Myeloid liver kinase B1 contributes to lung inflammation induced by lipoteichoic acid but not by viable Streptococcus pneumoniae

por Pereverzeva, Liza, Otto, Natasja A., Roelofs, Joris J. T. H., de Vos, Alex F., van der Poll, Tom
Publicado 2022

Association of Myeloid Liver Kinase B1 Depletion With a Reduction in Alveolar Macrophage Numbers and an Impaired Host Defense During Gram-Negative Pneumonia

por Otto, Natasja A, de Vos, Alex F, van Heijst, Jeroen W J, Roelofs, Joris J T H, van der Poll, Tom
Publicado 2020

Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia

por Brands, Xanthe, Haak, Bastiaan W., Klarenbeek, Augustijn M., Otto, Natasja A., Faber, Daniël R., Lutter, René, Scicluna, Brendon P., Wiersinga, W. Joost, van der Poll, Tom
Publicado 2020

Corrigendum: Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia

por Brands, Xanthe, Haak, Bastiaan W., Klarenbeek, Augustijn M., Otto, Natasja A., Faber, Daniël R., Lutter, René, Scicluna, Brendon P., Wiersinga, W. Joost, van der Poll, Tom
Publicado 2020

Hypoxia-Inducible Factor-1α in Macrophages, but Not in Neutrophils, Is Important for Host Defense during Klebsiella pneumoniae-Induced Pneumosepsis

por Otto, Natasja A., Pereverzeva, Liza, Leopold, Valentine, Ramirez-Moral, Ivan, Roelofs, Joris J. T. H., van Heijst, Jeroen W. J., de Vos, Alex F., van der Poll, Tom
Publicado 2021

Rectal microbiota are coupled with altered cytokine production capacity following community-acquired pneumonia hospitalization

por Kullberg, Robert F.J., Brands, Xanthe, Klarenbeek, Augustijn M., Butler, Joe M., Otto, Natasja A., Faber, Daniël R., Scicluna, Brendon P., van der Poll, Tom, Wiersinga, W. Joost, Haak, Bastiaan W.
Publicado 2022

HIF-1α Stabilization in Flagellin-Stimulated Human Bronchial Cells Impairs Barrier Function

por Ramirez-Moral, Ivan, Ferreira, Bianca L., Butler, Joe M., van Weeghel, Michel, Otto, Natasja A., de Vos, Alex F., Yu, Xiao, de Jong, Menno D., Houtkooper, Riekelt H., van der Poll, Tom
Publicado 2022

The Long Non-Coding Antisense RNA JHDM1D-AS1 Regulates Inflammatory Responses in Human Monocytes

por Malmström, Erik, Khan, Hina N., Veer, Cornelis van ‘t, Stunnenberg, Melissa, Meijer, Mariska T., Matsumoto, Hisatake, Otto, Natasja A., Geijtenbeek, Teunis B. H., de Vos, Alex F., van der Poll, Tom, Scicluna, Brendon P.
Publicado 2022

An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration

por Brands, Xanthe, Haak, Bastiaan W., Klarenbeek, Augustijn M., Butler, Joe, Uhel, Fabrice, Qin, Wanhai, Otto, Natasja A., Jakobs, Marja E., Faber, Daniël R., Lutter, René, Wiersinga, W. Joost, van der Poll, Tom, Scicluna, Brendon P.
Publicado 2021

Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia

por Schuurman, Alex R., Butler, Joe M., Michels, Erik H.A., Otto, Natasja A., Brands, Xanthe, Haak, Bastiaan W., Uhel, Fabrice, Klarenbeek, Augustijn M., Faber, Daniël R., Schomakers, Bauke V., van Weeghel, Michel, de Vos, Alex F., Scicluna, Brendon P., Houtkooper, Riekelt H., Wiersinga, W. Joost, van der Poll, Tom
Publicado 2023

Association of Hyperferritinemia With Distinct Host Response Aberrations in Patients With Community-Acquired Pneumonia

por Brands, Xanthe, van Engelen, Tjitske S R, de Vries, Floris M C, Haak, Bastiaan W, Klarenbeek, Augustijn M, Kanglie, Maadrika M N P, van den Berk, Inge A H, Schuurman, Alex R, Peters-Sengers, Hessel, Otto, Natasja A, Faber, Daniël R, Lutter, René, Scicluna, Brendon P, Stoker, Jaap, Prins, Jan M, Joost Wiersinga, W, van der Poll, Tom
Publicado 2022