Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies

por Aoyama, Michihiko, Hashii, Noritaka, Tsukimura, Wataru, Osumi, Kenji, Harazono, Akira, Tada, Minoru, Kiyoshi, Masato, Matsuda, Akio, Ishii-Watabe, Akiko
Publicado 2019

Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Depe...

por Kurogochi, Masaki, Mori, Masako, Osumi, Kenji, Tojino, Mami, Sugawara, Shu-ichi, Takashima, Shou, Hirose, Yuriko, Tsukimura, Wataru, Mizuno, Mamoru, Amano, Junko, Matsuda, Akio, Tomita, Masahiro, Takayanagi, Atsushi, Shoda, Shin-Ichiro, Shirai, Takashi
Publicado 2015