The role of osteoblasts in bone metastasis

por Ottewell, Penelope D
Publicado 2016

The role of IL-1B in breast cancer bone metastasis

por Tulotta, Claudia, Ottewell, Penelope
Publicado 2018

Chemotherapy resistance and stemness in mitotically quiescent human breast cancer cells identified by fluorescent dye retention

por Quayle, Lewis A., Ottewell, Penelope D., Holen, Ingunn
Publicado 2018

The differential anti-tumour effects of zoledronic acid in breast cancer – evidence for a role of the activin signaling pathway

por Wilson, Caroline, Ottewell, Penelope, Coleman, Robert E, Holen, Ingunn
Publicado 2015

Transcriptomic Profiling Reveals Novel Candidate Genes and Signalling Programs in Breast Cancer Quiescence and Dormancy †

por Quayle, Lewis A., Spicer, Amy, Ottewell, Penelope D., Holen, Ingunn
Publicado 2021

The kinetochore protein Cenp-F is a potential novel target for zoledronic acid in breast cancer cells

por Brown, Hannah K, Ottewell, Penelope D, Coleman, Robert E, Holen, Ingunn
Publicado 2011

The IL‐1/IL‐1R axis induces greater fibroblast‐derived chemokine release in human papillomavirus‐negative compared to positive oropharyngeal cancer

por Al‐Sahaf, Sarmad, Hunter, Keith D., Bolt, Robert, Ottewell, Penelope D., Murdoch, Craig
Publicado 2018

Oestrogen and zoledronic acid driven changes to the bone and immune environments: Potential mechanisms underlying the differential anti-tumour effects of zoledronic acid in pre- an...

por George, Christopher N., Canuas-Landero, Victor, Theodoulou, Elizavet, Muthana, Munitta, Wilson, Caroline, Ottewell, Penelope
Publicado 2020

IL-1 drives breast cancer growth and bone metastasis in vivo

por Holen, Ingunn, Lefley, Diane V., Francis, Sheila E., Rennicks, Sarah, Bradbury, Steven, Coleman, Robert E., Ottewell, Penelope
Publicado 2016

The bone metastasis niche in breast cancer-potential overlap with the haematopoietic stem cell niche in vivo

por Allocca, Gloria, Hughes, Russell, Wang, Ning, Brown, Hannah K, Ottewell, Penelope D, Brown, Nicola J, Holen, Ingunn
Publicado 2019

Increased Abundance of Tumour-Associated Neutrophils in HPV-Negative Compared to HPV-Positive Oropharyngeal Squamous Cell Carcinoma Is Mediated by IL-1R Signalling

por Al-Sahaf, Sarmad, Hendawi, Naeima B., Ollington, Bethany, Bolt, Robert, Ottewell, Penelope D., Hunter, Keith D., Murdoch, Craig
Publicado 2021

Oestradiol Contributes to Differential Antitumour Effects of Adjuvant Zoledronic Acid Observed Between Pre- and Post-Menopausal Women

por Canuas-Landero, Victor G., George, Christopher N., Lefley, Diane V., Corness, Hannah, Muthana, Munitta, Wilson, Caroline, Ottewell, Penelope D.
Publicado 2021

Loss of plakoglobin promotes decreased cell-cell contact, increased invasion, and breast cancer cell dissemination in vivo

por Holen, Ingunn, Whitworth, Jacob, Nutter, Faith, Evans, Alyson, Brown, Hannah K, Lefley, Diane V, Barbaric, Ivana, Jones, Mark, Ottewell, Penelope D
Publicado 2012

Erratum to: Loss of plakoglobin promotes cell-cell contact, increased invasion and breast cancer cell dissemination in vivo

por Holen, Ingunn, Whitworth, Jacob, Nutter, Faith, Evans, Alyson, Brown, Hannah K., Lefley, Diane V., Barbaric, Ivana, Jones, Mark, Ottewell, Penelope D.
Publicado 2017

Parathyroid Hormone (PTH) Increases Skeletal Tumour Growth and Alters Tumour Distribution in an In Vivo Model of Breast Cancer

por Brown, Hannah K., Allocca, Gloria, Ottewell, Penelope D., Wang, Ning, Brown, Nicola J., Croucher, Peter I., Eaton, Colby L., Holen, Ingunn
Publicado 2018

The CDK4/6 Inhibitor Palbociclib Inhibits Estrogen-Positive and Triple Negative Breast Cancer Bone Metastasis In Vivo

por Saleh, Lubaid, Ottewell, Penelope D., Brown, Janet E., Wood, Steve L., Brown, Nichola J., Wilson, Caroline, Park, Catherine, Ali, Simak, Holen, Ingunn
Publicado 2023

Osteoblast-Derived Paracrine and Juxtacrine Signals Protect Disseminated Breast Cancer Cells from Stress

por Hughes, Russell, Chen, Xinyue, Cowley, Natasha, Ottewell, Penelope D., Hawkins, Rhoda J., Hunter, Keith D., Hobbs, Jamie K., Brown, Nicola J., Holen, Ingunn
Publicado 2021

Novel Methods of Targeting IL-1 Signalling for the Treatment of Breast Cancer Bone Metastasis

por Zhou, Jiabao, Down, Jennifer M., George, Christopher N., Murphy, Jessica, Lefley, Diane V., Tulotta, Claudia, Alsharif, Marwa A., Leach, Michael, Ottewell, Penelope D.
Publicado 2022

The frequency of osteolytic bone metastasis is determined by conditions of the soil, not the number of seeds; evidence from in vivo models of breast and prostate cancer

por Wang, Ning, Reeves, Kimberley J., Brown, Hannah K., Fowles, Anne C M, Docherty, Freyja E., Ottewell, Penelope D., Croucher, Peter I., Holen, Ingunn, Eaton, Colby L.
Publicado 2015

Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts

por Lefley, Diane, Howard, Faith, Arshad, Fawaz, Bradbury, Steven, Brown, Hannah, Tulotta, Claudia, Eyre, Rachel, Alférez, Denis, Wilkinson, J. Mark, Holen, Ingunn, Clarke, Robert B., Ottewell, Penelope
Publicado 2019