Inhibition of miR-146a Expression and Regulation of Endotoxin Tolerance by Rhesus Theta-Defensin-1

por Tongaonkar, Prasad, Trinh, Katie K., Ouellette, André J., Selsted, Michael E.
Publicado 2023

Differential Susceptibility of Bacteria to Mouse Paneth Cell α-Defensins under Anaerobic Conditions

por Mastroianni, Jennifer R., Lu, Wuyuan, Selsted, Michael E., Ouellette, André J.
Publicado 2014

Host Defense Peptides as Templates for Antifungal Drug Development

por Basso, Virginia, Tran, Dat Q., Ouellette, André J., Selsted, Michael E.
Publicado 2020

High Fidelity Processing and Activation of the Human α-Defensin HNP1 Precursor by Neutrophil Elastase and Proteinase 3

por Tongaonkar, Prasad, Golji, Amir E., Tran, Patti, Ouellette, André J., Selsted, Michael E.
Publicado 2012

Rhesus macaque θ‐defensin RTD‐1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF‐κB and MAPK pathways

por Tongaonkar, Prasad, Trinh, Katie K., Schaal, Justin B., Tran, Dat, Gulko, Percio S., Ouellette, André J., Selsted, Michael E.
Publicado 2015

Anti-Inflammatory Effects of RTD-1 in a Murine Model of Chronic Pseudomonas aeruginosa Lung Infection: Inhibition of NF-κB, Inflammasome Gene Expression, and Pro-IL-1β Biosynthesis...

por Dughbaj, Mansour A., Jayne, Jordanna G., Park, A Young J., Bensman, Timothy J., Algorri, Marquerita, Ouellette, Andre J., Selsted, Michael E., Beringer, Paul M.
Publicado 2021

A novel role for lipid droplets in the organismal antibacterial response

por Anand, Preetha, Cermelli, Silvia, Li, Zhihuan, Kassan, Adam, Bosch, Marta, Sigua, Robilyn, Huang, Lan, Ouellette, Andre J, Pol, Albert, Welte, Michael A, Gross, Steven P
Publicado 2012

Rhesus Macaque Theta Defensins Suppress Inflammatory Cytokines and Enhance Survival in Mouse Models of Bacteremic Sepsis

por Schaal, Justin B., Tran, Dat, Tran, Patti, Ösapay, George, Trinh, Katie, Roberts, Kevin D., Brasky, Kathleen M., Tongaonkar, Prasad, Ouellette, André J., Selsted, Michael E.
Publicado 2012

Killing of Staphylococci by θ-Defensins Involves Membrane Impairment and Activation of Autolytic Enzymes

por Wilmes, Miriam, Stockem, Marina, Bierbaum, Gabriele, Schlag, Martin, Götz, Friedrich, Tran, Dat Q., Schaal, Justin B., Ouellette, André J., Selsted, Michael E., Sahl, Hans-Georg
Publicado 2014

A host-directed macrocyclic peptide therapeutic for MDR gram negative bacterial infections

por Schaal, Justin B., Eriguchi, Yoshihiro, Tran, Dat Q., Tran, Patti A., Hawes, Chase, Cabebe, Anthony E., Pike, Kaitlyn, Trinh, Katie, Ouellette, André J., Selsted, Michael E.
Publicado 2021

Decreased Paneth cell α-defensins promote fibrosis in a choline-deficient L-amino acid-defined high-fat diet-induced mouse model of nonalcoholic steatohepatitis via disrupting inte...

por Nakamura, Shunta, Nakamura, Kiminori, Yokoi, Yuki, Shimizu, Yu, Ohira, Shuya, Hagiwara, Mizu, Song, Zihao, Gan, Li, Aizawa, Tomoyasu, Hashimoto, Daigo, Teshima, Takanori, Ouellette, Andre J., Ayabe, Tokiyoshi
Publicado 2023

Rhesus Theta Defensin 1 Promotes Long Term Survival in Systemic Candidiasis by Host Directed Mechanisms

por Basso, Virginia, Tran, Dat Q., Schaal, Justin B., Tran, Patti, Eriguchi, Yoshihiro, Ngole, Diana, Cabebe, Anthony E., Park, A. young, Beringer, Paul M., Ouellette, André J., Selsted, Michael E.
Publicado 2019

Defensins Potentiate a Neutralizing Antibody Response to Enteric Viral Infection

por Gounder, Anshu P., Myers, Nicolle D., Treuting, Piper M., Bromme, Beth A., Wilson, Sarah S., Wiens, Mayim E., Lu, Wuyuan, Ouellette, André J., Spindler, Katherine R., Parks, William C., Smith, Jason G.
Publicado 2016

Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide

por Schaal, Justin B., Tran, Dat Q., Subramanian, Akshay, Patel, Reshma, Laragione, Teresina, Roberts, Kevin D., Trinh, Katie, Tongaonkar, Prasad, Tran, Patti A., Minond, Dmitriy, Fields, Gregg B., Beringer, Paul, Ouellette, André J., Gulko, Percio S., Selsted, Michael E.
Publicado 2017

PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice

por Canale, Vinicius, Spalinger, Marianne R., Alvarez, Rocio, Sayoc-Becerra, Anica, Sanati, Golshid, Manz, Salomon, Chatterjee, Pritha, Santos, Alina N., Lei, Hillmin, Jahng, Sharon, Chu, Timothy, Shawki, Ali, Hanson, Elaine, Eckmann, Lars, Ouellette, André J., McCole, Declan F.
Publicado 2023

p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair

por Lai, Keane K. Y., Hu, Xiaohui, Chosa, Keisuke, Nguyen, Cu, Lin, David P., Lai, Keith K., Kato, Nobuo, Higuchi, Yusuke, Highlander, Sarah K., Melendez, Elizabeth, Eriguchi, Yoshihiro, Fueger, Patrick T., Ouellette, Andre J., Chimge, Nyam-Osor, Ono, Masaya, Kahn, Michael
Publicado 2021