T-cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse

por Dong, Tobias X, Othy, Shivashankar, Jairaman, Amit, Skupsky, Jonathan, Zavala, Angel, Parker, Ian, Dynes, Joseph L, Cahalan, Michael D
Publicado 2017

Intermittent Ca(2+) signals mediated by Orai1 regulate basal T cell motility

por Dong, Tobias X, Othy, Shivashankar, Greenberg, Milton L, Jairaman, Amit, Akunwafo, Chijioke, Leverrier, Sabrina, Yu, Ying, Parker, Ian, Dynes, Joseph L, Cahalan, Michael D
Publicado 2017

Imaging regulatory T cell dynamics and suppression of T cell priming mediated by CTLA4

por Matheu, Melanie P., Othy, Shivashankar, Greenberg, Milton L., Dong, Tobias X., Schuijs, Martijn, Deswarte, Kim, Hammad, Hamida, Lambrecht, Bart N., Parker, Ian, Cahalan, Michael D.
Publicado 2015

Regulatory T cells suppress Th17 cell Ca(2+) signaling in the spinal cord during murine autoimmune neuroinflammation

por Othy, Shivashankar, Jairaman, Amit, Dynes, Joseph L., Dong, Tobias X., Tune, Cornelia, Yeromin, Andriy V., Zavala, Angel, Akunwafo, Chijioke, Chen, Fangyi, Parker, Ian, Cahalan, Michael D.
Publicado 2020

Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing

por Atcha, Hamza, Jairaman, Amit, Holt, Jesse R., Meli, Vijaykumar S., Nagalla, Raji R., Veerasubramanian, Praveen Krishna, Brumm, Kyle T., Lim, Huy E., Othy, Shivashankar, Cahalan, Michael D., Pathak, Medha M., Liu, Wendy F.
Publicado 2021

TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia

por Jairaman, Amit, McQuade, Amanda, Granzotto, Alberto, Kang, You Jung, Chadarevian, Jean Paul, Gandhi, Sunil, Parker, Ian, Smith, Ian, Cho, Hansang, Sensi, Stefano L, Othy, Shivashankar, Blurton-Jones, Mathew, Cahalan, Michael D
Publicado 2022

Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4(+) T cell responses

por Jairaman, Amit, Othy, Shivashankar, Dynes, Joseph L., Yeromin, Andriy V., Zavala, Angel, Greenberg, Milton L., Nourse, Jamison L., Holt, Jesse R., Cahalan, Stuart M., Marangoni, Francesco, Parker, Ian, Pathak, Medha M., Cahalan, Michael D.
Publicado 2021

Calcium Dynamics in Astrocytes During Cell Injury

por Wakida, Nicole M., Gomez-Godinez, Veronica, Li, Huayan, Nguyen, Jessica, Kim, Edward K., Dynes, Joseph L., Othy, Shivashankar, Lau, Alice L., Ding, Peng, Shi, Linda, Carmona, Christopher, Thompson, Leslie M., Cahalan, Michael D., Berns, Michael W.
Publicado 2020

Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses

por Bolton, Jessica L., Short, Annabel K., Othy, Shivashankar, Kooiker, Cassandra L., Shao, Manlin, Gunn, Benjamin G., Beck, Jaclyn, Bai, Xinglong, Law, Stephanie M., Savage, Julie C., Lambert, Jeremy J., Belelli, Delia, Tremblay, Marie-Ève, Cahalan, Michael D., Baram, Tallie Z.
Publicado 2022

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

por Coulis, Gerald, Jaime, Diego, Guerrero-Juarez, Christian, Kastenschmidt, Jenna M., Farahat, Philip K., Nguyen, Quy, Pervolarakis, Nicholas, McLinden, Katherine, Thurlow, Lauren, Movahedi, Saba, Duarte, Jorge, Sorn, Andrew, Montoya, Elizabeth, Mozaffar, Izza, Dragan, Morgan, Othy, Shivashankar, Joshi, Trupti, Hans, Chetan P., Kimonis, Virginia, MacLean, Adam L., Nie, Qing, Wallace, Lindsay M., Harper, Scott Q., Mozaffar, Tahseen, Hogarth, Marshall W., Bhattacharya, Surajit, Jaiswal, Jyoti K., Golann, David R., Su, Qi, Kessenbrock, Kai, Stec, Michael, Spencer, Melissa J., Zamudio, Jesse R., Villalta, S. Armando
Publicado 2023

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

por Coulis, Gerald, Jaime, Diego, Guerrero-Juarez, Christian, Kastenschmidt, Jenna M., Farahat, Philip K., Nguyen, Quy, Pervolarakis, Nicholas, McLinden, Katherine, Thurlow, Lauren, Movahedi, Saba, Hughes, Brandon S., Duarte, Jorge, Sorn, Andrew, Montoya, Elizabeth, Mozaffar, Izza, Dragan, Morgan, Othy, Shivashankar, Joshi, Trupti, Hans, Chetan P., Kimonis, Virginia, MacLean, Adam L., Nie, Qing, Wallace, Lindsay M., Harper, Scott Q., Mozaffar, Tahseen, Hogarth, Marshall W., Bhattacharya, Surajit, Jaiswal, Jyoti K., Golann, David R., Su, Qi, Kessenbrock, Kai, Stec, Michael, Spencer, Melissa J., Zamudio, Jesse R., Villalta, S. Armando
Publicado 2023