Dynamic cycling with a unique Hsp90/Hsp70-dependent chaperone machinery and GAPDH is needed for heme insertion and activation of neuronal NO synthase

por Morishima, Yoshihiro, Lau, Miranda, Pratt, William B., Osawa, Yoichi
Publicado 2022

Amphipol-facilitated elucidation of the functional tetrameric complex of full-length cytochrome P450 CYP2B4 and NADPH-cytochrome P450 oxidoreductase

por Cheng, Shen, Bo, Zhiyuan, Hollenberg, Paul, Osawa, Yoichi, Zhang, Haoming
Publicado 2021

The Versatile Biocatalyst of Cytochrome P450 CYP102A1: Structure, Function, and Engineering

por Sun, Yudong, Huang, Xiaoqiang, Osawa, Yoichi, Chen, Yuqing Eugene, Zhang, Haoming
Publicado 2023

Computational redesign of cytochrome P450 CYP102A1 for highly stereoselective omeprazole hydroxylation by UniDesign

por Huang, Xiaoqiang, Sun, Yudong, Osawa, Yoichi, Chen, Y. Eugene, Zhang, Haoming
Publicado 2023

Bronchodilator Reversibility Occurring during the Acute Phase of Paragonimiasis westermani Infection

por Harada, Tomoya, Kawasaki, Yuji, Tsukada, Akira, Osawa, Yoichi, Takami, Hiroki, Yamaguchi, Kosuke, Kurai, Jun, Yamasaki, Akira, Shimizu, Eiji
Publicado 2018

Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells

por Maitra, Dhiman, Carter, Eric L., Richardson, Rani, Rittié, Laure, Basrur, Venkatesha, Zhang, Haoming, Nesvizhskii, Alexey I., Osawa, Yoichi, Wolf, Matthew W., Ragsdale, Stephen W., Lehnert, Nicolai, Herrmann, Harald, Omary, M. Bishr
Publicado 2019

Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation

por Wang, Adrienne M., Miyata, Yoshinari, Klinedinst, Susan, Peng, Hwei-Ming, Chua, Jason P., Komiyama, Tomoko, Li, Xiaokai, Morishima, Yoshihiro, Merry, Diane E., Pratt, William B., Osawa, Yoichi, Collins, Catherine A., Gestwicki, Jason E., Lieberman, Andrew P.
Publicado 2012