Unravelling morphoea aetiopathogenesis by next-generation sequencing of paired skin biopsies

por Saracino, Amanda M., Kelberman, Daniel, Otto, Georg W., Gagunashvili, Andrey, Abraham, David J., Denton, Christopher P.
Publicado 2023

The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes

por Shimizu, Hirohito, Langenbacher, Adam D, Huang, Jie, Wang, Kevin, Otto, Georg, Geisler, Robert, Wang, Yibin, Chen, Jau-Nian
Publicado 2017

Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance

por Otto, Georg W., Kaisaki, Pamela J., Brial, Francois, Le Lay, Aurélie, Cazier, Jean-Baptiste, Mott, Richard, Gauguier, Dominique
Publicado 2019

Graded Elevation of c-Jun in Schwann Cells In Vivo: Gene Dosage Determines Effects on Development, Remyelination, Tumorigenesis, and Hypomyelination

por Fazal, Shaline V., Gomez-Sanchez, Jose A., Wagstaff, Laura J., Musner, Nicolo, Otto, Georg, Janz, Martin, Mirsky, Rhona, Jessen, Kristján R.
Publicado 2017

Causes and Consequences of Chromatin Variation between Inbred Mice

por Hosseini, Mona, Goodstadt, Leo, Hughes, Jim R., Kowalczyk, Monika S., de Gobbi, Marco, Otto, Georg W., Copley, Richard R., Mott, Richard, Higgs, Douglas R., Flint, Jonathan
Publicado 2013

The Light Responsive Transcriptome of the Zebrafish: Function and Regulation

por Weger, Benjamin D., Sahinbas, Meltem, Otto, Georg W., Mracek, Philipp, Armant, Olivier, Dolle, Dirk, Lahiri, Kajori, Vallone, Daniela, Ettwiller, Laurence, Geisler, Robert, Foulkes, Nicholas S., Dickmeis, Thomas
Publicado 2011

RARE-08. Profiling of recurrent adamantinomatous cranionpharyngioma confirms the activation of the MAPK pathway and identifies copy number aberrations in relapsed tumours

por Apps, John, Pickles, Jessica, Stone, Thomas, Chalker, Jane, Ogunbiyi, Olumide, Schwalbe, Edward, Brandner, Sebastian, Otto, Georg, Castellano, Sergi, Jacques, Thomas, Deutschbein, Timo, Martinez-Barbera, Juan Pedro
Publicado 2022

Genetic Control of Differential Acetylation in Diabetic Rats

por Kaisaki, Pamela J., Otto, Georg W., McGouran, Joanna F., Toubal, Amine, Argoud, Karène, Waller-Evans, Helen, Finlay, Clare, Caldérari, Sophie, Bihoreau, Marie-Thérèse, Kessler, Benedikt M., Gauguier, Dominique, Mott, Richard
Publicado 2014

Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression

por Kaisaki, Pamela J., Otto, Georg W., Argoud, Karène, Collins, Stephan C., Wallis, Robert H., Wilder, Steven P., Yau, Anthony C. Y., Hue, Christophe, Calderari, Sophie, Bihoreau, Marie-Thérèse, Cazier, Jean-Baptiste, Mott, Richard, Gauguier, Dominique
Publicado 2016

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells

por Chagraoui, Hedia, Kristiansen, Maiken S., Ruiz, Juan Pablo, Serra-Barros, Ana, Richter, Johanna, Hall-Ponselé, Elisa, Gray, Nicki, Waithe, Dominic, Clark, Kevin, Hublitz, Philip, Repapi, Emmanouela, Otto, Georg, Sopp, Paul, Taylor, Stephen, Thongjuea, Supat, Vyas, Paresh, Porcher, Catherine
Publicado 2018

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay

por Juban, Gaëtan, Sakakini, Nathalie, Chagraoui, Hedia, Hernandez, David Cruz, Cheng, Qian, Soady, Kelly, Stoilova, Bilyana, Garnett, Catherine, Waithe, Dominic, Otto, Georg, Doondeea, Jessica, Usukhbayar, Batchimeg, Karkoulia, Elena, Alexiou, Maria, Strouboulis, John, Morrissey, Edward, Roberts, Irene, Porcher, Catherine, Vyas, Paresh
Publicado 2020

Role of CD14+ monocyte-derived oxidised mitochondrial DNA in the inflammatory interferon type 1 signature in juvenile dermatomyositis

por Wilkinson, Meredyth G Ll, Moulding, Dale, McDonnell, Thomas C R, Orford, Michael, Wincup, Chris, Ting, Joanna Y J, Otto, Georg W, Restuadi, Restuadi, Kelberman, Daniel, Papadopoulou, Charalampia, Castellano, Sergi, Eaton, Simon, Deakin, Claire T, Rosser, Elizabeth C, Wedderburn, Lucy R
Publicado 2023

Heterogeneity of human lympho-myeloid progenitors at the single cell level

por Karamitros, Dimitris, Stoilova, Bilyana, Aboukhalil, Zahra, Hamey, Fiona, Reinisch, Andreas, Samitsch, Marina, Quek, Lynn, Otto, Georg, Repapi, Emmanouela, Doondeea, Jessica, Usukhbayar, Batchimeg, Calvo, Julien, Taylor, Stephen, Goardon, Nicolas, Six, Emmanuelle, Pflumio, Francoise, Porcher, Catherine, Majeti, Ravindra, Gottgens, Berthold, Vyas, Paresh
Publicado 2017

De-Suppression of Mesenchymal Cell Identities and Variable Phenotypic Outcomes Associated with Knockout of Bbs1

por Freke, Grace Mercedes, Martins, Tiago, Davies, Rosalind Jane, Beyer, Tina, Seda, Marian, Peskett, Emma, Haq, Naila, Prasai, Avishek, Otto, Georg, Jeyabalan Srikaran, Jeshmi, Hernandez, Victor, Diwan, Gaurav D., Russell, Robert B., Ueffing, Marius, Huranova, Martina, Boldt, Karsten, Beales, Philip L., Jenkins, Dagan
Publicado 2023

Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment

por Brial, Francois, Le Lay, Aurélie, Hedjazi, Lyamine, Tsang, Tsz, Fearnside, Jane F., Otto, Georg W., Alzaid, Fawaz, Wilder, Steven P., Venteclef, Nicolas, Cazier, Jean-Baptiste, Nicholson, Jeremy K., Day, Chris, Burt, Alastair D., Gut, Ivo G., Lathrop, Mark, Dumas, Marc-Emmanuel, Gauguier, Dominique
Publicado 2019

Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun

por Wagstaff, Laura J, Gomez-Sanchez, Jose A, Fazal, Shaline V, Otto, Georg W, Kilpatrick, Alastair M, Michael, Kirolos, Wong, Liam YN, Ma, Ki H, Turmaine, Mark, Svaren, John, Gordon, Tessa, Arthur-Farraj, Peter, Velasco-Aviles, Sergio, Cabedo, Hugo, Benito, Cristina, Mirsky, Rhona, Jessen, Kristjan R
Publicado 2021

CD19(+)CD24(hi)CD38(hi) B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α

por Piper, Christopher J. M., Wilkinson, Meredyth G. Ll., Deakin, Claire T., Otto, Georg W., Dowle, Stefanie, Duurland, Chantal L., Adams, Stuart, Marasco, Emiliano, Rosser, Elizabeth C., Radziszewska, Anna, Carsetti, Rita, Ioannou, Yiannis, Beales, Philip L., Kelberman, Daniel, Isenberg, David A., Mauri, Claudia, Nistala, Kiran, Wedderburn, Lucy R.
Publicado 2018

Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series

por Dumas, Marc-Emmanuel, Domange, Céline, Calderari, Sophie, Martínez, Andrea Rodríguez, Ayala, Rafael, Wilder, Steven P., Suárez-Zamorano, Nicolas, Collins, Stephan C., Wallis, Robert H., Gu, Quan, Wang, Yulan, Hue, Christophe, Otto, Georg W., Argoud, Karène, Navratil, Vincent, Mitchell, Steve C., Lindon, John C., Holmes, Elaine, Cazier, Jean-Baptiste, Nicholson, Jeremy K., Gauguier, Dominique
Publicado 2016

RARE-22 Characterizing the landscape of structural variants in adamantinomatous craniopharyngioma

por Jomaa, Danny, Khadka, Prasidda, Novikov, Dana, Condurat, Alexandra L, Tsai, Jessica W, Dubois, Frank, Zhang, Shu, Zhou, Kevin, Gold, Rose, Sousa, Cecilia, Vogelzang, Jayne, Prince, Eric, Lu, Sophie, Slivova, Veronika, Otto, Georg W, Hereza, Sergi Castellano, Ashley, David, Cohen-Gadol, Aaron A, Thompson, Eric, Beroukhim, Rameen, Apps, John, Martinez-Barbera, Juan Pedro, Hankinson, Todd, Bandopadhayay, Pratiti
Publicado 2022