Non-Canonical Notch Signaling in Cancer and Immunity

por Ayaz, Furkan, Osborne, Barbara A.
Publicado 2014

Notch signals in the endothelium and cancer "stem-like" cells: opportunities for cancer therapy

por Gu, Jian-Wei, Rizzo, Paola, Pannuti, Antonio, Golde, Todd, Osborne, Barbara, Miele, Lucio
Publicado 2012

Breast Cancer Integrative Oncology Care and Its Costs

por Standish, Leanna J., Dowd, Fred, Sweet, Erin, Dale, Linda, Weaver, Morgan, Osborne, Barbara, Andersen, M. Robyn
Publicado 2016

Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes

por Wongchana, Wipawee, Kongkavitoon, Pornrat, Tangtanatakul, Pattarin, Sittplangkoon, Chutamath, Butta, Patcharavadee, Chawalitpong, Supatta, Pattarakankul, Thitiporn, Osborne, Barbara A., Palaga, Tanapat
Publicado 2018

Granzyme B nanoreporter for early monitoring of tumor response to immunotherapy

por Nguyen, Anh, Ramesh, Anujan, Kumar, Sahana, Nandi, Dipika, Brouillard, Anthony, Wells, Alexandria, Pobezinsky, Leonid, Osborne, Barbara, Kulkarni, Ashish A.
Publicado 2020

Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells

por Dongre, Anushka, Surampudi, Lalitha, Lawlor, Rebecca G., Fauq, Abdul H., Miele, Lucio, Golde, Todd E., Minter, Lisa M., Osborne, Barbara A.
Publicado 2014

Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses

por Hossain, Fokhrul, Majumder, Samarpan, Ucar, Deniz A., Rodriguez, Paulo C., Golde, Todd E., Minter, Lisa M., Osborne, Barbara A., Miele, Lucio
Publicado 2018

γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not

por Lessard, Christian B., Rodriguez, Edgardo, Ladd, Thomas B., Minter, Lisa M., Osborne, Barbara A., Miele, Lucio, Golde, Todd E., Ran, Yong
Publicado 2020

Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology

por Das, Pritam, Verbeeck, Christophe, Minter, Lisa, Chakrabarty, Paramita, Felsenstein, Kevin, Kukar, Thomas, Maharvi, Ghulam, Fauq, Abdul, Osborne, Barbara A, Golde, Todd E
Publicado 2012

Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells

por Sorrentino, Claudia, Hossain, Fokhrul, Rodriguez, Paulo C., Sierra, Rosa A., Pannuti, Antonio, Hatfield, Stephen, Osborne, Barbara A., Minter, Lisa M., Miele, Lucio, Morello, Silvana
Publicado 2019

Corrigendum: Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells

por Sorrentino, Claudia, Hossain, Fokhrul, Rodriguez, Paulo C., Sierra, Rosa A., Pannuti, Antonio, Hatfield, Stephen, Osborne, Barbara A., Minter, Lisa M., Miele, Lucio, Morello, Silvana
Publicado 2019

Chimeric Anti-Staphylococcal Enterotoxin B Antibodies and Lovastatin Act Synergistically to Provide In Vivo Protection against Lethal Doses of SEB

por Tilahun, Mulualem E., Kwan, Alan, Natarajan, Kannan, Quinn, Megan, Tilahun, Ashenafi Y., Xie, Chen, Margulies, David H., Osborne, Barbara A., Goldsby, Richard A., Rajagopalan, Govindarajan
Publicado 2011

γ‐Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct

por Ran, Yong, Hossain, Fokhrul, Pannuti, Antonio, Lessard, Christian B, Ladd, Gabriela Z, Jung, Joo In, Minter, Lisa M, Osborne, Barbara A, Miele, Lucio, Golde, Todd E
Publicado 2017

CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells

por Mitra, Ankita, Shanthalingam, Sudarvili, Sherman, Heather L., Singh, Khushboo, Canakci, Mine, Torres, Joe A., Lawlor, Rebecca, Ran, Yong, Golde, Todd E., Miele, Lucio, Thayumanavan, Sankaran, Minter, Lisa M., Osborne, Barbara A.
Publicado 2020

NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome

por Shin, Hyun Mu, Tilahun, Mulualem E., Cho, Ok Hyun, Chandiran, Karthik, Kuksin, Christina Arieta, Keerthivasan, Shilpa, Fauq, Abdul H., Golde, Todd E., Miele, Lucio, Thome, Margot, Osborne, Barbara A., Minter, Lisa M.
Publicado 2014

Differentiation of Pathogenic Th17 Cells Is Negatively Regulated by Let-7 MicroRNAs in a Mouse Model of Multiple Sclerosis

por Angelou, Constance C., Wells, Alexandria C., Vijayaraghavan, Jyothi, Dougan, Carey E., Lawlor, Rebecca, Iverson, Elizabeth, Lazarevic, Vanja, Kimura, Motoko Y., Peyton, Shelly R., Minter, Lisa M., Osborne, Barbara A., Pobezinskaya, Elena L., Pobezinsky, Leonid A.
Publicado 2020

Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease

por Ozay, E. Ilker, Vijayaraghavan, Jyothi, Gonzalez-Perez, Gabriela, Shanthalingam, Sudarvili, Sherman, Heather L., Garrigan, Daniel T., Chandiran, Karthik, Torres, Joe A., Osborne, Barbara A., Tew, Gregory N., Slukvin, Igor I., Macdonald, Ross A., Kelly, Kilian, Minter, Lisa M.
Publicado 2019

Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses

por Monticone, Giulia, Huang, Zhi, Csibi, Fred, Leit, Silvana, Ciccone, David, Champhekar, Ameya S., Austin, Jermaine E., Ucar, Deniz A., Hossain, Fokhrul, Ibba, Salome V., Boulares, A. Hamid, Carpino, Nicholas, Xu, Keli, Majumder, Samarpan, Osborne, Barbara A., Loh, Christine, Miele, Lucio
Publicado 2022

Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways

por Hossain, Fokhrul, Sorrentino, Claudia, Ucar, Deniz A., Peng, Yin, Matossian, Margarite, Wyczechowska, Dorota, Crabtree, Judy, Zabaleta, Jovanny, Morello, Silvana, Del Valle, Luis, Burow, Matthew, Collins-Burow, Bridgette, Pannuti, Antonio, Minter, Lisa M., Golde, Todd E., Osborne, Barbara A., Miele, Lucio
Publicado 2018

Sulindac sulfide as a non-immune suppressive γ-secretase modulator to target triple-negative breast cancer

por Hossain, Fokhrul, Ucar, Deniz A., Monticone, Giulia, Ran, Yong, Majumder, Samarpan, Larter, Kristina, Luu, Hanh, Wyczechowska, Dorota, Heidari, Soroor, Xu, Keli, Shanthalingam, Sudarvili, Matossian, Margarite, Xi, Yaguang, Burow, Matthew, Collins-Burow, Bridgette, Del Valle, Luis, Hicks, Chindo, Zabaleta, Jovanny, Golde, Todd, Osborne, Barbara, Miele, Lucio
Publicado 2023