Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases

por Perez-Pinera, Pablo, Ousterout, David G., Brown, Matthew T., Gersbach, Charles A.
Publicado 2012

Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector

por Kabadi, Ami M., Ousterout, David G., Hilton, Isaac B., Gersbach, Charles A.
Publicado 2014

Multiplex CRISPR/Cas9-Based Genome Editing for Correction of Dystrophin Mutations that Cause Duchenne Muscular Dystrophy

por Ousterout, David G., Kabadi, Ami M., Thakore, Pratiksha I., Majoros, William H., Reddy, Timothy E., Gersbach, Charles A.
Publicado 2015

Correction of Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients Through Genomic Excision of Exon 51 by Zinc Finger Nucleases

por Ousterout, David G, Kabadi, Ami M, Thakore, Pratiksha I, Perez-Pinera, Pablo, Brown, Matthew T, Majoros, William H, Reddy, Timothy E, Gersbach, Charles A
Publicado 2015

Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain

por Kabadi, Ami M., Thakore, Pratiksha I., Vockley, Christopher M., Ousterout, David G., Gibson, Tyler M., Guilak, Farshid, Reddy, Timothy E., Gersbach, Charles A.
Publicado 2014

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

por Perez-Pinera, Pablo, Ousterout, David G., Brunger, Jonathan M., Farin, Alicia M., Glass, Katherine A., Guilak, Farshid, Crawford, Gregory E., Hartemink, Alexander J., Gersbach, Charles A.
Publicado 2013

Reading Frame Correction by Targeted Genome Editing Restores Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients

por Ousterout, David G, Perez-Pinera, Pablo, Thakore, Pratiksha I, Kabadi, Ami M, Brown, Matthew T, Qin, Xiaoxia, Fedrigo, Olivier, Mouly, Vincent, Tremblay, Jacques P, Gersbach, Charles A
Publicado 2013

In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials

por Selle, Kurt, Fletcher, Joshua R., Tuson, Hannah, Schmitt, Daniel S., McMillan, Lana, Vridhambal, Gowrinarayani S., Rivera, Alissa J., Montgomery, Stephanie A., Fortier, Louis-Charles, Barrangou, Rodolphe, Theriot, Casey M., Ousterout, David G.
Publicado 2020

Highly active zinc-finger nucleases by extended modular assembly

por Bhakta, Mital S., Henry, Isabelle M., Ousterout, David G., Das, Kumitaa Theva, Lockwood, Sarah H., Meckler, Joshua F., Wallen, Mark C., Zykovich, Artem, Yu, Yawei, Leo, Heather, Xu, Lifeng, Gersbach, Charles A., Segal, David J.
Publicado 2013

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

por Perez-Pinera, Pablo, Kocak, D. Dewran, Vockley, Christopher M., Adler, Andrew F., Kabadi, Ami M., Polstein, Lauren R., Thakore, Pratiksha I., Glass, Katherine A., Ousterout, David G., Leong, Kam W., Guilak, Farshid, Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Publicado 2013