Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the grow...

por Taieb, Mahdia, Ghannoum, Dima, Barré, Lydia, Ouzzine, Mohamed
Publicado 2023

TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early...

por Khan, Sajida, Sbeity, Malak, Foulquier, François, Barré, Lydia, Ouzzine, Mohamed
Publicado 2021

The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication

por Ouzzine, Mohamed, Gulberti, Sandrine, Ramalanjaona, Nick, Magdalou, Jacques, Fournel-Gigleux, Sylvie
Publicado 2014

Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma

por Qin, Jun, Shaukat, Irfan, Mainard, Didier, Netter, Patrick, Barré, Lydia, Ouzzine, Mohamed
Publicado 2019

Targeting of Proteoglycan Synthesis Pathway: A New Strategy to Counteract Excessive Matrix Proteoglycan Deposition and Transforming Growth Factor-β1-Induced Fibrotic Phenotype in L...

por Shaukat, Irfan, Barré, Lydia, Venkatesan, Narayanan, Li, Dong, Jaquinet, Jean-Claude, Fournel-Gigleux, Sylvie, Ouzzine, Mohamed
Publicado 2016

Differential Effects of D-Galactose Supplementation on Golgi Glycosylation Defects in TMEM165 Deficiency

por Durin, Zoé, Houdou, Marine, Morelle, Willy, Barré, Lydia, Layotte, Aurore, Legrand, Dominique, Ouzzine, Mohamed, Foulquier, François
Publicado 2022

Xylosyltransferase-I Regulates Glycosaminoglycan Synthesis during the Pathogenic Process of Human Osteoarthritis

por Venkatesan, Narayanan, Barré, Lydia, Bourhim, Mustapha, Magdalou, Jacques, Mainard, Didier, Netter, Patrick, Fournel-Gigleux, Sylvie, Ouzzine, Mohamed
Publicado 2012

Modifications of the Glycosaminoglycan-Linkage Region of Proteoglycans: Phosphorylation and Sulfation Determine the Activity of the Human ß1,4-Galactosyltransferase 7 and ß1,3-Gluc...

por Gulberti, Sandrine, Lattard, Virginie, Fondeur, Magali, Jacquinet, Jean-Claude, Mulliert, Guillermo, Netter, Patrick, Magdalou, Jacques, Ouzzine, Mohamed, Fournel-Gigleux, Sylvie
Publicado 2005

Probing the Acceptor Active Site Organization of the Human Recombinant β1,4-Galactosyltransferase 7 and Design of Xyloside-based Inhibitors

por Saliba, Mineem, Ramalanjaona, Nick, Gulberti, Sandrine, Bertin-Jung, Isabelle, Thomas, Aline, Dahbi, Samir, Lopin-Bon, Chrystel, Jacquinet, Jean-Claude, Breton, Christelle, Ouzzine, Mohamed, Fournel-Gigleux, Sylvie
Publicado 2015