Mitochondrial DNA as an inflammatory mediator in cardiovascular diseases

por Nakayama, Hiroyuki, Otsu, Kinya
Publicado 2018

Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling

por Kase, Yoshitaka, Otsu, Kinya, Shimazaki, Takuya, Okano, Hideyuki
Publicado 2019

Exercise Provides Direct Biphasic Cardioprotection via Manganese Superoxide Dismutase Activation

por Yamashita, Nobushige, Hoshida, Shiro, Otsu, Kinya, Asahi, Michio, Kuzuya, Tsunehiko, Hori, Masatsugu
Publicado 1999

A Mammalian Mitophagy Receptor, Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy

por Murakawa, Tomokazu, Okamoto, Koji, Omiya, Shigemiki, Taneike, Manabu, Yamaguchi, Osamu, Otsu, Kinya
Publicado 2019

p38α signaling programs dendritic cells to drive T(H)17 cell differentiation and autoimmune inflammation

por Huang, Gonghua, Wang, Yanyan, Vogel, Peter, Kanneganti, Thirumala-Devi, Otsu, Kinya, Chi, Hongbo
Publicado 2012

Targeted ablation of p38α MAPK suppresses denervation-induced muscle atrophy

por Yuasa, Kazuki, Okubo, Kazumasa, Yoda, Masaki, Otsu, Kinya, Ishii, Yasuyuki, Nakamura, Masaya, Itoh, Yoshiki, Horiuchi, Keisuke
Publicado 2018

Calpain-mediated proteolytic production of free amino acids in vascular endothelial cells augments obesity-induced hepatic steatosis

por Akasu, Risako, Miyazaki, Takuro, Elhussiny, Mohamed Z., Sugiura, Yuki, Tomitsuka, Yuki, Haraguchi, Shogo, Otsu, Kinya, Chowdhury, Vishwajit S., Miyazaki, Akira
Publicado 2022

p38α plays differential roles in hematopoietic stem cell activity dependent on aging contexts

por Sorimachi, Yuriko, Karigane, Daiki, Ootomo, Yukako, Kobayashi, Hiroshi, Morikawa, Takayuki, Otsu, Kinya, Kubota, Yoshiaki, Okamoto, Shinichiro, Goda, Nobuhito, Takubo, Keiyo
Publicado 2021

Ablation of Toll-like receptor 9 attenuates myocardial ischemia/reperfusion injury in mice

por Kitazume-Taneike, Rika, Taneike, Manabu, Omiya, Shigemiki, Misaka, Tomofumi, Nishida, Kazuhiko, Yamaguchi, Osamu, Akira, Shizuo, Shattock, Michael J., Sakata, Yasushi, Otsu, Kinya
Publicado 2019

FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice

por Misaka, Tomofumi, Murakawa, Tomokazu, Nishida, Kazuhiko, Omori, Yosuke, Taneike, Manabu, Omiya, Shigemiki, Molenaar, Chris, Uno, Yoshihiro, Yamaguchi, Osamu, Takeda, Junji, Shah, Ajay M., Otsu, Kinya
Publicado 2018

Administration of a TLR9 Inhibitor Attenuates the Development and Progression of Heart Failure in Mice

por Ueda, Hiromichi, Yamaguchi, Osamu, Taneike, Manabu, Akazawa, Yasuhiro, Wada-Kobayashi, Haruko, Sugihara, Ryuta, Yorifuji, Hiroki, Nakayama, Hiroyuki, Omiya, Shigemiki, Murakawa, Tomokazu, Sakata, Yasushi, Otsu, Kinya
Publicado 2019

Cytokine mRNA Degradation in Cardiomyocytes Restrains Sterile Inflammation in Pressure-Overloaded Hearts

por Omiya, Shigemiki, Omori, Yosuke, Taneike, Manabu, Murakawa, Tomokazu, Ito, Jumpei, Tanada, Yohei, Nishida, Kazuhiko, Yamaguchi, Osamu, Satoh, Takashi, Shah, Ajay M., Akira, Shizuo, Otsu, Kinya
Publicado 2020

ROS amplification drives mouse spermatogonial stem cell self-renewal

por Morimoto, Hiroko, Kanastu-Shinohara, Mito, Ogonuki, Narumi, Kamimura, Satoshi, Ogura, Atsuo, Yabe-Nishimura, Chihiro, Mori, Yoshifumi, Morimoto, Takeshi, Watanabe, Satoshi, Otsu, Kinya, Yamamoto, Takuya, Shinohara, Takashi
Publicado 2019

P38α MAPK is a gatekeeper of uterine progesterone responsiveness at peri-implantation via Ube3c-mediated PGR degradation

por Tang, Yedong, Qiu, Jingtao, Tang, Zhenzhou, Li, Gaizhen, Gu, Mengqing, Wang, Yang, Bao, Haili, Deng, Wenbo, Lu, Zhongxian, Otsu, Kinya, Wang, Zhengchao, Wang, Haibin, Kong, Shuangbo
Publicado 2022

mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the...

por Taneike, Manabu, Nishida, Kazuhiko, Omiya, Shigemiki, Zarrinpashneh, Elham, Misaka, Tomofumi, Kitazume-Taneike, Rika, Austin, Ruth, Takaoka, Minoru, Yamaguchi, Osamu, Gambello, Michael J., Shah, Ajay M., Otsu, Kinya
Publicado 2016

Mitochondrial DNA That Escapes from Autophagy Causes Inflammation and Heart Failure

por Oka, Takafumi, Hikoso, Shungo, Yamaguchi, Osamu, Taneike, Manabu, Takeda, Toshihiro, Tamai, Takahito, Oyabu, Jota, Murakawa, Tomokazu, Nakayama, Hiroyuki, Nishida, Kazuhiko, Akira, Shizuo, Yamamoto, Akitsugu, Komuro, Issei, Otsu, Kinya
Publicado 2012

Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice

por Ito, Jumpei, Omiya, Shigemiki, Rusu, Mara-Camelia, Ueda, Hiromichi, Murakawa, Tomokazu, Tanada, Yohei, Abe, Hajime, Nakahara, Kazuki, Asahi, Michio, Taneike, Manabu, Nishida, Kazuhiko, Shah, Ajay M, Otsu, Kinya
Publicado 2021

Rubicon-regulated beta-1 adrenergic receptor recycling protects the heart from pressure overload

por Akazawa, Yasuhiro, Taneike, Manabu, Ueda, Hiromichi, Kitazume-Taneike, Rika, Murakawa, Tomokazu, Sugihara, Ryuta, Yorifuji, Hiroki, Nishida, Hiroki, Mine, Kentaro, Hioki, Ayana, Omiya, Shigemiki, Nakayama, Hiroyuki, Yamaguchi, Osamu, Yoshimori, Tamotsu, Sakata, Yasushi, Otsu, Kinya
Publicado 2022

The kinase p38α functions in dendritic cells to regulate Th2-cell differentiation and allergic inflammation

por Han, Miaomiao, Ma, Jingyu, Ouyang, Suidong, Wang, Yanyan, Zheng, Tingting, Lu, Peishan, Zheng, Zihan, Zhao, Weiheng, Li, Hongjin, Wu, Yun, Zhang, Baohua, Hu, Ran, Otsu, Kinya, Liu, Xinguang, Wan, Ying, Li, Huabin, Huang, Gonghua
Publicado 2022

Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction

por Hayakawa, Morisada, Hayakawa, Hiroko, Petrova, Tsvetana, Ritprajak, Patcharee, Sutavani, Ruhcha V., Jiménez-Andrade, Guillermina Yanek, Sano, Yasuyo, Choo, Min-Kyung, Seavitt, John, Venigalla, Ram K. C., Otsu, Kinya, Georgopoulos, Katia, Arthur, J. Simon C., Park, Jin Mo
Publicado 2017