hansen, Espen, von Kries, Jens P., Neuenschwander, Martin, Specker, Edgar, Bartunek, Petr, Simova, Sarka, Leśnikowski, Zbigniew, Krauss, Stefan, Lehtiö, Lari, Bilitewski, Ursula, Brönstrup, Mark, Taskén, Kjetil, Jirgensons, Aigars, Lickert, Heiko, Clausen, Mads H., Andersen, Jeanette H., Vicent, Maria J., Genilloud, Olga, Martinez, Aurora, Nazaré, Marc, Fecke, Wolfgang, Gribbon, Philip
Publicado 2019