Neural Stem Cell Plasticity: Advantages in Therapy for the Injured Central Nervous System

por Ottoboni, Linda, Merlini, Arianna, Martino, Gianvito
Publicado 2017

Therapeutic Plasticity of Neural Stem Cells

por Ottoboni, Linda, von Wunster, Beatrice, Martino, Gianvito
Publicado 2020

Targeting PTB for Glia-to-Neuron Reprogramming In Vitro and In Vivo for Therapeutic Development in Neurological Diseases

por Contardo, Matilde, De Gioia, Roberta, Gagliardi, Delia, Comi, Giacomo Pietro, Ottoboni, Linda, Nizzardo, Monica, Corti, Stefania
Publicado 2022

Siponimod (BAF312) Activates Nrf2 While Hampering NFκB in Human Astrocytes, and Protects From Astrocyte-Induced Neurodegeneration

por Colombo, Emanuela, Bassani, Claudia, De Angelis, Anthea, Ruffini, Francesca, Ottoboni, Linda, Comi, Giancarlo, Martino, Gianvito, Farina, Cinthia
Publicado 2020

Antiarrhythmic drug loading at home using remote monitoring: a virtual feasibility study during COVID-19 social distancing

por Shah, Rajan L, Kapoor, Ridhima, Bonnett, Colleen, Ottoboni, Linda K, Tacklind, Christine, Tsiperfal, Angela, Perez, Marco V
Publicado 2021

Heparin Precursors with Reduced Anticoagulant Properties Retain Antiviral and Protective Effects That Potentiate the Efficacy of Sofosbuvir against Zika Virus Infection in Human Ne...

por Pagani, Isabel, Ottoboni, Linda, Panina-Bordignon, Paola, Martino, Gianvito, Poli, Guido, Taylor, Sarah, Turnbull, Jeremy E., Yates, Edwin, Vicenzi, Elisa
Publicado 2023

Differentiation of Sendai Virus-Reprogrammed iPSC into β Cells, Compared with Human Pancreatic Islets and Immortalized β Cell Line

por Pellegrini, Silvia, Manenti, Fabio, Chimienti, Raniero, Nano, Rita, Ottoboni, Linda, Ruffini, Francesca, Martino, Gianvito, Ravassard, Philippe, Piemonti, Lorenzo, Sordi, Valeria
Publicado 2018

iAstrocytes do not restrain T cell proliferation in vitro

por Colombo, Emanuela, De Angelis, Anthea, Bassani, Claudia, Ruffini, Francesca, Ottoboni, Linda, Garzetti, Livia, Finardi, Annamaria, Martino, Gianvito, Furlan, Roberto, Farina, Cinthia
Publicado 2023

Laquinimod Modulates Human Astrocyte Function and Dampens Astrocyte-Induced Neurotoxicity during Inflammation

por Colombo, Emanuela, Pascente, Rosaria, Triolo, Daniela, Bassani, Claudia, De Angelis, Anthea, Ruffini, Francesca, Ottoboni, Linda, Comi, Giancarlo, Martino, Gianvito, Farina, Cinthia
Publicado 2020

Identification of Novel Biomarkers of Spinal Muscular Atrophy and Therapeutic Response by Proteomic and Metabolomic Profiling of Human Biological Fluid Samples

por Meneri, Megi, Abati, Elena, Gagliardi, Delia, Faravelli, Irene, Parente, Valeria, Ratti, Antonia, Verde, Federico, Ticozzi, Nicola, Comi, Giacomo P., Ottoboni, Linda, Corti, Stefania
Publicado 2023

Heparin Protects Human Neural Progenitor Cells from Zika Virus-Induced Cell Death While Preserving Their Differentiation into Mature Neuroglial Cells

por Pagani, Isabel, Ottoboni, Linda, Podini, Paola, Ghezzi, Silvia, Brambilla, Elena, Bezukladova, Svetlana, Corti, Davide, Bianchi, Marco Emilio, Capobianchi, Maria Rosaria, Poli, Guido, Panina-Bordignon, Paola, Yates, Edwin A., Martino, Gianvito, Vicenzi, Elisa
Publicado 2022

Multi-omics profiling of CSF from spinal muscular atrophy type 3 patients after nusinersen treatment: a 2-year follow-up multicenter retrospective study

por Faravelli, Irene, Gagliardi, Delia, Abati, Elena, Meneri, Megi, Ongaro, Jessica, Magri, Francesca, Parente, Valeria, Petrozzi, Lucia, Ricci, Giulia, Farè, Fiorenza, Garrone, Giulia, Fontana, Manuela, Caruso, Donatella, Siciliano, Gabriele, Comi, Giacomo Pietro, Govoni, Alessandra, Corti, Stefania, Ottoboni, Linda
Publicado 2023

Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis

por Muzio, Luca, Sirtori, Riccardo, Gornati, Davide, Eleuteri, Simona, Fossaghi, Andrea, Brancaccio, Diego, Manzoni, Leonardo, Ottoboni, Linda, Feo, Luca De, Quattrini, Angelo, Mastrangelo, Eloise, Sorrentino, Luca, Scalone, Emanuele, Comi, Giancarlo, Marinelli, Luciana, Riva, Nilo, Milani, Mario, Seneci, Pierfausto, Martino, Gianvito
Publicado 2020

Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis

por Starost, Laura, Lindner, Maren, Herold, Martin, Xu, Yu Kang T., Drexler, Hannes C. A., Heß, Katharina, Ehrlich, Marc, Ottoboni, Linda, Ruffini, Francesca, Stehling, Martin, Röpke, Albrecht, Thomas, Christian, Schöler, Hans R., Antel, Jack, Winkler, Jürgen, Martino, Gianvito, Klotz, Luisa, Kuhlmann, Tanja
Publicado 2020

Multicolored Stain-free Histopathology with Coherent Raman Imaging

por Freudiger, Christian W., Pfannl, Rolf, Orringer, Daniel A., Saar, Brian G., Ji, Minbiao, Zeng, Qing, Ottoboni, Linda, Ying, Wei, Waeber, Christian, Sims, John. R., De Jager, Philip L., Sagher, Oren, Philbert, Martin A., Xu, Xiaoyin, Kesari, Santosh, Xie, X. Sunney, Young, Geoffrey S.
Publicado 2012

CD33 Alzheimer’s disease locus: Altered monocyte function and amyloid biology

por Bradshaw, Elizabeth M, Chibnik, Lori B, Keenan, Brendan T, Ottoboni, Linda, Raj, Towfique, Tang, Anna, Rosenkrantz, Laura L, Imboywa, Selina, Lee, Michelle, Von Korff, Alina, Morris, Martha C, Evans, Denis A, Johnson, Keith, Sperling, Reisa A, Schneider, Julie A, Bennett, David A, De Jager, Philip L
Publicado 2013

Multiple sclerosis iPS-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivo

por Mozafari, Sabah, Starost, Laura, Manot-Saillet, Blandine, Garcia-Diaz, Beatriz, Xu, Yu Kang T., Roussel, Delphine, Levy, Marion J. F., Ottoboni, Linda, Kim, Kee-Pyo, Schöler, Hans R., Kennedy, Timothy E., Antel, Jack P., Martino, Gianvito, Angulo, Maria Cecilia, Kuhlmann, Tanja, Evercooren, Anne Baron-Van
Publicado 2020

Combined RNA interference and gene replacement therapy targeting MFN2 as proof of principle for the treatment of Charcot–Marie–Tooth type 2A

por Rizzo, Federica, Bono, Silvia, Ruepp, Marc David, Salani, Sabrina, Ottoboni, Linda, Abati, Elena, Melzi, Valentina, Cordiglieri, Chiara, Pagliarani, Serena, De Gioia, Roberta, Anastasia, Alessia, Taiana, Michela, Garbellini, Manuela, Lodato, Simona, Kunderfranco, Paolo, Cazzato, Daniele, Cartelli, Daniele, Lonati, Caterina, Bresolin, Nereo, Comi, Giacomo, Nizzardo, Monica, Corti, Stefania
Publicado 2023

One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2

por Chanoumidou, Konstantina, Hernández-Rodríguez, Benjamín, Windener, Farina, Thomas, Christian, Stehling, Martin, Mozafari, Sabah, Albrecht, Stefanie, Ottoboni, Linda, Antel, Jack, Kim, Kee-Pyo, Velychko, Sergiy, Cui, Qiao Ling, Xu, Yu Kang T., Martino, Gianvito, Winkler, Jürgen, Schöler, Hans R., Baron-Van Evercooren, Anne, Boespflug-Tanguy, Odile, Vaquerizas, Juan M., Ehrlich, Marc, Kuhlmann, Tanja
Publicado 2021

A Whole-Genome Sequencing Study Implicates GRAMD1B in Multiple Sclerosis Susceptibility

por Esposito, Federica, Osiceanu, Ana Maria, Sorosina, Melissa, Ottoboni, Linda, Bollman, Bryan, Santoro, Silvia, Bettegazzi, Barbara, Zauli, Andrea, Clarelli, Ferdinando, Mascia, Elisabetta, Calabria, Andrea, Zacchetti, Daniele, Capra, Ruggero, Ferrari, Maurizio, Provero, Paolo, Lazarevic, Dejan, Cittaro, Davide, Carrera, Paola, Patsopoulos, Nikolaos, Toniolo, Daniela, Sadovnick, A Dessa, Martino, Gianvito, De Jager, Philip L., Comi, Giancarlo, Stupka, Elia, Vilariño-Güell, Carles, Piccio, Laura, Martinelli Boneschi, Filippo
Publicado 2022