The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization

por Oudelaar, A Marieke, Beagrie, Robert A, Kassouf, Mira T, Higgs, Douglas R
Publicado 2021

Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C

por Oudelaar, A. Marieke, Davies, James O.J., Downes, Damien J., Higgs, Douglas R., Hughes, Jim R.
Publicado 2017

Analysis of sub-kilobase chromatin topology reveals nano-scale regulatory interactions with variable dependence on cohesin and CTCF

por Aljahani, Abrar, Hua, Peng, Karpinska, Magdalena A., Quililan, Kimberly, Davies, James O. J., Oudelaar, A. Marieke
Publicado 2022

Between form and function: the complexity of genome folding

por Oudelaar, A. Marieke, Hanssen, Lars L.P., Hardison, Ross C., Kassouf, Mira T., Hughes, Jim R., Higgs, Douglas R.
Publicado 2017

A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus

por Oudelaar, A. Marieke, Harrold, Caroline L., Hanssen, Lars L. P., Telenius, Jelena M., Higgs, Douglas R., Hughes, Jim R.
Publicado 2019

The Mediator complex regulates enhancer-promoter interactions

por Ramasamy, Shyam, Aljahani, Abrar, Karpinska, Magdalena A., Cao, T. B. Ngoc, Velychko, Taras, Cruz, J. Neos, Lidschreiber, Michael, Oudelaar, A. Marieke
Publicado 2023

DeepC: predicting 3D genome folding using megabase-scale transfer learning

por Schwessinger, Ron, Gosden, Matthew, Downes, Damien, Brown, Richard C, Oudelaar, A. Marieke, Telenius, Jelena, Teh, Yee Whye, Lunter, Gerton, Hughes, Jim R.
Publicado 2020

Capture-C: A modular and flexible approach for high-resolution chromosome conformation capture

por Downes, Damien J., Smith, Alastair L., Karpinska, Magdalena A., Velychko, Taras, Rue-Albrecht, Kevin, Sims, David, Milne, Thomas A., Davies, James O.J., Oudelaar, A. Marieke, Hughes, Jim R.
Publicado 2022

Tissue-specific CTCF/Cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo

por Hanssen, Lars L P, Kassouf, Mira T, Oudelaar, A Marieke, Biggs, Daniel, Preece, Chris, Downes, Damien J, Gosden, Matthew, Sharpe, Jacqueline A, Sloane-Stanley, Jacqueline A, Hughes, Jim R, Davies, Benjamin, Higgs, Douglas R
Publicado 2017

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation

por Godfrey, Laura, Crump, Nicholas T., Thorne, Ross, Lau, I-Jun, Repapi, Emmanouela, Dimou, Dimitra, Smith, Alastair L., Harman, Joe R., Telenius, Jelena M., Oudelaar, A. Marieke, Downes, Damien J., Vyas, Paresh, Hughes, Jim R., Milne, Thomas A.
Publicado 2019

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions

por Brown, Jill M., Roberts, Nigel A., Graham, Bryony, Waithe, Dominic, Lagerholm, Christoffer, Telenius, Jelena M., De Ornellas, Sara, Oudelaar, A. Marieke, Scott, Caroline, Szczerbal, Izabela, Babbs, Christian, Kassouf, Mira T., Hughes, Jim R., Higgs, Douglas R., Buckle, Veronica J.
Publicado 2018

Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development

por Owens, Dominic D. G., Anselmi, Giorgio, Oudelaar, A. Marieke, Downes, Damien J., Cavallo, Alessandro, Harman, Joe R., Schwessinger, Ron, Bucakci, Akin, Greder, Lucas, de Ornellas, Sara, Jeziorska, Danuta, Telenius, Jelena, Hughes, Jim R., de Bruijn, Marella F. T. R.
Publicado 2022

Dynamics of the 4D genome during in vivo lineage specification and differentiation

por Oudelaar, A. Marieke, Beagrie, Robert A., Gosden, Matthew, de Ornellas, Sara, Georgiades, Emily, Kerry, Jon, Hidalgo, Daniel, Carrelha, Joana, Shivalingam, Arun, El-Sagheer, Afaf H., Telenius, Jelena M., Brown, Tom, Buckle, Veronica J., Socolovsky, Merav, Higgs, Douglas R., Hughes, Jim R.
Publicado 2020

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains

por Oudelaar, A. Marieke, Davies, James O.J., Hanssen, Lars L.P., Telenius, Jelena M., Schwessinger, Ron, Liu, Yu, Brown, Jill M., Downes, Damien J., Chiariello, Andrea M., Bianco, Simona, Nicodemi, Mario, Buckle, Veronica J., Dekker, Job, Higgs, Douglas R., Hughes, Jim R.
Publicado 2018

High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale

por Downes, Damien J., Beagrie, Robert A., Gosden, Matthew E., Telenius, Jelena, Carpenter, Stephanie J., Nussbaum, Lea, De Ornellas, Sara, Sergeant, Martin, Eijsbouts, Chris Q., Schwessinger, Ron, Kerry, Jon, Roberts, Nigel, Shivalingam, Arun, El-Sagheer, Afaf, Oudelaar, A. Marieke, Brown, Tom, Buckle, Veronica J., Davies, James O. J., Hughes, Jim R.
Publicado 2021